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Items: 1 to 20 of 21


Environmental Immunology: Lessons Learned from Exposure to a Select Panel of Immunotoxicants.

Kreitinger JM, Beamer CA, Shepherd DM.

J Immunol. 2016 Apr 15;196(8):3217-25. doi: 10.4049/jimmunol.1502149. Review.


Immunomodulation By Subchronic Low Dose 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in Experimental Autoimmune Encephalomyelitis in the Absence of Pertussis Toxin.

Yang EJ, Stokes JV, Kummari E, Eells J, Kaplan BL.

Toxicol Sci. 2016 May;151(1):35-43. doi: 10.1093/toxsci/kfw020. Epub 2016 Jan 27.


A Birth Cohort Study of Maternal and Infant Serum PCB-153 and DDE Concentrations and Responses to Infant Tuberculosis Vaccination.

Jusko TA, De Roos AJ, Lee SY, Thevenet-Morrison K, Schwartz SM, Verner MA, Murinova LP, Drobná B, Kočan A, Fabišiková A, Čonka K, Trnovec T, Hertz-Picciotto I, Lawrence BP.

Environ Health Perspect. 2016 Jun;124(6):813-21. doi: 10.1289/ehp.1510101. Epub 2015 Dec 9.


Effects of Developmental Activation of the Aryl Hydrocarbon Receptor by 2,3,7,8-Tetrachlorodibenzo-p-dioxin on Long-term Self-renewal of Murine Hematopoietic Stem Cells.

Laiosa MD, Tate ER, Ahrenhoerster LS, Chen Y, Wang D.

Environ Health Perspect. 2016 Jul;124(7):957-65. doi: 10.1289/ehp.1509820. Epub 2015 Oct 23.


Developmental Activation of the AHR Increases Effector CD4+ T Cells and Exacerbates Symptoms in Autoimmune Disease-Prone Gnaq+/- Mice.

Boule LA, Burke CG, Fenton BM, Thevenet-Morrison K, Jusko TA, Lawrence BP.

Toxicol Sci. 2015 Dec;148(2):555-66. doi: 10.1093/toxsci/kfv203. Epub 2015 Sep 11.


Fetal Hematopoietic Stem Cells Are the Canaries in the Coal Mine That Portend Later Life Immune Deficiency.

Laiosa MD, Tate ER.

Endocrinology. 2015 Oct;156(10):3458-65. doi: 10.1210/en.2015-1347. Epub 2015 Aug 4. Review.


Activation of the aryl hydrocarbon receptor during development enhances the pulmonary CD4+ T-cell response to viral infection.

Boule LA, Winans B, Lambert K, Vorderstrasse BA, Topham DJ, Pavelka MS Jr, Lawrence BP.

Am J Physiol Lung Cell Mol Physiol. 2015 Aug 1;309(3):L305-13. doi: 10.1152/ajplung.00135.2015. Epub 2015 Jun 12.


Linking the aryl hydrocarbon receptor with altered DNA methylation patterns and developmentally induced aberrant antiviral CD8+ T cell responses.

Winans B, Nagari A, Chae M, Post CM, Ko CI, Puga A, Kraus WL, Lawrence BP.

J Immunol. 2015 May 1;194(9):4446-57. doi: 10.4049/jimmunol.1402044. Epub 2015 Mar 25.


Developmental exposure to 2,3,7,8 tetrachlorodibenzo-p-dioxin attenuates later-life Notch1-mediated T cell development and leukemogenesis.

Ahrenhoerster LS, Leuthner TC, Tate ER, Lakatos PA, Laiosa MD.

Toxicol Appl Pharmacol. 2015 Mar 1;283(2):99-108. doi: 10.1016/j.taap.2014.12.017. Epub 2015 Jan 10.


Effects of developmental activation of the AhR on CD4+ T-cell responses to influenza virus infection in adult mice.

Boule LA, Winans B, Lawrence BP.

