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Optic nerve astrocyte reactivity protects function in experimental glaucoma and other nerve injuries.

Sun D, Moore S, Jakobs TC.

J Exp Med. 2017 May 1;214(5):1411-1430. doi: 10.1084/jem.20160412. Epub 2017 Apr 17.


Neuroprotection for glaucoma: Requirements for clinical translation.

Levin LA, Crowe ME, Quigley HA; Lasker/IRRF Initiative on Astrocytes and Glaucomatous Neurodegeneration Participants..

Exp Eye Res. 2017 Apr;157:34-37. doi: 10.1016/j.exer.2016.12.005. Epub 2016 Dec 9.


Loss of Fractalkine Signaling Exacerbates Axon Transport Dysfunction in a Chronic Model of Glaucoma.

Breen KT, Anderson SR, Steele MR, Calkins DJ, Bosco A, Vetter ML.

Front Neurosci. 2016 Nov 24;10:526. eCollection 2016.


Evaluating retinal ganglion cell loss and dysfunction.

Mead B, Tomarev S.

Exp Eye Res. 2016 Oct;151:96-106. doi: 10.1016/j.exer.2016.08.006. Epub 2016 Aug 12. Review.


Stem Cells in the Trabecular Meshwork for Regulating Intraocular Pressure.

Yun H, Zhou Y, Wills A, Du Y.

J Ocul Pharmacol Ther. 2016 Jun;32(5):253-60. doi: 10.1089/jop.2016.0005. Epub 2016 May 16.


Glial coverage in the optic nerve expands in proportion to optic axon loss in chronic mouse glaucoma.

Bosco A, Breen KT, Anderson SR, Steele MR, Calkins DJ, Vetter ML.

Exp Eye Res. 2016 Sep;150:34-43. doi: 10.1016/j.exer.2016.01.014. Epub 2016 Feb 3.


Early astrocyte redistribution in the optic nerve precedes axonopathy in the DBA/2J mouse model of glaucoma.

Cooper ML, Crish SD, Inman DM, Horner PJ, Calkins DJ.

Exp Eye Res. 2016 Sep;150:22-33. doi: 10.1016/j.exer.2015.11.016. Epub 2015 Dec 2.


Quantitative measurement of retinal ganglion cell populations via histology-based random forest classification.

Hedberg-Buenz A, Christopher MA, Lewis CJ, Fernandes KA, Dutca LM, Wang K, Scheetz TE, Abràmoff MD, Libby RT, Garvin MK, Anderson MG.

Exp Eye Res. 2016 May;146:370-85. doi: 10.1016/j.exer.2015.09.011. Epub 2015 Oct 22.


β-III-Tubulin: a reliable marker for retinal ganglion cell labeling in experimental models of glaucoma.

Jiang SM, Zeng LP, Zeng JH, Tang L, Chen XM, Wei X.

Int J Ophthalmol. 2015 Aug 18;8(4):643-52. doi: 10.3980/j.issn.2222-3959.2015.04.01. eCollection 2015.


RetFM-J, an ImageJ-based module for automated counting and quantifying features of nuclei in retinal whole-mounts.

Hedberg-Buenz A, Christopher MA, Lewis CJ, Meyer KJ, Rudd DS, Dutca LM, Wang K, Garvin MK, Scheetz TE, Abràmoff MD, Harper MM, Anderson MG.

Exp Eye Res. 2016 May;146:386-92. doi: 10.1016/j.exer.2015.07.020. Epub 2015 Aug 14.


Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression.

Lebrun-Julien F, Suter U.

ASN Neuro. 2015 Jun 30;7(3). pii: 1759091415593066. doi: 10.1177/1759091415593066. Print 2015 May-Jun.


In vivo imaging methods to assess glaucomatous optic neuropathy.

Fortune B.

Exp Eye Res. 2015 Dec;141:139-53. doi: 10.1016/j.exer.2015.06.001. Epub 2015 Jun 3. Review.


Tools and resources for analyzing gene expression changes in glaucomatous neurodegeneration.

Nickells RW, Pelzel HR.

Exp Eye Res. 2015 Dec;141:99-110. doi: 10.1016/j.exer.2015.05.009. Epub 2015 May 19. Review.


Elevated intracranial pressure causes optic nerve and retinal ganglion cell degeneration in mice.

Nusbaum DM, Wu SM, Frankfort BJ.

Exp Eye Res. 2015 Jul;136:38-44. doi: 10.1016/j.exer.2015.04.014. Epub 2015 Apr 23.


Transcription Factor Brn-3b Overexpression Enhances Neurite Outgrowth in PC12 Cells Under Condition of Hypoxia.

Phatak NR, Stankowska DL, Krishnamoorthy RR.

Cell Mol Neurobiol. 2015 Aug;35(6):769-83. doi: 10.1007/s10571-015-0171-0. Epub 2015 Mar 19.


Neurodegeneration severity can be predicted from early microglia alterations monitored in vivo in a mouse model of chronic glaucoma.

Bosco A, Romero CO, Breen KT, Chagovetz AA, Steele MR, Ambati BK, Vetter ML.

Dis Model Mech. 2015 May;8(5):443-55. doi: 10.1242/dmm.018788. Epub 2015 Mar 9.


Progressive degeneration of retinal and superior collicular functions in mice with sustained ocular hypertension.

Chen H, Zhao Y, Liu M, Feng L, Puyang Z, Yi J, Liang P, Zhang HF, Cang J, Troy JB, Liu X.

Invest Ophthalmol Vis Sci. 2015 Feb 26;56(3):1971-84. doi: 10.1167/iovs.14-15691.

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