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Items: 1 to 20 of 38

1.

Spatially- and temporally-controlled postnatal p53 knockdown cooperates with embryonic Schwann cell precursor Nf1 gene loss to promote malignant peripheral nerve sheath tumor formation.

Hirbe AC, Dahiya S, Friedmann-Morvinski D, Verma IM, Clapp DW, Gutmann DH.

Oncotarget. 2016 Feb 16;7(7):7403-14. doi: 10.18632/oncotarget.7232.

2.

Runx1 contributes to neurofibromatosis type 1 neurofibroma formation.

Li H, Zhao X, Yan X, Jessen WJ, Kim MO, Dombi E, Liu PP, Huang G, Wu J.

Oncogene. 2016 Mar 17;35(11):1468-74. doi: 10.1038/onc.2015.207.

3.

Regulation of Peripheral Nerve Myelin Maintenance by Gene Repression through Polycomb Repressive Complex 2.

Ma KH, Hung HA, Srinivasan R, Xie H, Orkin SH, Svaren J.

J Neurosci. 2015 Jun 3;35(22):8640-52. doi: 10.1523/JNEUROSCI.2257-14.2015.

4.

Whole Exome Sequencing Reveals the Order of Genetic Changes during Malignant Transformation and Metastasis in a Single Patient with NF1-plexiform Neurofibroma.

Hirbe AC, Dahiya S, Miller CA, Li T, Fulton RS, Zhang X, McDonald S, DeSchryver K, Duncavage EJ, Walrath J, Reilly KM, Abel HJ, Pekmezci M, Perry A, Ley TJ, Gutmann DH.

Clin Cancer Res. 2015 Sep 15;21(18):4201-11. doi: 10.1158/1078-0432.CCR-14-3049.

5.

A RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressor.

Ratner N, Miller SJ.

Nat Rev Cancer. 2015 May;15(5):290-301. doi: 10.1038/nrc3911. Review.

6.

Neural Crest-Specific TSC1 Deletion in Mice Leads to Sclerotic Craniofacial Bone Lesion.

Fang F, Sun S, Wang L, Guan JL, Giovannini M, Zhu Y, Liu F.

J Bone Miner Res. 2015 Jul;30(7):1195-205. doi: 10.1002/jbmr.2447.

7.

Cells of origin in the embryonic nerve roots for NF1-associated plexiform neurofibroma.

Chen Z, Liu C, Patel AJ, Liao CP, Wang Y, Le LQ.

Cancer Cell. 2014 Nov 10;26(5):695-706. doi: 10.1016/j.ccell.2014.09.009.

8.

Arsenic trioxide induces differentiation of CD133+ hepatocellular carcinoma cells and prolongs posthepatectomy survival by targeting GLI1 expression in a mouse model.

Zhang KZ, Zhang QB, Zhang QB, Sun HC, Ao JY, Chai ZT, Zhu XD, Lu L, Zhang YY, Bu Y, Kong LQ, Tang ZY.

J Hematol Oncol. 2014 Mar 30;7:28. doi: 10.1186/1756-8722-7-28.

9.

Retroperitoneal malignant peripheral nerve sheath tumor replacing an absent kidney in a child.

Alavi S, Arzanian MT, Nilipour Y.

Case Rep Oncol Med. 2013;2013:627472. doi: 10.1155/2013/627472.

10.

EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis.

Zhang P, Garnett J, Creighton CJ, Al Sannaa GA, Igram DR, Lazar A, Liu X, Liu C, Pollock RE.

J Pathol. 2014 Feb;232(3):308-18. doi: 10.1002/path.4294. Erratum in: J Pathol. 2014 Jul;233(3):320. Igram, Davis R [corrected to Ingram, Davis R].

11.

The characterisation of Pax3 expressant cells in adult peripheral nerve.

Blake JA, Ziman MR.

PLoS One. 2013;8(3):e59184. doi: 10.1371/journal.pone.0059184.

12.

CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors.

Mo W, Chen J, Patel A, Zhang L, Chau V, Li Y, Cho W, Lim K, Xu J, Lazar AJ, Creighton CJ, Bolshakov S, McKay RM, Lev D, Le LQ, Parada LF.

Cell. 2013 Feb 28;152(5):1077-90. doi: 10.1016/j.cell.2013.01.053.

13.

Malignant peripheral nerve sheath tumor invasion requires aberrantly expressed EGF receptors and is variably enhanced by multiple EGF family ligands.

Byer SJ, Brossier NM, Peavler LT, Eckert JM, Watkins S, Roth KA, Carroll SL.

J Neuropathol Exp Neurol. 2013 Mar;72(3):219-33. doi: 10.1097/NEN.0b013e3182859939.

14.

MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors.

Jessen WJ, Miller SJ, Jousma E, Wu J, Rizvi TA, Brundage ME, Eaves D, Widemann B, Kim MO, Dombi E, Sabo J, Hardiman Dudley A, Niwa-Kawakita M, Page GP, Giovannini M, Aronow BJ, Cripe TP, Ratner N.

J Clin Invest. 2013 Jan;123(1):340-7. doi: 10.1172/JCI60578.

15.

Skin-derived precursors as a source of progenitors for cutaneous nerve regeneration.

Chen Z, Pradhan S, Liu C, Le LQ.

Stem Cells. 2012 Oct;30(10):2261-70. doi: 10.1002/stem.1186.

16.

Ras-driven transcriptome analysis identifies aurora kinase A as a potential malignant peripheral nerve sheath tumor therapeutic target.

Patel AV, Eaves D, Jessen WJ, Rizvi TA, Ecsedy JA, Qian MG, Aronow BJ, Perentesis JP, Serra E, Cripe TP, Miller SJ, Ratner N.

Clin Cancer Res. 2012 Sep 15;18(18):5020-30. doi: 10.1158/1078-0432.CCR-12-1072.

17.

Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development.

Shin J, Padmanabhan A, de Groh ED, Lee JS, Haidar S, Dahlberg S, Guo F, He S, Wolman MA, Granato M, Lawson ND, Wolfe SA, Kim SH, Solnica-Krezel L, Kanki JP, Ligon KL, Epstein JA, Look AT.

Dis Model Mech. 2012 Nov;5(6):881-94. doi: 10.1242/dmm.009779.

18.

Skin-derived precursor cells as an in vitro modelling tool for the study of type 1 neurofibromatosis.

GutiƩrrez-Rivera A, Iribar H, Tuneu A, Izeta A.

Stem Cells Int. 2012;2012:646725. doi: 10.1155/2012/646725.

19.

Tumorigenic cells are common in mouse MPNSTs but their frequency depends upon tumor genotype and assay conditions.

Buchstaller J, McKeever PE, Morrison SJ.

Cancer Cell. 2012 Feb 14;21(2):240-52. doi: 10.1016/j.ccr.2011.12.027.

20.

Pathology of peripheral nerve sheath tumors: diagnostic overview and update on selected diagnostic problems.

Rodriguez FJ, Folpe AL, Giannini C, Perry A.

Acta Neuropathol. 2012 Mar;123(3):295-319. doi: 10.1007/s00401-012-0954-z. Review.

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