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Items: 1 to 20 of 124

1.

Into the Fourth Dimension: Dysregulation of Genome Architecture in Aging and Alzheimer's Disease.

Winick-Ng W, Rylett RJ.

Front Mol Neurosci. 2018 Feb 28;11:60. doi: 10.3389/fnmol.2018.00060. eCollection 2018. Review.

2.

Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models.

Lee CYD, Daggett A, Gu X, Jiang LL, Langfelder P, Li X, Wang N, Zhao Y, Park CS, Cooper Y, Ferando I, Mody I, Coppola G, Xu H, Yang XW.

Neuron. 2018 Mar 7;97(5):1032-1048.e5. doi: 10.1016/j.neuron.2018.02.002.

PMID:
29518357
3.

Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer's disease.

Zhang Q, Ma C, Gearing M, Wang PG, Chin LS, Li L.

Acta Neuropathol Commun. 2018 Mar 1;6(1):19. doi: 10.1186/s40478-018-0524-2.

4.

Systems healthcare: a holistic paradigm for tomorrow.

Fiandaca MS, Mapstone M, Connors E, Jacobson M, Monuki ES, Malik S, Macciardi F, Federoff HJ.

BMC Syst Biol. 2017 Dec 19;11(1):142. doi: 10.1186/s12918-017-0521-2. Review.

5.

A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain.

Umoh ME, Dammer EB, Dai J, Duong DM, Lah JJ, Levey AI, Gearing M, Glass JD, Seyfried NT.

EMBO Mol Med. 2018 Jan;10(1):48-62. doi: 10.15252/emmm.201708202.

6.

Neuropathological and transcriptomic characteristics of the aged brain.

Miller JA, Guillozet-Bongaarts A, Gibbons LE, Postupna N, Renz A, Beller AE, Sunkin SM, Ng L, Rose SE, Smith KA, Szafer A, Barber C, Bertagnolli D, Bickley K, Brouner K, Caldejon S, Chapin M, Chua ML, Coleman NM, Cudaback E, Cuhaciyan C, Dalley RA, Dee N, Desta T, Dolbeare TA, Dotson NI, Fisher M, Gaudreault N, Gee G, Gilbert TL, Goldy J, Griffin F, Habel C, Haradon Z, Hejazinia N, Hellstern LL, Horvath S, Howard K, Howard R, Johal J, Jorstad NL, Josephsen SR, Kuan CL, Lai F, Lee E, Lee F, Lemon T, Li X, Marshall DA, Melchor J, Mukherjee S, Nyhus J, Pendergraft J, Potekhina L, Rha EY, Rice S, Rosen D, Sapru A, Schantz A, Shen E, Sherfield E, Shi S, Sodt AJ, Thatra N, Tieu M, Wilson AM, Montine TJ, Larson EB, Bernard A, Crane PK, Ellenbogen RG, Keene CD, Lein E.

Elife. 2017 Nov 9;6. pii: e31126. doi: 10.7554/eLife.31126.

7.

Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease.

McKenzie AT, Moyon S, Wang M, Katsyv I, Song WM, Zhou X, Dammer EB, Duong DM, Aaker J, Zhao Y, Beckmann N, Wang P, Zhu J, Lah JJ, Seyfried NT, Levey AI, Katsel P, Haroutunian V, Schadt EE, Popko B, Casaccia P, Zhang B.

Mol Neurodegener. 2017 Nov 6;12(1):82. doi: 10.1186/s13024-017-0219-3.

8.

Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases.

Allen M, Wang X, Burgess JD, Watzlawik J, Serie DJ, Younkin CS, Nguyen T, Malphrus KG, Lincoln S, Carrasquillo MM, Ho C, Chakrabarty P, Strickland S, Murray ME, Swarup V, Geschwind DH, Seyfried NT, Dammer EB, Lah JJ, Levey AI, Golde TE, Funk C, Li H, Price ND, Petersen RC, Graff-Radford NR, Younkin SG, Dickson DW, Crook JR, Asmann YW, Ertekin-Taner N.

Alzheimers Dement. 2018 Mar;14(3):352-366. doi: 10.1016/j.jalz.2017.09.012. Epub 2017 Oct 31.

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Integrative model of leukocyte genomics and organ dysfunction in heart failure patients requiring mechanical circulatory support: a prospective observational study.

Wisniewski N, Bondar G, Rau C, Chittoor J, Chang E, Esmaeili A, Cadeiras M, Deng M.

BMC Med Genomics. 2017 Aug 29;10(1):52. doi: 10.1186/s12920-017-0288-8.

12.

Protein homeostasis of a metastable subproteome associated with Alzheimer's disease.

Kundra R, Ciryam P, Morimoto RI, Dobson CM, Vendruscolo M.

Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):E5703-E5711. doi: 10.1073/pnas.1618417114. Epub 2017 Jun 26.

13.

Dissecting the Molecular Mechanisms of Neurodegenerative Diseases through Network Biology.

Santiago JA, Bottero V, Potashkin JA.

Front Aging Neurosci. 2017 May 29;9:166. doi: 10.3389/fnagi.2017.00166. eCollection 2017.

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A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease.

Seyfried NT, Dammer EB, Swarup V, Nandakumar D, Duong DM, Yin L, Deng Q, Nguyen T, Hales CM, Wingo T, Glass J, Gearing M, Thambisetty M, Troncoso JC, Geschwind DH, Lah JJ, Levey AI.

Cell Syst. 2017 Jan 25;4(1):60-72.e4. doi: 10.1016/j.cels.2016.11.006. Epub 2016 Dec 15.

17.

Transcriptome sequencing of the choroid plexus in schizophrenia.

Kim S, Hwang Y, Lee D, Webster MJ.

Transl Psychiatry. 2016 Nov 29;6(11):e964. doi: 10.1038/tp.2016.229.

18.

Drug Repositioning through Systematic Mining of Gene Coexpression Networks in Cancer.

Ivliev AE, 't Hoen PA, Borisevich D, Nikolsky Y, Sergeeva MG.

PLoS One. 2016 Nov 8;11(11):e0165059. doi: 10.1371/journal.pone.0165059. eCollection 2016.

20.

Widespread white matter and conduction defects in PSEN1-related spastic paraparesis.

Soosman SK, Joseph-Mathurin N, Braskie MN, Bordelon YM, Wharton D, Casado M, Coppola G, McCallum H, Nuwer M, Coutin-Churchman P, Apostolova LG, Benzinger T, Ringman JM.

Neurobiol Aging. 2016 Nov;47:201-209. doi: 10.1016/j.neurobiolaging.2016.07.030. Epub 2016 Aug 8.

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