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Items: 1 to 20 of 32


A functional BH3 domain in an aquaporin from Leishmania infantum.

Genes CM, de Lucio H, González VM, Sánchez-Murcia PA, Rico E, Gago F, Fasel N, Jiménez-Ruiz A.

Cell Death Discov. 2016 Jul 4;2:16043. doi: 10.1038/cddiscovery.2016.43. eCollection 2016.


Pro-death activity of a BH3 domain in an aquaporin from the protozoan parasite Leishmania.

Genes CM, de Lucio H, Sánchez-Murcia PA, Gago F, Jiménez-Ruiz A.

Cell Death Dis. 2016 Jul 28;7(7):e2318. doi: 10.1038/cddis.2016.229. No abstract available.


Universal minicircle sequence binding protein of Leishmania donovani regulates pathogenicity by controlling expression of cytochrome-b.

Singh R, Purkait B, Abhishek K, Saini S, Das S, Verma S, Mandal A, Ghosh AK, Ansari Y, Kumar A, Sardar AH, Kumar A, Parrack P, Das P.

Cell Biosci. 2016 Feb 17;6:13. doi: 10.1186/s13578-016-0072-z. eCollection 2016.


Coupling of lysosomal and mitochondrial membrane permeabilization in trypanolysis by APOL1.

Vanwalleghem G, Fontaine F, Lecordier L, Tebabi P, Klewe K, Nolan DP, Yamaryo-Botté Y, Botté C, Kremer A, Burkard GS, Rassow J, Roditi I, Pérez-Morga D, Pays E.

Nat Commun. 2015 Aug 26;6:8078. doi: 10.1038/ncomms9078.


Leishmania infantum EndoG is an endo/exo-nuclease essential for parasite survival.

Rico E, Oliva C, Gutierrez KJ, Alzate JF, Genes CM, Moreno D, Casanova E, Gigante A, Pérez-Pérez MJ, Camarasa MJ, Clos J, Gago F, Jiménez-Ruiz A.

PLoS One. 2014 Feb 26;9(2):e89526. doi: 10.1371/journal.pone.0089526. eCollection 2014.


Deletion of ubiquitin fold modifier protein Ufm1 processing peptidase Ufsp in L. donovani abolishes Ufm1 processing and alters pathogenesis.

Gannavaram S, Davey S, Lakhal-Naouar I, Duncan R, Nakhasi HL.

PLoS Negl Trop Dis. 2014 Feb 20;8(2):e2707. doi: 10.1371/journal.pntd.0002707. eCollection 2014 Feb.


Disuccinyl betulin triggers metacaspase-dependent endonuclease G-mediated cell death in unicellular protozoan parasite Leishmania donovani.

Chowdhury S, Mukherjee T, Chowdhury SR, Sengupta S, Mukhopadhyay S, Jaisankar P, Majumder HK.

Antimicrob Agents Chemother. 2014;58(4):2186-201. doi: 10.1128/AAC.02193-13. Epub 2014 Jan 27.


Aptamer based, non-PCR, non-serological detection of Chagas disease biomarkers in Trypanosoma cruzi infected mice.

Nagarkatti R, de Araujo FF, Gupta C, Debrabant A.

PLoS Negl Trop Dis. 2014 Jan 16;8(1):e2650. doi: 10.1371/journal.pntd.0002650. eCollection 2014.


The first suicides: a legacy inherited by parasitic protozoans from prokaryote ancestors.

Taylor-Brown E, Hurd H.

Parasit Vectors. 2013 Apr 18;6:108. doi: 10.1186/1756-3305-6-108. Review.


Development of an aptamer-based concentration method for the detection of Trypanosoma cruzi in blood.

Nagarkatti R, Bist V, Sun S, Fortes de Araujo F, Nakhasi HL, Debrabant A.

PLoS One. 2012;7(8):e43533. doi: 10.1371/journal.pone.0043533. Epub 2012 Aug 22.


NAD(P)H cytochrome b5 oxidoreductase deficiency in Leishmania major results in impaired linoleate synthesis followed by increased oxidative stress and cell death.

Mukherjee S, Sen Santara S, Das S, Bose M, Roy J, Adak S.

J Biol Chem. 2012 Oct 12;287(42):34992-5003. doi: 10.1074/jbc.M112.389338. Epub 2012 Aug 25.


Programmed cell death in Leishmania: biochemical evidence and role in parasite infectivity.

Gannavaram S, Debrabant A.

Front Cell Infect Microbiol. 2012 Jul 10;2:95. doi: 10.3389/fcimb.2012.00095. eCollection 2012. Review.


Apoptosis and apoptotic mimicry in Leishmania: an evolutionary perspective.

El-Hani CN, Borges VM, Wanderley JL, Barcinski MA.

Front Cell Infect Microbiol. 2012 Jul 12;2:96. doi: 10.3389/fcimb.2012.00096. eCollection 2012. Review.


Deletion of mitochondrial associated ubiquitin fold modifier protein Ufm1 in Leishmania donovani results in loss of β-oxidation of fatty acids and blocks cell division in the amastigote stage.

Gannavaram S, Connelly PS, Daniels MP, Duncan R, Salotra P, Nakhasi HL.

Mol Microbiol. 2012 Oct;86(1):187-98. doi: 10.1111/j.1365-2958.2012.08183.x. Epub 2012 Aug 16.


Identification and characterization of genes involved in leishmania pathogenesis: the potential for drug target selection.

Duncan R, Gannavaram S, Dey R, Debrabant A, Lakhal-Naouar I, Nakhasi HL.

Mol Biol Int. 2011;2011:428486. doi: 10.4061/2011/428486. Epub 2011 Jun 26.


Trypanosomes and the solution to a 50-year mitochondrial calcium mystery.

Docampo R, Lukeš J.

Trends Parasitol. 2012 Jan;28(1):31-7. doi: 10.1016/ Epub 2011 Nov 14. Review.


Plasmodium falciparum metacaspase PfMCA-1 triggers a z-VAD-fmk inhibitable protease to promote cell death.

Meslin B, Beavogui AH, Fasel N, Picot S.

PLoS One. 2011;6(8):e23867. doi: 10.1371/journal.pone.0023867. Epub 2011 Aug 17.


Evolution of apoptosis-like programmed cell death in unicellular protozoan parasites.

Kaczanowski S, Sajid M, Reece SE.

Parasit Vectors. 2011 Mar 25;4:44. doi: 10.1186/1756-3305-4-44. Review.


Endoplasmic reticulum stress-induced apoptosis in Leishmania through Ca2+-dependent and caspase-independent mechanism.

Dolai S, Pal S, Yadav RK, Adak S.

J Biol Chem. 2011 Apr 15;286(15):13638-46. doi: 10.1074/jbc.M110.201889. Epub 2011 Feb 17.

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