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Items: 1 to 20 of 33

1.

Natural products as mediators of disease.

Garg N, Luzzatto-Knaan T, Melnik AV, Caraballo-Rodríguez AM, Floros DJ, Petras D, Gregor R, Dorrestein PC, Phelan VV.

Nat Prod Rep. 2017 Feb 1;34(2):194-219. doi: 10.1039/c6np00063k. Epub 2016 Nov 22. Review.

PMID:
27874907
2.

Design, synthesis, and biological evaluation of α-hydroxyacyl-AMS inhibitors of amino acid adenylation enzymes.

Davis TD, Mohandas P, Chiriac MI, Bythrow GV, Quadri LE, Tan DS.

Bioorg Med Chem Lett. 2016 Nov 1;26(21):5340-5345. doi: 10.1016/j.bmcl.2016.09.027. Epub 2016 Sep 16.

PMID:
27692545
3.

Designed Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosa.

Ji C, Sharma I, Pratihar D, Hudson LL, Maura D, Guney T, Rahme LG, Pesci EC, Coleman JP, Tan DS.

ACS Chem Biol. 2016 Nov 18;11(11):3061-3067. Epub 2016 Sep 22.

PMID:
27658001
4.

F420H2 Is Required for Phthiocerol Dimycocerosate Synthesis in Mycobacteria.

Purwantini E, Daniels L, Mukhopadhyay B.

J Bacteriol. 2016 Jul 13;198(15):2020-8. doi: 10.1128/JB.01035-15. Print 2016 Aug 1.

5.

Comparative Genomic Analysis Reveals a Possible Novel Non-Tuberculous Mycobacterium Species with High Pathogenic Potential.

Choo SW, Dutta A, Wong GJ, Wee WY, Ang MY, Siow CC.

PLoS One. 2016 Apr 1;11(4):e0150413. doi: 10.1371/journal.pone.0150413. eCollection 2016.

6.

Pleiotropic consequences of gene knockouts in the phthiocerol dimycocerosate and phenolic glycolipid biosynthetic gene cluster of the opportunistic human pathogen Mycobacterium marinum.

Mohandas P, Budell WC, Mueller E, Au A, Bythrow GV, Quadri LE.

FEMS Microbiol Lett. 2016 Mar;363(5):fnw016. doi: 10.1093/femsle/fnw016. Epub 2016 Jan 26.

7.

Active site-directed proteomic probes for adenylation domains in nonribosomal peptide synthetases.

Konno S, Ishikawa F, Suzuki T, Dohmae N, Burkart MD, Kakeya H.

Chem Commun (Camb). 2015 Feb 11;51(12):2262-5. doi: 10.1039/c4cc09412c.

8.

Biosynthesis of cell envelope-associated phenolic glycolipids in Mycobacterium marinum.

Vergnolle O, Chavadi SS, Edupuganti UR, Mohandas P, Chan C, Zeng J, Kopylov M, Angelo NG, Warren JD, Soll CE, Quadri LE.

J Bacteriol. 2015 Mar;197(6):1040-50. doi: 10.1128/JB.02546-14. Epub 2015 Jan 5.

9.

Genetics of Capsular Polysaccharides and Cell Envelope (Glyco)lipids.

Daffé M, Crick DC, Jackson M.

Microbiol Spectr. 2014;2(4). pii: 14.

10.

Complete genome sequence of producer of the glycopeptide antibiotic Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus of Pseudonocardiaceae.

Rebets Y, Tokovenko B, Lushchyk I, Rückert C, Zaburannyi N, Bechthold A, Kalinowski J, Luzhetskyy A.

BMC Genomics. 2014 Oct 10;15:885. doi: 10.1186/1471-2164-15-885.

11.

General platform for systematic quantitative evaluation of small-molecule permeability in bacteria.

Davis TD, Gerry CJ, Tan DS.

ACS Chem Biol. 2014 Nov 21;9(11):2535-44. doi: 10.1021/cb5003015. Epub 2014 Sep 8.

12.

The mycobacterial cell envelope-lipids.

Jackson M.

Cold Spring Harb Perspect Med. 2014 Aug 7;4(10). pii: a021105. doi: 10.1101/cshperspect.a021105. Review.

13.

The cell envelope glycoconjugates of Mycobacterium tuberculosis.

Angala SK, Belardinelli JM, Huc-Claustre E, Wheat WH, Jackson M.

Crit Rev Biochem Mol Biol. 2014 Sep-Oct;49(5):361-99. doi: 10.3109/10409238.2014.925420. Epub 2014 Jun 10. Review.

14.

4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide (ML267), a potent inhibitor of bacterial phosphopantetheinyl transferase that attenuates secondary metabolism and thwarts bacterial growth.

Foley TL, Rai G, Yasgar A, Daniel T, Baker HL, Attene-Ramos M, Kosa NM, Leister W, Burkart MD, Jadhav A, Simeonov A, Maloney DJ.

J Med Chem. 2014 Feb 13;57(3):1063-78. doi: 10.1021/jm401752p. Epub 2014 Jan 22.

15.

Cyclic AMP-dependent protein lysine acylation in mycobacteria regulates fatty acid and propionate metabolism.

Nambi S, Gupta K, Bhattacharyya M, Ramakrishnan P, Ravikumar V, Siddiqui N, Thomas AT, Visweswariah SS.

J Biol Chem. 2013 May 17;288(20):14114-24. doi: 10.1074/jbc.M113.463992. Epub 2013 Apr 3.

16.

Targeting the mycobacterial envelope for tuberculosis drug development.

Favrot L, Ronning DR.

Expert Rev Anti Infect Ther. 2012 Sep;10(9):1023-36. doi: 10.1586/eri.12.91. Review.

17.

Production of mycobacterial cell wall glycopeptidolipids requires a member of the MbtH-like protein family.

Tatham E, Sundaram Chavadi S, Mohandas P, Edupuganti UR, Angala SK, Chatterjee D, Quadri LE.

BMC Microbiol. 2012 Jun 22;12:118. doi: 10.1186/1471-2180-12-118.

18.

The mycobacterial acyltransferase PapA5 is required for biosynthesis of cell wall-associated phenolic glycolipids.

Chavadi SS, Onwueme KC, Edupuganti UR, Jerome J, Chatterjee D, Soll CE, Quadri LE.

Microbiology. 2012 May;158(Pt 5):1379-87. doi: 10.1099/mic.0.057869-0. Epub 2012 Feb 23.

19.

Both phthiocerol dimycocerosates and phenolic glycolipids are required for virulence of Mycobacterium marinum.

Yu J, Tran V, Li M, Huang X, Niu C, Wang D, Zhu J, Wang J, Gao Q, Liu J.

Infect Immun. 2012 Apr;80(4):1381-9. doi: 10.1128/IAI.06370-11. Epub 2012 Jan 30.

20.

Adenylating enzymes in Mycobacterium tuberculosis as drug targets.

Duckworth BP, Nelson KM, Aldrich CC.

Curr Top Med Chem. 2012;12(7):766-96. Review.

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