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Items: 1 to 20 of 62

1.

p53 Mediates Failure of Human Definitive Hematopoiesis in Dyskeratosis Congenita.

Fok WC, Niero ELO, Dege C, Brenner KA, Sturgeon CM, Batista LFZ.

Stem Cell Reports. 2017 Aug 8;9(2):409-418. doi: 10.1016/j.stemcr.2017.06.015. Epub 2017 Jul 27.

2.

Telomere Length Recovery: A Strong Predictor of Overall Survival in Acute Promyelocytic Leukemia.

Baljevic M, Dumitriu B, Lee JW, Paietta EM, Wiernik PH, Racevskis J, Chen C, Stein EM, Gallagher RE, Rowe JM, Appelbaum FR, Powell BL, Larson RA, Coutré SE, Lancet J, Litzow MR, Luger SM, Young NS, Tallman MS.

Acta Haematol. 2016;136(4):210-218. Epub 2016 Sep 16.

3.

Telomerase Activation in Hematological Malignancies.

Ropio J, Merlio JP, Soares P, Chevret E.

Genes (Basel). 2016 Sep 7;7(9). pii: E61. doi: 10.3390/genes7090061. Review.

4.

Structural conservation in the template/pseudoknot domain of vertebrate telomerase RNA from teleost fish to human.

Wang Y, Yesselman JD, Zhang Q, Kang M, Feigon J.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):E5125-34. doi: 10.1073/pnas.1607411113. Epub 2016 Aug 16.

5.

Therapeutic Targeting of Telomerase.

Jäger K, Walter M.

Genes (Basel). 2016 Jul 21;7(7). pii: E39. doi: 10.3390/genes7070039. Review.

6.

Hereditary melanoma: Update on syndromes and management: Emerging melanoma cancer complexes and genetic counseling.

Soura E, Eliades PJ, Shannon K, Stratigos AJ, Tsao H.

J Am Acad Dermatol. 2016 Mar;74(3):411-20; quiz 421-2. doi: 10.1016/j.jaad.2015.08.037. Review.

7.

A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition.

Stockklausner C, Raffel S, Klermund J, Bandapalli OR, Beier F, Brümmendorf TH, Bürger F, Sauer SW, Hoffmann GF, Lorenz H, Tagliaferri L, Nowak D, Hofmann WK, Buergermeister R, Kerber C, Rausch T, Korbel JO, Luke B, Trumpp A, Kulozik AE.

Aging (Albany NY). 2015 Nov;7(11):911-27.

8.

Downregulation of Protection of Telomeres 1 expression in myelodysplastic syndromes with 7q deletion.

Cabrero M, Yu Y, Verma A, Yang H, Colla S, Jia Y, Zheng H, Bohannan Z, Ganan-Gomez I, Futreal A, Takahashi K, Chin L, Kantarjian H, Pellagatti A, Bowman T, Boultwood J, Garcia-Manero G, Wei Y.

Br J Haematol. 2016 Apr;173(1):161-5. doi: 10.1111/bjh.13574. Epub 2015 Jun 24. No abstract available.

9.

Telomerase deficiency delays renal recovery in mice after ischemia-reperfusion injury by impairing autophagy.

Cheng H, Fan X, Lawson WE, Paueksakon P, Harris RC.

Kidney Int. 2015 Jul;88(1):85-94. doi: 10.1038/ki.2015.69. Epub 2015 Mar 11.

10.

The complex pathophysiology of acquired aplastic anaemia.

Zeng Y, Katsanis E.

Clin Exp Immunol. 2015 Jun;180(3):361-70. doi: 10.1111/cei.12605. Epub 2015 Apr 23. Review.

11.

Evaluation of noncytotoxic DNMT1-depleting therapy in patients with myelodysplastic syndromes.

Saunthararajah Y, Sekeres M, Advani A, Mahfouz R, Durkin L, Radivoyevitch T, Englehaupt R, Juersivich J, Cooper K, Husseinzadeh H, Przychodzen B, Rump M, Hobson S, Earl M, Sobecks R, Dean R, Reu F, Tiu R, Hamilton B, Copelan E, Lichtin A, Hsi E, Kalaycio M, Maciejewski J.

J Clin Invest. 2015 Mar 2;125(3):1043-55. doi: 10.1172/JCI78789. Epub 2015 Jan 26.

12.

Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres.

Wang J, Lu X, Sakk V, Klein CA, Rudolph KL.

Blood. 2014 Nov 20;124(22):3237-40. doi: 10.1182/blood-2014-04-568055. Epub 2014 Sep 16.

13.

Acute myeloid leukemia arising from a donor derived premalignant hematopoietic clone: A possible mechanism for the origin of leukemia in donor cells.

Dickson MA, Papadopoulos EB, Hedvat CV, Jhanwar SC, Brentjens RJ.

Leuk Res Rep. 2014 May 20;3(2):38-41. doi: 10.1016/j.lrr.2014.04.001. eCollection 2014.

14.

Bone marrow mesenchymal stem cells from patients with aplastic anemia maintain functional and immune properties and do not contribute to the pathogenesis of the disease.

Bueno C, Roldan M, Anguita E, Romero-Moya D, Martín-Antonio B, Rosu-Myles M, del Cañizo C, Campos F, García R, Gómez-Casares M, Fuster JL, Jurado M, Delgado M, Menendez P.

Haematologica. 2014 Jul;99(7):1168-75. doi: 10.3324/haematol.2014.103580. Epub 2014 Apr 11.

15.

Induction of Chromosomal Instability via Telomere Dysfunction and Epigenetic Alterations in Myeloid Neoplasia.

Vajen B, Thomay K, Schlegelberger B.

Cancers (Basel). 2013 Jul 4;5(3):857-74. doi: 10.3390/cancers5030857.

16.

p16(INK4a) protects against dysfunctional telomere-induced ATR-dependent DNA damage responses.

Wang Y, Sharpless N, Chang S.

J Clin Invest. 2013 Oct;123(10):4489-501. doi: 10.1172/JCI69574. Epub 2013 Sep 16.

17.
18.

Pyrimidine motif triple helix in the Kluyveromyces lactis telomerase RNA pseudoknot is essential for function in vivo.

Cash DD, Cohen-Zontag O, Kim NK, Shefer K, Brown Y, Ulyanov NB, Tzfati Y, Feigon J.

Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):10970-5. doi: 10.1073/pnas.1309590110. Epub 2013 Jun 17.

19.

Lifespan differences in hematopoietic stem cells are due to imperfect repair and unstable mean-reversion.

Sieburg HB, Cattarossi G, Muller-Sieburg CE.

PLoS Comput Biol. 2013 Apr;9(4):e1003006. doi: 10.1371/journal.pcbi.1003006. Epub 2013 Apr 18.

20.

Complement anaphylatoxins C3a and C5a induce a failing regenerative program in cardiac resident cells. Evidence of a role for cardiac resident stem cells other than cardiomyocyte renewal.

Lara-Astiaso D, Izarra A, Estrada JC, Albo C, Moscoso I, Samper E, Moncayo J, Solano A, Bernad A, Díez-Juan A.

Springerplus. 2012 Dec;1(1):63. doi: 10.1186/2193-1801-1-63. Epub 2012 Dec 12.

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