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Structure and Function of the Nuclear Pore Complex Cytoplasmic mRNA Export Platform.

Fernandez-Martinez J, Kim SJ, Shi Y, Upla P, Pellarin R, Gagnon M, Chemmama IE, Wang J, Nudelman I, Zhang W, Williams R, Rice WJ, Stokes DL, Zenklusen D, Chait BT, Sali A, Rout MP.

Cell. 2016 Nov 17;167(5):1215-1228.e25. doi: 10.1016/j.cell.2016.10.028.


Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex.

Schulze-Gahmen U, Echeverria I, Stjepanovic G, Bai Y, Lu H, Schneidman-Duhovny D, Doudna JA, Zhou Q, Sali A, Hurley JH.

Elife. 2016 Oct 12;5. pii: e15910. doi: 10.7554/eLife.15910.


Simple rules for passive diffusion through the nuclear pore complex.

Timney BL, Raveh B, Mironska R, Trivedi JM, Kim SJ, Russel D, Wente SR, Sali A, Rout MP.

J Cell Biol. 2016 Oct 10;215(1):57-76.


Theoretical modeling of multiprotein complexes by iSPOT: Integration of small-angle X-ray scattering, hydroxyl radical footprinting, and computational docking.

Huang W, Ravikumar KM, Parisien M, Yang S.

J Struct Biol. 2016 Dec;196(3):340-349. doi: 10.1016/j.jsb.2016.08.001.


Case study on the evolution of hetero-oligomer interfaces based on the differences in paralogous proteins.

Aoto S, Yura K.

Biophys Physicobiol. 2015 Dec 2;12:103-16. doi: 10.2142/biophysico.12.0_103.


Structure of Complement C3(H2O) Revealed By Quantitative Cross-Linking/Mass Spectrometry And Modeling.

Chen ZA, Pellarin R, Fischer L, Sali A, Nilges M, Barlow PN, Rappsilber J.

Mol Cell Proteomics. 2016 Aug;15(8):2730-43. doi: 10.1074/mcp.M115.056473.


Systematic Protein-Protein Interaction Analysis Reveals Intersubcomplex Contacts in the Nuclear Pore Complex.

Apelt L, Knockenhauer KE, Leksa NC, Benlasfer N, Schwartz TU, Stelzl U.

Mol Cell Proteomics. 2016 Aug;15(8):2594-606. doi: 10.1074/mcp.M115.054627.


Principles and Overview of Sampling Methods for Modeling Macromolecular Structure and Dynamics.

Maximova T, Moffatt R, Ma B, Nussinov R, Shehu A.

PLoS Comput Biol. 2016 Apr 28;12(4):e1004619. doi: 10.1371/journal.pcbi.1004619. Review.


Revealing Higher Order Protein Structure Using Mass Spectrometry.

Chait BT, Cadene M, Olinares PD, Rout MP, Shi Y.

J Am Soc Mass Spectrom. 2016 Jun;27(6):952-65. doi: 10.1007/s13361-016-1385-1.


Ion Mobility-Mass Spectrometry Analysis of Cross-Linked Intact Multiprotein Complexes: Enhanced Gas-Phase Stabilities and Altered Dissociation Pathways.

Samulak BM, Niu S, Andrews PC, Ruotolo BT.

Anal Chem. 2016 May 17;88(10):5290-8. doi: 10.1021/acs.analchem.6b00518.


Fimbrin phosphorylation by metaphase Cdk1 regulates actin cable dynamics in budding yeast.

Miao Y, Han X, Zheng L, Xie Y, Mu Y, Yates JR 3rd, Drubin DG.

Nat Commun. 2016 Apr 12;7:11265. doi: 10.1038/ncomms11265.


The Evolving Contribution of Mass Spectrometry to Integrative Structural Biology.

Faini M, Stengel F, Aebersold R.

J Am Soc Mass Spectrom. 2016 Jun;27(6):966-74. doi: 10.1007/s13361-016-1382-4.


Structure of γ-tubulin small complex based on a cryo-EM map, chemical cross-links, and a remotely related structure.

Greenberg CH, Kollman J, Zelter A, Johnson R, MacCoss MJ, Davis TN, Agard DA, Sali A.

J Struct Biol. 2016 Jun;194(3):303-10. doi: 10.1016/j.jsb.2016.03.006.


Population-based 3D genome structure analysis reveals driving forces in spatial genome organization.

Tjong H, Li W, Kalhor R, Dai C, Hao S, Gong K, Zhou Y, Li H, Zhou XJ, Le Gros MA, Larabell CA, Chen L, Alber F.

Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):E1663-72. doi: 10.1073/pnas.1512577113.


Deciphering the Structure and Function of Nuclear Pores Using Single-Molecule Fluorescence Approaches.

Musser SM, Grünwald D.

J Mol Biol. 2016 May 22;428(10 Pt A):2091-119. doi: 10.1016/j.jmb.2016.02.023. Review.


Energetics of Transport through the Nuclear Pore Complex.

Ghavami A, van der Giessen E, Onck PR.

PLoS One. 2016 Feb 19;11(2):e0148876. doi: 10.1371/journal.pone.0148876.


Interactome Mapping Reveals the Evolutionary History of the Nuclear Pore Complex.

Obado SO, Brillantes M, Uryu K, Zhang W, Ketaren NE, Chait BT, Field MC, Rout MP.

PLoS Biol. 2016 Feb 18;14(2):e1002365. doi: 10.1371/journal.pbio.1002365.


Structure Determination of the Nuclear Pore Complex with Three-Dimensional Cryo electron Microscopy.

von Appen A, Beck M.

J Mol Biol. 2016 May 22;428(10 Pt A):2001-10. doi: 10.1016/j.jmb.2016.01.004. Review.


Posttranslational marks control architectural and functional plasticity of the nuclear pore complex basket.

Niño CA, Guet D, Gay A, Brutus S, Jourquin F, Mendiratta S, Salamero J, Géli V, Dargemont C.

J Cell Biol. 2016 Jan 18;212(2):167-80. doi: 10.1083/jcb.201506130.


Nucleoporin's Like Charge Regions Are Major Regulators of FG Coverage and Dynamics Inside the Nuclear Pore Complex.

Peyro M, Soheilypour M, Ghavami A, Mofrad MR.

PLoS One. 2015 Dec 11;10(12):e0143745. doi: 10.1371/journal.pone.0143745.

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