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Items: 1 to 20 of 30

1.

Syndecan-1 deficiency promotes tumor growth in a murine model of colitis-induced colon carcinoma.

Binder Gallimidi A, Nussbaum G, Hermano E, Weizman B, Meirovitz A, Vlodavsky I, Götte M, Elkin M.

PLoS One. 2017 Mar 28;12(3):e0174343. doi: 10.1371/journal.pone.0174343. eCollection 2017.

2.

Heparanase: From basic research to therapeutic applications in cancer and inflammation.

Vlodavsky I, Singh P, Boyango I, Gutter-Kapon L, Elkin M, Sanderson RD, Ilan N.

Drug Resist Updat. 2016 Nov;29:54-75. doi: 10.1016/j.drup.2016.10.001. Epub 2016 Oct 6.

PMID:
27912844
3.

Heparanase regulation of cancer, autophagy and inflammation: new mechanisms and targets for therapy.

Sanderson RD, Elkin M, Rapraeger AC, Ilan N, Vlodavsky I.

FEBS J. 2017 Jan;284(1):42-55. doi: 10.1111/febs.13932. Epub 2016 Nov 16. Review.

PMID:
27758044
4.

Cell surface-anchored syndecan-1 ameliorates intestinal inflammation and neutrophil transmigration in ulcerative colitis.

Zhang Y, Wang Z, Liu J, Zhang S, Fei J, Li J, Zhang T, Wang J, Park PW, Chen Y.

J Cell Mol Med. 2017 Jan;21(1):13-25. doi: 10.1111/jcmm.12934. Epub 2016 Aug 25. Erratum in: J Cell Mol Med. 2017 Apr;21(4):834.

5.

Syndecan-1 (CD138) deficiency increases Staphylococcus aureus infection but has no effect on pathology in a mouse model of peritoneal dialysis.

Kowalewska PM, Nguyen UT, Burrows LL, Fox-Robichaud AE.

J Biomed Sci. 2016 Feb 1;23:20. doi: 10.1186/s12929-016-0232-9.

6.

Plasma-Mediated Gut Protection After Hemorrhagic Shock is Lessened in Syndecan-1-/- Mice.

Ban K, Peng Z, Pati S, Witkov RB, Park PW, Kozar RA.

Shock. 2015 Nov;44(5):452-7. doi: 10.1097/SHK.0000000000000452.

7.

High glucose-induced intestinal epithelial barrier damage is aggravated by syndecan-1 destruction and heparanase overexpression.

Qing Q, Zhang S, Chen Y, Li R, Mao H, Chen Q.

J Cell Mol Med. 2015 Jun;19(6):1366-74. doi: 10.1111/jcmm.12523. Epub 2015 Feb 20.

8.

Matrix expansion and syncytial aggregation of syndecan-1+ cells underpin villous atrophy in coeliac disease.

Salvestrini C, Lucas M, Lionetti P, Torrente F, James S, Phillips AD, Murch SH.

PLoS One. 2014 Sep 8;9(9):e106005. doi: 10.1371/journal.pone.0106005. eCollection 2014.

9.

The potential of heparanase as a therapeutic target in cancer.

Pisano C, Vlodavsky I, Ilan N, Zunino F.

Biochem Pharmacol. 2014 May 1;89(1):12-9. doi: 10.1016/j.bcp.2014.02.010. Epub 2014 Feb 22.

10.

Mannose supplements induce embryonic lethality and blindness in phosphomannose isomerase hypomorphic mice.

Sharma V, Nayak J, DeRossi C, Charbono A, Ichikawa M, Ng BG, Grajales-Esquivel E, Srivastava A, Wang L, He P, Scott DA, Russell J, Contreras E, Guess CM, Krajewski S, Del Rio-Tsonis K, Freeze HH.

FASEB J. 2014 Apr;28(4):1854-69. doi: 10.1096/fj.13-245514. Epub 2014 Jan 13.

11.

Central role of the gut epithelial barrier in the pathogenesis of chronic intestinal inflammation: lessons learned from animal models and human genetics.

Pastorelli L, De Salvo C, Mercado JR, Vecchi M, Pizarro TT.

Front Immunol. 2013 Sep 17;4:280. doi: 10.3389/fimmu.2013.00280. Review.

12.

Heparan sulfate on intestinal epithelial cells plays a critical role in intestinal crypt homeostasis via Wnt/β-catenin signaling.

Yamamoto S, Nakase H, Matsuura M, Honzawa Y, Matsumura K, Uza N, Yamaguchi Y, Mizoguchi E, Chiba T.

Am J Physiol Gastrointest Liver Physiol. 2013 Aug 1;305(3):G241-9. doi: 10.1152/ajpgi.00480.2012. Epub 2013 Jun 6.

13.

Versatile role of heparanase in inflammation.

Goldberg R, Meirovitz A, Hirshoren N, Bulvik R, Binder A, Rubinstein AM, Elkin M.

Matrix Biol. 2013 Jun 24;32(5):234-240. doi: 10.1016/j.matbio.2013.02.008. Epub 2013 Mar 13. Review.

14.

Heparanase in inflammation and inflammation-associated cancer.

Meirovitz A, Goldberg R, Binder A, Rubinstein AM, Hermano E, Elkin M.

FEBS J. 2013 May;280(10):2307-19. doi: 10.1111/febs.12184. Epub 2013 Mar 4. Review.

15.

Over-expression of human endosulfatase-1 exacerbates cadmium-induced injury to transformed human lung cells in vitro.

Zhang H, Newman DR, Bonner JC, Sannes PL.

Toxicol Appl Pharmacol. 2012 Nov 15;265(1):27-42. doi: 10.1016/j.taap.2012.09.008. Epub 2012 Sep 19.

16.

Transmembrane and extracellular domains of syndecan-1 have distinct functions in regulating lung epithelial migration and adhesion.

Altemeier WA, Schlesinger SY, Buell CA, Brauer R, Rapraeger AC, Parks WC, Chen P.

J Biol Chem. 2012 Oct 12;287(42):34927-35. doi: 10.1074/jbc.M112.376814. Epub 2012 Aug 30.

17.

Syndecan 1 plays a novel role in enteral glutamine's gut-protective effects of the postischemic gut.

Peng Z, Ban K, Sen A, Grill R, Park P, Costantini TW, Kozar R.

Shock. 2012 Jul;38(1):57-62. doi: 10.1097/SHK.0b013e31825a188a.

18.

Pathophysiological changes to the peritoneal membrane during PD-related peritonitis: the role of mesothelial cells.

Yung S, Chan TM.

Mediators Inflamm. 2012;2012:484167. doi: 10.1155/2012/484167. Epub 2012 Apr 10. Review.

19.

Heparanase affects food intake and regulates energy balance in mice.

Karlsson-Lindahl L, Schmidt L, Haage D, Hansson C, Taube M, Egecioglu E, Tan YX, Admyre T, Jansson JO, Vlodavsky I, Li JP, Lindahl U, Dickson SL.

PLoS One. 2012;7(3):e34313. doi: 10.1371/journal.pone.0034313. Epub 2012 Mar 27. Erratum in: PLoS One. 2012;7(10). doi:10.1371/annotation/c91d94c7-fd12-4a77-ba18-d3ff4f163d72. Egeciouglu, Emil [corrected to Egecioglu, Emil].

20.

Molecular functions of syndecan-1 in disease.

Teng YH, Aquino RS, Park PW.

Matrix Biol. 2012 Jan;31(1):3-16. doi: 10.1016/j.matbio.2011.10.001. Epub 2011 Oct 18. Review.

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