Environ Health Perspect. 2014 Nov;122(11):1201-8. doi: 10.1289/ehp.1408110. Epub 2014 Jul 22.


Developmental exposure to 2,3,7,8 tetrachlorodibenzo-p-dioxin attenuates capacity of hematopoietic stem cells to undergo lymphocyte differentiation.

Ahrenhoerster LS, Tate ER, Lakatos PA, Wang X, Laiosa MD.

Toxicol Appl Pharmacol. 2014 Jun 1;277(2):172-82. doi: 10.1016/j.taap.2014.03.020. Epub 2014 Apr 4.


The effects of maternal exposure to bisphenol A on allergic lung inflammation into adulthood.

Bauer SM, Roy A, Emo J, Chapman TJ, Georas SN, Lawrence BP.

Toxicol Sci. 2012 Nov;130(1):82-93. doi: 10.1093/toxsci/kfs227. Epub 2012 Jul 21.


Maternal and early postnatal polychlorinated biphenyl exposure in relation to total serum immunoglobulin concentrations in 6-month-old infants.

Jusko TA, De Roos AJ, Schwartz SM, Lawrence BP, Palkovicova L, Nemessanyi T, Drobna B, Fabisikova A, Kocan A, Jahnova E, Kavanagh TJ, Trnovec T, Hertz-Picciotto I.

J Immunotoxicol. 2011 Jan-Mar;8(1):95-100. doi: 10.3109/1547691X.2010.549096.


Environmental toxicants and the developing immune system: a missing link in the global battle against infectious disease?

Winans B, Humble MC, Lawrence BP.

Reprod Toxicol. 2011 Apr;31(3):327-36. doi: 10.1016/j.reprotox.2010.09.004. Epub 2010 Sep 22. Review.


Breaking patterns of environmentally influenced disease for health risk reduction: immune perspectives.

Dietert RR, DeWitt JC, Germolec DR, Zelikoff JT.

Environ Health Perspect. 2010 Aug;118(8):1091-9. doi: 10.1289/ehp.1001971. Epub 2010 May 18. Review.


Dioxin-induced changes in epididymal sperm count and spermatogenesis.

Foster WG, Maharaj-Briceño S, Cyr DG.

Environ Health Perspect. 2010 Apr;118(4):458-64. doi: 10.1289/ehp.0901084. Review.


Identification of stage-specific gene modulation during early thymocyte development by whole-genome profiling analysis after aryl hydrocarbon receptor activation.

Laiosa MD, Mills JH, Lai ZW, Singh KP, Middleton FA, Gasiewicz TA, Silverstone AE.

Mol Pharmacol. 2010 May;77(5):773-83. doi: 10.1124/mol.109.062497. Epub 2010 Feb 16.


Evidence for ligand-mediated selective modulation of aryl hydrocarbon receptor activity.

Murray IA, Morales JL, Flaveny CA, Dinatale BC, Chiaro C, Gowdahalli K, Amin S, Perdew GH.

Mol Pharmacol. 2010 Feb;77(2):247-54. doi: 10.1124/mol.109.061788. Epub 2009 Nov 10.


Gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin disrupts B-cell lymphopoiesis and exacerbates autoimmune disease in 24-week-old SNF1 mice.

Mustafa A, Holladay SD, Witonsky S, Zimmerman K, Reilly CM, Sponenberg DP, Weinstein DA, Karpuzoglu E, Gogal RM Jr.

Toxicol Sci. 2009 Nov;112(1):133-43. doi: 10.1093/toxsci/kfp177. Epub 2009 Aug 10.


Developmental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters postnatal T cell phenotypes and T cell function and exacerbates autoimmune lupus in 24-week-old SNF1 mice.

Mustafa A, Holladay SD, Goff M, Witonsky S, Kerr R, Weinstein DA, Karpuzoglu-Belgin E, Gogal RM Jr.

Birth Defects Res A Clin Mol Teratol. 2009 Oct;85(10):828-36. doi: 10.1002/bdra.20603.

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