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Items: 12


DNA-PKcs Negatively Regulates Cyclin B1 Protein Stability through Facilitating Its Ubiquitination Mediated by Cdh1-APC/C Pathway.

Shang ZF, Tan W, Liu XD, Yu L, Li B, Li M, Song M, Wang Y, Xiao BB, Zhong CG, Guan H, Zhou PK.

Int J Biol Sci. 2015 Jul 14;11(9):1026-35. doi: 10.7150/ijbs.12443. eCollection 2015.


Depletion of ATR selectively sensitizes ATM-deficient human mammary epithelial cells to ionizing radiation and DNA-damaging agents.

Cui Y, Palii SS, Innes CL, Paules RS.

Cell Cycle. 2014;13(22):3541-50. doi: 10.4161/15384101.2014.960729.


Genome-wide small RNA sequencing and gene expression analysis reveals a microRNA profile of cancer susceptibility in ATM-deficient human mammary epithelial cells.

Hesse JE, Liu L, Innes CL, Cui Y, Palii SS, Paules RS.

PLoS One. 2013 May 31;8(5):e64779. doi: 10.1371/journal.pone.0064779. Print 2013.


Dissecting cellular responses to irradiation via targeted disruptions of the ATM-CHK1-PP2A circuit.

Palii SS, Cui Y, Innes CL, Paules RS.

Cell Cycle. 2013 Apr 1;12(7):1105-18. doi: 10.4161/cc.24127. Epub 2013 Mar 5.


Elevated cyclin G2 expression intersects with DNA damage checkpoint signaling and is required for a potent G2/M checkpoint arrest response to doxorubicin.

Zimmermann M, Arachchige-Don AS, Donaldson MS, Dallapiazza RF, Cowan CE, Horne MC.

J Biol Chem. 2012 Jun 29;287(27):22838-53. doi: 10.1074/jbc.M112.376855. Epub 2012 May 15.


A flexible and qualitatively stable model for cell cycle dynamics including DNA damage effects.

Jeffries CD, Johnson CR, Zhou T, Simpson DA, Kaufmann WK.

Gene Regul Syst Bio. 2012;6:55-66. doi: 10.4137/GRSB.S8476. Epub 2012 Apr 11.


The "Mutated in Colorectal Cancer" Protein Is a Novel Target of the UV-Induced DNA Damage Checkpoint.

Pangon L, Sigglekow ND, Larance M, Al-Sohaily S, Mladenova DN, Selinger CI, Musgrove EA, Kohonen-Corish MR.

Genes Cancer. 2010 Sep;1(9):917-26. doi: 10.1177/1947601910388937.


Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells.

Qi Y, Schoene NW, Lartey FM, Cheng WH.

J Biol Chem. 2010 Oct 22;285(43):33010-7. doi: 10.1074/jbc.M110.137406. Epub 2010 Aug 6.


Revised genetic requirements for the decatenation G2 checkpoint: the role of ATM.

Bower JJ, Zhou Y, Zhou T, Simpson DA, Arlander SJ, Paules RS, Cordeiro-Stone M, Kaufmann WK.

Cell Cycle. 2010 Apr 15;9(8):1617-28. Epub 2010 Apr 15.


Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival.

Fu D, Brophy JA, Chan CT, Atmore KA, Begley U, Paules RS, Dedon PC, Begley TJ, Samson LD.

Mol Cell Biol. 2010 May;30(10):2449-59. doi: 10.1128/MCB.01604-09. Epub 2010 Mar 22.


The human intra-S checkpoint response to UVC-induced DNA damage.

Kaufmann WK.

Carcinogenesis. 2010 May;31(5):751-65. doi: 10.1093/carcin/bgp230. Epub 2009 Sep 30. Review.


Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.

Callén E, Jankovic M, Wong N, Zha S, Chen HT, Difilippantonio S, Di Virgilio M, Heidkamp G, Alt FW, Nussenzweig A, Nussenzweig M.

Mol Cell. 2009 May 15;34(3):285-97. doi: 10.1016/j.molcel.2009.04.025.

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