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Items: 15

1.

Inositol Polyphosphate-4-Phosphatase Type I Negatively Regulates Phagocytosis via Dephosphorylation of Phagosomal PtdIns(3,4)P2.

Nigorikawa K, Hazeki K, Sasaki J, Omori Y, Miyake M, Morioka S, Guo Y, Sasaki T, Hazeki O.

PLoS One. 2015 Nov 4;10(11):e0142091. doi: 10.1371/journal.pone.0142091.

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Lithium ameliorates lipopolysaccharide-induced microglial activation via inhibition of toll-like receptor 4 expression by activating the PI3K/Akt/FoxO1 pathway.

Dong H, Zhang X, Dai X, Lu S, Gui B, Jin W, Zhang S, Zhang S, Qian Y.

J Neuroinflammation. 2014 Aug 14;11:140. doi: 10.1186/s12974-014-0140-4.

4.

Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling.

McGuire VA, Gray A, Monk CE, Santos SG, Lee K, Aubareda A, Crowe J, Ronkina N, Schwermann J, Batty IH, Leslie NR, Dean JL, O'Keefe SJ, Boothby M, Gaestel M, Arthur JS.

Mol Cell Biol. 2013 Nov;33(21):4152-65. doi: 10.1128/MCB.01691-12.

5.

A critical role for MAPK signalling pathways in the transcriptional regulation of toll like receptors.

Peroval MY, Boyd AC, Young JR, Smith AL.

PLoS One. 2013;8(2):e51243. doi: 10.1371/journal.pone.0051243.

6.

The role of phosphoinositide 3-kinase signaling in intestinal inflammation.

Cahill CM, Rogers JT, Walker WA.

J Signal Transduct. 2012;2012:358476. doi: 10.1155/2012/358476.

7.

TLR4-mediated AKT activation is MyD88/TRIF dependent and critical for induction of oxidative phosphorylation and mitochondrial transcription factor A in murine macrophages.

Bauerfeld CP, Rastogi R, Pirockinaite G, Lee I, Hüttemann M, Monks B, Birnbaum MJ, Franchi L, Nuñez G, Samavati L.

J Immunol. 2012 Mar 15;188(6):2847-57. doi: 10.4049/jimmunol.1102157.

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9.

FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages.

Fan W, Morinaga H, Kim JJ, Bae E, Spann NJ, Heinz S, Glass CK, Olefsky JM.

EMBO J. 2010 Dec 15;29(24):4223-36. doi: 10.1038/emboj.2010.268.

10.

The p110α and p110β isoforms of class I phosphatidylinositol 3-kinase are involved in toll-like receptor 5 signaling in epithelial cells.

Ivison SM, Khan MA, Graham NR, Shobab LA, Yao Y, Kifayet A, Sly LM, Steiner TS.

Mediators Inflamm. 2010;2010. pii: 652098. doi: 10.1155/2010/652098.

11.

High-throughput screening for TLR3-IFN regulatory factor 3 signaling pathway modulators identifies several antipsychotic drugs as TLR inhibitors.

Zhu J, Smith K, Hsieh PN, Mburu YK, Chattopadhyay S, Sen GC, Sarkar SN.

J Immunol. 2010 May 15;184(10):5768-76. doi: 10.4049/jimmunol.0903559.

12.

Toll-like receptor signaling in cell proliferation and survival.

Li X, Jiang S, Tapping RI.

Cytokine. 2010 Jan;49(1):1-9. doi: 10.1016/j.cyto.2009.08.010. Review.

13.

FoxO1 links insulin resistance to proinflammatory cytokine IL-1beta production in macrophages.

Su D, Coudriet GM, Hyun Kim D, Lu Y, Perdomo G, Qu S, Slusher S, Tse HM, Piganelli J, Giannoukakis N, Zhang J, Dong HH.

Diabetes. 2009 Nov;58(11):2624-33. doi: 10.2337/db09-0232.

14.

Should individual PI3 kinase isoforms be targeted in cancer?

Jia S, Roberts TM, Zhao JJ.

Curr Opin Cell Biol. 2009 Apr;21(2):199-208. doi: 10.1016/j.ceb.2008.12.007. Review.

15.

SHIP prevents lipopolysaccharide from triggering an antiviral response in mice.

Sly LM, Hamilton MJ, Kuroda E, Ho VW, Antignano FL, Omeis SL, van Netten-Thomas CJ, Wong D, Brugger HK, Williams O, Feldman ME, Houseman BT, Fiedler D, Shokat KM, Krystal G.

Blood. 2009 Mar 26;113(13):2945-54. doi: 10.1182/blood-2008-06-166082.

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