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Items: 1 to 20 of 23


Current Perspective in the Discovery of Anti-aging Agents from Natural Products.

Ding AJ, Zheng SQ, Huang XB, Xing TK, Wu GS, Sun HY, Qi SH, Luo HR.

Nat Prod Bioprospect. 2017 Oct;7(5):335-404. doi: 10.1007/s13659-017-0135-9. Epub 2017 May 31. Review.


Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects.

Lucanic M, Plummer WT, Chen E, Harke J, Foulger AC, Onken B, Coleman-Hulbert AL, Dumas KJ, Guo S, Johnson E, Bhaumik D, Xue J, Crist AB, Presley MP, Harinath G, Sedore CA, Chamoli M, Kamat S, Chen MK, Angeli S, Chang C, Willis JH, Edgar D, Royal MA, Chao EA, Patel S, Garrett T, Ibanez-Ventoso C, Hope J, Kish JL, Guo M, Lithgow GJ, Driscoll M, Phillips PC.

Nat Commun. 2017 Feb 21;8:14256. doi: 10.1038/ncomms14256.


Angiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life Span.

Kumar S, Dietrich N, Kornfeld K.

PLoS Genet. 2016 Feb 26;12(2):e1005866. doi: 10.1371/journal.pgen.1005866. eCollection 2016 Feb.


Green Tea Extract Induces the Resistance of Caenorhabditis elegans against Oxidative Stress.

Abbas S, Wink M.

Antioxidants (Basel). 2014 Mar 4;3(1):129-43. doi: 10.3390/antiox3010129.


Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality.

Rangaraju S, Solis GM, Thompson RC, Gomez-Amaro RL, Kurian L, Encalada SE, Niculescu AB 3rd, Salomon DR, Petrascheck M.

Elife. 2015 Dec 1;4:e08833. doi: 10.7554/eLife.08833. Erratum in: Elife. 2016 Dec 30;5:.


Healthspan Pharmacology.

Jafari M.

Rejuvenation Res. 2015 Dec;18(6):573-80. doi: 10.1089/rej.2015.1774. Epub 2015 Nov 10.


Cells adapt to the epigenomic disruption caused by histone deacetylase inhibitors through a coordinated, chromatin-mediated transcriptional response.

Halsall JA, Turan N, Wiersma M, Turner BM.

Epigenetics Chromatin. 2015 Sep 16;8:29. doi: 10.1186/s13072-015-0021-9. eCollection 2015.


10-Hydroxy-2-decenoic Acid, the Major Lipid Component of Royal Jelly, Extends the Lifespan of Caenorhabditis elegans through Dietary Restriction and Target of Rapamycin Signaling.

Honda Y, Araki Y, Hata T, Ichihara K, Ito M, Tanaka M, Honda S.

J Aging Res. 2015;2015:425261. doi: 10.1155/2015/425261. Epub 2015 Feb 19.


D-ß-hydroxybutyrate: an anti-aging ketone body.

Edwards C, Copes N, Bradshaw PC.

Oncotarget. 2015 Feb 28;6(6):3477-8. No abstract available.


Mechanisms underlying the anti-aging and anti-tumor effects of lithocholic bile acid.

Arlia-Ciommo A, Piano A, Svistkova V, Mohtashami S, Titorenko VI.

Int J Mol Sci. 2014 Sep 18;15(9):16522-43. doi: 10.3390/ijms150916522. Review.


D-beta-hydroxybutyrate extends lifespan in C. elegans.

Edwards C, Canfield J, Copes N, Rehan M, Lipps D, Bradshaw PC.

Aging (Albany NY). 2014 Aug;6(8):621-44.


Mated progeny production is a biomarker of aging in Caenorhabditis elegans.

Pickett CL, Dietrich N, Chen J, Xiong C, Kornfeld K.

G3 (Bethesda). 2013 Dec 9;3(12):2219-32. doi: 10.1534/g3.113.008664.


Ketone bodies as signaling metabolites.

Newman JC, Verdin E.

Trends Endocrinol Metab. 2014 Jan;25(1):42-52. doi: 10.1016/j.tem.2013.09.002. Epub 2013 Oct 18. Review.


Drug absorption efficiency in Caenorhbditis elegans delivered by different methods.

Zheng SQ, Ding AJ, Li GP, Wu GS, Luo HR.

PLoS One. 2013;8(2):e56877. doi: 10.1371/journal.pone.0056877. Epub 2013 Feb 25.


Pharmacological lifespan extension of invertebrates.

Lucanic M, Lithgow GJ, Alavez S.

Ageing Res Rev. 2013 Jan;12(1):445-58. doi: 10.1016/j.arr.2012.06.006. Epub 2012 Jul 6. Review.


Neuron-specific proteotoxicity of mutant ataxin-3 in C. elegans: rescue by the DAF-16 and HSF-1 pathways.

Teixeira-Castro A, Ailion M, Jalles A, Brignull HR, Vilaça JL, Dias N, Rodrigues P, Oliveira JF, Neves-Carvalho A, Morimoto RI, Maciel P.

Hum Mol Genet. 2011 Aug 1;20(15):2996-3009. doi: 10.1093/hmg/ddr203. Epub 2011 May 5.


Measuring Caenorhabditis elegans life span in 96 well microtiter plates.

Solis GM, Petrascheck M.

J Vis Exp. 2011 Mar 18;(49). pii: 2496. doi: 10.3791/2496.


Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity.

Ching TT, Chiang WC, Chen CS, Hsu AL.

Aging Cell. 2011 Jun;10(3):506-19. doi: 10.1111/j.1474-9726.2011.00688.x. Epub 2011 Apr 7.


Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor.

Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J.

PLoS One. 2010 Feb 17;5(2):e9267. doi: 10.1371/journal.pone.0009267.

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