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miR-502-mediated histone methyltransferase SET8 expression is associated with clear cell renal cell carcinoma risk.

Zhang S, Guo Z, Xu J, Wang J, Zhang J, Cui L, Zhang H, Liu Y, Bai Y.

Oncol Lett. 2017 Dec;14(6):7131-7138. doi: 10.3892/ol.2017.7115. Epub 2017 Oct 2.


DNA Replication Control During Drosophila Development: Insights into the Onset of S Phase, Replication Initiation, and Fork Progression.

Hua BL, Orr-Weaver TL.

Genetics. 2017 Sep;207(1):29-47. doi: 10.1534/genetics.115.186627. Review.


Polo-like kinase 1 (PLK1)-dependent phosphorylation of methylenetetrahydrofolate reductase (MTHFR) regulates replication via histone methylation.

Li X, Nai S, Ding Y, Geng Q, Zhu B, Yu K, Zhu WG, Dong MQ, Su XD, Xu X, Li J.

Cell Cycle. 2017 Oct 18;16(20):1933-1942. doi: 10.1080/15384101.2017.1363942. Epub 2017 Aug 18.


Polymorphism (rs16917496) at the miR-502 Binding Site of the Lysine Methyltransferase 5A (SET8) and Its Correlation with Colorectal Cancer in Iranians.

Mosallayi M, Simonian M, Khosravi S, Salehi AR, Khodadoostan M, Sebghatollahi V, Baradaran A, Salehi R.

Adv Biomed Res. 2017 Jul 14;6:77. doi: 10.4103/2277-9175.210656. eCollection 2017.


Complex Determinants of Epithelial: Mesenchymal Phenotypic Plasticity in Ovarian Cancer.

Klymenko Y, Kim O, Stack MS.

Cancers (Basel). 2017 Aug 9;9(8). pii: E104. doi: 10.3390/cancers9080104. Review.


Histone H4K20 tri-methylation at late-firing origins ensures timely heterochromatin replication.

Brustel J, Kirstein N, Izard F, Grimaud C, Prorok P, Cayrou C, Schotta G, Abdelsamie AF, Déjardin J, Méchali M, Baldacci G, Sardet C, Cadoret JC, Schepers A, Julien E.

EMBO J. 2017 Sep 15;36(18):2726-2741. doi: 10.15252/embj.201796541. Epub 2017 Aug 4.


The PPARγ-SETD8 axis constitutes an epigenetic, p53-independent checkpoint on p21-mediated cellular senescence.

Shih CT, Chang YF, Chen YT, Ma CP, Chen HW, Yang CC, Lu JC, Tsai YS, Chen HC, Tan BC.

Aging Cell. 2017 Aug;16(4):797-813. doi: 10.1111/acel.12607. Epub 2017 May 17.


Cell cycle-dependent degradation of the methyltransferase SETD3 attenuates cell proliferation and liver tumorigenesis.

Cheng X, Hao Y, Shu W, Zhao M, Zhao C, Wu Y, Peng X, Yao P, Xiao D, Qing G, Pan Z, Yin L, Hu D, Du HN.

J Biol Chem. 2017 Jun 2;292(22):9022-9033. doi: 10.1074/jbc.M117.778001. Epub 2017 Apr 25.


SUV4-20 activity in the preimplantation mouse embryo controls timely replication.

Eid A, Rodriguez-Terrones D, Burton A, Torres-Padilla ME.

Genes Dev. 2016 Nov 15;30(22):2513-2526. Epub 2016 Dec 5.


A new layer of degradation mechanism for PR-Set7/Set8 during cell cycle.

Zheng N, Dai X, Wang Z, Wei W.

Cell Cycle. 2016 Nov 16;15(22):3042-3047. Epub 2016 Sep 20.


FLASH protects ZEB1 from degradation and supports cancer cells' epithelial-to-mesenchymal transition.

Abshire CF, Carroll JL, Dragoi AM.

Oncogenesis. 2016 Aug 15;5(8):e254. doi: 10.1038/oncsis.2016.55.


H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex.

Saredi G, Huang H, Hammond CM, Alabert C, Bekker-Jensen S, Forne I, Reverón-Gómez N, Foster BM, Mlejnkova L, Bartke T, Cejka P, Mailand N, Imhof A, Patel DJ, Groth A.

Nature. 2016 Jun 30;534(7609):714-718. doi: 10.1038/nature18312. Epub 2016 Jun 22.


Methylation of histone H4 lysine 20 by PR-Set7 ensures the integrity of late replicating sequence domains in Drosophila.

Li Y, Armstrong RL, Duronio RJ, MacAlpine DM.

Nucleic Acids Res. 2016 Sep 6;44(15):7204-18. doi: 10.1093/nar/gkw333. Epub 2016 Apr 29.


Multivalent Interactions by the Set8 Histone Methyltransferase With Its Nucleosome Substrate.

Girish TS, McGinty RK, Tan S.

J Mol Biol. 2016 Apr 24;428(8):1531-43. doi: 10.1016/j.jmb.2016.02.025. Epub 2016 Mar 4.


Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications.

Serrano-Gomez SJ, Maziveyi M, Alahari SK.

Mol Cancer. 2016 Feb 24;15:18. doi: 10.1186/s12943-016-0502-x. Review.


MMSET is dynamically regulated during cell-cycle progression and promotes normal DNA replication.

Evans DL, Zhang H, Ham H, Pei H, Lee S, Kim J, Billadeau DD, Lou Z.

Cell Cycle. 2016;15(1):95-105. doi: 10.1080/15384101.2015.1121323.


Histone H4 Lysine 20 (H4K20) Methylation, Expanding the Signaling Potential of the Proteome One Methyl Moiety at a Time.

van Nuland R, Gozani O.

Mol Cell Proteomics. 2016 Mar;15(3):755-64. doi: 10.1074/mcp.R115.054742. Epub 2015 Nov 23. Review.


Synthesis of lysine methyltransferase inhibitors.

Hui C, Ye T.

Front Chem. 2015 Jul 23;3:44. doi: 10.3389/fchem.2015.00044. eCollection 2015. Review.


MiRNA inhibition in tissue engineering and regenerative medicine.

Beavers KR, Nelson CE, Duvall CL.

Adv Drug Deliv Rev. 2015 Jul 1;88:123-37. doi: 10.1016/j.addr.2014.12.006. Epub 2014 Dec 29. Review.

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