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Items: 1 to 20 of 26


Subcellular domain-dependent molecular hierarchy of SFK and FAK in mechanotransduction and cytokine signaling.

Wan Q, TruongVo T, Steele HE, Ozcelikkale A, Han B, Wang Y, Oh J, Yokota H, Na S.

Sci Rep. 2017 Aug 22;7(1):9033. doi: 10.1038/s41598-017-09495-5.


MicroRNA-29b Contributes to Collagens Imbalance in Human Osteoarthritic and Dedifferentiated Articular Chondrocytes.

Moulin D, Salone V, Koufany M, Clément T, Behm-Ansmant I, Branlant C, Charpentier B, Jouzeau JY.

Biomed Res Int. 2017;2017:9792512. doi: 10.1155/2017/9792512. Epub 2017 May 22.


Friction-Induced Mitochondrial Dysregulation Contributes to Joint Deterioration in Prg4 Knockout Mice.

Waller KA, Zhang LX, Jay GD.

Int J Mol Sci. 2017 Jun 11;18(6). pii: E1252. doi: 10.3390/ijms18061252.


Interstitial Perfusion Culture with Specific Soluble Factors Inhibits Type I Collagen Production from Human Osteoarthritic Chondrocytes in Clinical-Grade Collagen Sponges.

Mayer N, Lopa S, Talò G, Lovati AB, Pasdeloup M, Riboldi SA, Moretti M, Mallein-Gerin F.

PLoS One. 2016 Sep 1;11(9):e0161479. doi: 10.1371/journal.pone.0161479. eCollection 2016.


Mechanotransduction in primary human osteoarthritic chondrocytes is mediated by metabolism of energy, lipids, and amino acids.

Zignego DL, Hilmer JK, June RK.

J Biomech. 2015 Dec 16;48(16):4253-61. doi: 10.1016/j.jbiomech.2015.10.038. Epub 2015 Oct 31.


Compression induces Ephrin-A2 in PDL fibroblasts via c-fos.

Sen S, Diercke K, Zingler S, Lux CJ, Erber R.

J Dent Res. 2015 Mar;94(3):464-72. doi: 10.1177/0022034514567197. Epub 2015 Jan 20.


Extracellular and intracellular mechanisms of mechanotransduction in three-dimensionally embedded rat chondrocytes.

Shioji S, Imai S, Ando K, Kumagai K, Matsusue Y.

PLoS One. 2014 Dec 5;9(12):e114327. doi: 10.1371/journal.pone.0114327. eCollection 2014.


Type X collagen levels are elevated in serum from human osteoarthritis patients and associated with biomarkers of cartilage degradation and inflammation.

He Y, Siebuhr AS, Brandt-Hansen NU, Wang J, Su D, Zheng Q, Simonsen O, Petersen KK, Arendt-Nielsen L, Eskehave T, Hoeck HC, Karsdal MA, Bay-Jensen AC.

BMC Musculoskelet Disord. 2014 Sep 22;15:309. doi: 10.1186/1471-2474-15-309.


Runx1 Activities in Superficial Zone Chondrocytes, Osteoarthritic Chondrocyte Clones and Response to Mechanical Loading.

LeBlanc KT, Walcott ME, Gaur T, O'Connell SL, Basil K, Tadiri CP, Mason-Savas A, Silva JA, van Wijnen AJ, Stein JL, Stein GS, Ayers DC, Lian JB, Fanning PJ.

J Cell Physiol. 2015 Feb;230(2):440-8. doi: 10.1002/jcp.24727.


Connexin43 hemichannels mediate small molecule exchange between chondrocytes and matrix in biomechanically-stimulated temporomandibular joint cartilage.

Zhang J, Zhang HY, Zhang M, Qiu ZY, Wu YP, Callaway DA, Jiang JX, Lu L, Jing L, Yang T, Wang MQ.

Osteoarthritis Cartilage. 2014 Jun;22(6):822-30. doi: 10.1016/j.joca.2014.03.017. Epub 2014 Apr 3.


The mechanical microenvironment of high concentration agarose for applying deformation to primary chondrocytes.

Zignego DL, Jutila AA, Gelbke MK, Gannon DM, June RK.

J Biomech. 2014 Jun 27;47(9):2143-8. doi: 10.1016/j.jbiomech.2013.10.051. Epub 2013 Nov 8.


Continuous cyclic mechanical tension increases ank expression in endplate chondrocytes through the TGF-β1 and p38 pathway.

Xu H, Zhang X, Wang H, Zhang Y, Shi Y, Zhang X.

Eur J Histochem. 2013 Sep 25;57(3):e28. doi: 10.4081/ejh.2013.e28.


Homeostatic mechanisms in articular cartilage and role of inflammation in osteoarthritis.

Houard X, Goldring MB, Berenbaum F.

Curr Rheumatol Rep. 2013 Nov;15(11):375. doi: 10.1007/s11926-013-0375-6. Review.


Moderate dynamic compression inhibits pro-catabolic response of cartilage to mechanical injury, tumor necrosis factor-α and interleukin-6, but accentuates degradation above a strain threshold.

Li Y, Frank EH, Wang Y, Chubinskaya S, Huang HH, Grodzinsky AJ.

Osteoarthritis Cartilage. 2013 Dec;21(12):1933-41. doi: 10.1016/j.joca.2013.08.021. Epub 2013 Sep 3.


Rac1 mediates load-driven attenuation of mRNA expression of nerve growth factor beta in cartilage and chondrocytes.

Shim JW, Hamamura K, Chen A, Wan Q, Na S, Yokota H.

J Musculoskelet Neuronal Interact. 2013 Sep;13(3):372-9.


Bioreactors to influence stem cell fate: augmentation of mesenchymal stem cell signaling pathways via dynamic culture systems.

Yeatts AB, Choquette DT, Fisher JP.

Biochim Biophys Acta. 2013 Feb;1830(2):2470-80. doi: 10.1016/j.bbagen.2012.06.007. Epub 2012 Jun 15. Review.


Dynamic compression of chondrocyte-agarose constructs reveals new candidate mechanosensitive genes.

Bougault C, Aubert-Foucher E, Paumier A, Perrier-Groult E, Huot L, Hot D, Duterque-Coquillaud M, Mallein-Gerin F.

PLoS One. 2012;7(5):e36964. doi: 10.1371/journal.pone.0036964. Epub 2012 May 17.


Mechanotransduction and cartilage integrity.

Leong DJ, Hardin JA, Cobelli NJ, Sun HB.

Ann N Y Acad Sci. 2011 Dec;1240:32-7. doi: 10.1111/j.1749-6632.2011.06301.x. Review.


Effects of Wnt3A and mechanical load on cartilage chondrocyte homeostasis.

Thomas RS, Clarke AR, Duance VC, Blain EJ.

Arthritis Res Ther. 2011;13(6):R203. doi: 10.1186/ar3536. Epub 2011 Dec 9.


P2Y(2) receptors and GRK2 are involved in oscillatory fluid flow induced ERK1/2 responses in chondrocytes.

Xing Y, Gu Y, Gomes RR Jr, You J.

J Orthop Res. 2011 Jun;29(6):828-33. doi: 10.1002/jor.21319. Epub 2010 Dec 23.

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