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Items: 1 to 20 of 116

1.

DDX6 Represses Aberrant Activation of Interferon-Stimulated Genes.

Lumb JH, Li Q, Popov LM, Ding S, Keith MT, Merrill BD, Greenberg HB, Li JB, Carette JE.

Cell Rep. 2017 Jul 25;20(4):819-831. doi: 10.1016/j.celrep.2017.06.085.

2.

DNA repair and systemic lupus erythematosus.

Meas R, Burak MJ, Sweasy JB.

DNA Repair (Amst). 2017 Aug;56:174-182. doi: 10.1016/j.dnarep.2017.06.020. Epub 2017 Jun 9. Review.

PMID:
28623091
3.

DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity.

Vanpouille-Box C, Alard A, Aryankalayil MJ, Sarfraz Y, Diamond JM, Schneider RJ, Inghirami G, Coleman CN, Formenti SC, Demaria S.

Nat Commun. 2017 Jun 9;8:15618. doi: 10.1038/ncomms15618.

4.

Immune Diseases Associated with TREX1 and STING Dysfunction.

Yan N.

J Interferon Cytokine Res. 2017 May;37(5):198-206. doi: 10.1089/jir.2016.0086.

PMID:
28475463
5.

Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion.

Luthra P, Aguirre S, Yen BC, Pietzsch CA, Sanchez-Aparicio MT, Tigabu B, Morlock LK, García-Sastre A, Leung DW, Williams NS, Fernandez-Sesma A, Bukreyev A, Basler CF.

MBio. 2017 Apr 4;8(2). pii: e00368-17. doi: 10.1128/mBio.00368-17.

6.

RAD51 interconnects between DNA replication, DNA repair and immunity.

Bhattacharya S, Srinivasan K, Abdisalaam S, Su F, Raj P, Dozmorov I, Mishra R, Wakeland EK, Ghose S, Mukherjee S, Asaithamby A.

Nucleic Acids Res. 2017 May 5;45(8):4590-4605. doi: 10.1093/nar/gkx126.

7.

Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion.

Li P, Du J, Goodier JL, Hou J, Kang J, Kazazian HH Jr, Zhao K, Yu XF.

Nucleic Acids Res. 2017 May 5;45(8):4619-4631. doi: 10.1093/nar/gkx178.

8.

A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1.

Erdal E, Haider S, Rehwinkel J, Harris AL, McHugh PJ.

Genes Dev. 2017 Feb 15;31(4):353-369. doi: 10.1101/gad.289769.116. Epub 2017 Mar 9.

9.

MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment.

Wilson R, Espinosa-Diez C, Kanner N, Chatterjee N, Ruhl R, Hipfinger C, Advani SJ, Li J, Khan OF, Franovic A, Weis SM, Kumar S, Coussens LM, Anderson DG, Chen CC, Cheresh DA, Anand S.

Nat Commun. 2016 Nov 25;7:13597. doi: 10.1038/ncomms13597.

10.

DNA Damage: From Chronic Inflammation to Age-Related Deterioration.

Ioannidou A, Goulielmaki E, Garinis GA.

Front Genet. 2016 Oct 25;7:187. eCollection 2016. Review.

11.

DNA sensor cGAS-mediated immune recognition.

Xia P, Wang S, Gao P, Gao G, Fan Z.

Protein Cell. 2016 Nov;7(11):777-791. Epub 2016 Sep 30. Review.

12.

Insights from Mendelian Interferonopathies: Comparison of CANDLE, SAVI with AGS, Monogenic Lupus.

Kim H, Sanchez GA, Goldbach-Mansky R.

J Mol Med (Berl). 2016 Oct;94(10):1111-1127. Epub 2016 Sep 27. Review.

PMID:
27678529
13.

p53 in the game of transposons.

Wylie A, Jones AE, Abrams JM.

Bioessays. 2016 Nov;38(11):1111-1116. doi: 10.1002/bies.201600115. Epub 2016 Sep 19.

PMID:
27644006
14.

Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations.

Stam AH, Kothari PH, Shaikh A, Gschwendter A, Jen JC, Hodgkinson S, Hardy TA, Hayes M, Kempster PA, Kotschet KE, Bajema IM, van Duinen SG, Maat-Schieman ML, de Jong PT, de Smet MD, de Wolff-Rouendaal D, Dijkman G, Pelzer N, Kolar GR, Schmidt RE, Lacey J, Joseph D, Fintak DR, Grand MG, Brunt EM, Liapis H, Hajj-Ali RA, Kruit MC, van Buchem MA, Dichgans M, Frants RR, van den Maagdenberg AM, Haan J, Baloh RW, Atkinson JP, Terwindt GM, Ferrari MD.

Brain. 2016 Sep 6. pii: aww217. [Epub ahead of print]

PMID:
27604306
15.

DNA Damage Response and Immune Defense: Links and Mechanisms.

Nakad R, Schumacher B.

Front Genet. 2016 Aug 9;7:147. doi: 10.3389/fgene.2016.00147. eCollection 2016. Review.

16.

Taking the STING out of TLR-driven autoimmune diseases: good, bad, or indifferent?

Pawaria S, Sharma S, Baum R, Nündel K, Busto P, Gravallese EM, Fitzgerald KA, Marshak-Rothstein A.

J Leukoc Biol. 2017 Jan;101(1):121-126. doi: 10.1189/jlb.3MR0316-115R. Epub 2016 Aug 16. Review.

PMID:
27531928
17.

Upregulated LINE-1 Activity in the Fanconi Anemia Cancer Susceptibility Syndrome Leads to Spontaneous Pro-inflammatory Cytokine Production.

Brégnard C, Guerra J, Déjardin S, Passalacqua F, Benkirane M, Laguette N.

EBioMedicine. 2016 Jun;8:184-94. doi: 10.1016/j.ebiom.2016.05.005. Epub 2016 May 6.

18.

RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA.

Wolf C, Rapp A, Berndt N, Staroske W, Schuster M, Dobrick-Mattheuer M, Kretschmer S, König N, Kurth T, Wieczorek D, Kast K, Cardoso MC, Günther C, Lee-Kirsch MA.

Nat Commun. 2016 May 27;7:11752. doi: 10.1038/ncomms11752.

19.

DNA polymerase-α regulates the activation of type I interferons through cytosolic RNA:DNA synthesis.

Starokadomskyy P, Gemelli T, Rios JJ, Xing C, Wang RC, Li H, Pokatayev V, Dozmorov I, Khan S, Miyata N, Fraile G, Raj P, Xu Z, Xu Z, Ma L, Lin Z, Wang H, Yang Y, Ben-Amitai D, Orenstein N, Mussaffi H, Baselga E, Tadini G, Grunebaum E, Sarajlija A, Krzewski K, Wakeland EK, Yan N, de la Morena MT, Zinn AR, Burstein E.

Nat Immunol. 2016 May;17(5):495-504. doi: 10.1038/ni.3409. Epub 2016 Mar 28.

20.

Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.

Mackenzie KJ, Carroll P, Lettice L, Tarnauskaitė Ž, Reddy K, Dix F, Revuelta A, Abbondati E, Rigby RE, Rabe B, Kilanowski F, Grimes G, Fluteau A, Devenney PS, Hill RE, Reijns MA, Jackson AP.

EMBO J. 2016 Apr 15;35(8):831-44. doi: 10.15252/embj.201593339. Epub 2016 Feb 22.

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