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Items: 1 to 20 of 41

1.

Assessment of safety, efficacy, and dosimetry of a novel 18-kDa translocator protein ligand, [11C]CB184, in healthy human volunteers.

Sakata M, Ishibashi K, Imai M, Wagatsuma K, Ishii K, Hatano K, Ishiwata K, Toyohara J.

EJNMMI Res. 2017 Dec;7(1):26. doi: 10.1186/s13550-017-0271-6. Epub 2017 Mar 23.

2.

11C-ER176, a Radioligand for 18-kDa Translocator Protein, Has Adequate Sensitivity to Robustly Image All Three Affinity Genotypes in Human Brain.

Ikawa M, Lohith TG, Shrestha S, Telu S, Zoghbi SS, Castellano S, Taliani S, Da Settimo F, Fujita M, Pike VW, Innis RB; Biomarkers Consortium Radioligand Project Team.

J Nucl Med. 2017 Feb;58(2):320-325. doi: 10.2967/jnumed.116.178996. Epub 2016 Nov 17.

3.

Glial activation colocalizes with structural abnormalities in amyotrophic lateral sclerosis.

Alshikho MJ, Zürcher NR, Loggia ML, Cernasov P, Chonde DB, Izquierdo Garcia D, Yasek JE, Akeju O, Catana C, Rosen BR, Cudkowicz ME, Hooker JM, Atassi N.

Neurology. 2016 Dec 13;87(24):2554-2561. Epub 2016 Nov 11.

4.

Neuroinflammatory component of gray matter pathology in multiple sclerosis.

Herranz E, Giannì C, Louapre C, Treaba CA, Govindarajan ST, Ouellette R, Loggia ML, Sloane JA, Madigan N, Izquierdo-Garcia D, Ward N, Mangeat G, Granberg T, Klawiter EC, Catana C, Hooker JM, Taylor N, Ionete C, Kinkel RP, Mainero C.

Ann Neurol. 2016 Nov;80(5):776-790. doi: 10.1002/ana.24791. Epub 2016 Oct 25.

PMID:
27686563
5.

Radiation Dosimetry of a Novel Adenosine A2A Receptor Radioligand [11C]Preladenant Based on PET/CT Imaging and Ex Vivo Biodistribution in Rats.

Zhou X, Elsinga PH, Khanapur S, Dierckx RA, de Vries EF, de Jong JR.

Mol Imaging Biol. 2017 Apr;19(2):289-297. doi: 10.1007/s11307-016-0992-3.

6.

Neuroimaging of translocator protein in patients with systemic lupus erythematosus: a pilot study using [11C]DPA-713 positron emission tomography.

Wang Y, Coughlin JM, Ma S, Endres CJ, Kassiou M, Sawa A, Dannals RF, Petri M, Pomper MG.

Lupus. 2016 Jul 6. pii: 0961203316657432. [Epub ahead of print]

PMID:
27387599
7.

Improved Automated Radiosynthesis of [(11)C]PBR28.

Solingapuram Sai KK, Gage D, Nader M, Mach RH, Mintz A.

Sci Pharm. 2015 Jun 19;83(3):413-27. doi: 10.3797/scipharm.1505-06. Print 2015 Jul-Sep.

8.

Radiation dosimetry and biodistribution in non-human primates of the sodium/iodide PET ligand [(18)F]-tetrafluoroborate.

Marti-Climent JM, Collantes M, Jauregui-Osoro M, Quincoces G, Prieto E, Bilbao I, Ecay M, Richter JA, Peñuelas I.

EJNMMI Res. 2015 Dec;5(1):70. doi: 10.1186/s13550-015-0148-5. Epub 2015 Dec 3.

9.

ALS biomarkers for therapy development: State of the field and future directions.

Benatar M, Boylan K, Jeromin A, Rutkove SB, Berry J, Atassi N, Bruijn L.

Muscle Nerve. 2016 Feb;53(2):169-82. doi: 10.1002/mus.24979. Epub 2015 Dec 29. Review.

10.

Lack of neuroinflammation in the HIV-1 transgenic rat: an [(18)F]-DPA714 PET imaging study.

Lee DE, Yue X, Ibrahim WG, Lentz MR, Peterson KL, Jagoda EM, Kassiou M, Maric D, Reid WC, Hammoud DA.

J Neuroinflammation. 2015 Sep 17;12:171. doi: 10.1186/s12974-015-0390-9.

11.

GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP.

Ramanan VK, Risacher SL, Nho K, Kim S, Shen L, McDonald BC, Yoder KK, Hutchins GD, West JD, Tallman EF, Gao S, Foroud TM, Farlow MR, De Jager PL, Bennett DA, Aisen PS, Petersen RC, Jack CR Jr, Toga AW, Green RC, Jagust WJ, Weiner MW, Saykin AJ; Alzheimer’s Disease Neuroimaging Initiative (ADNI).

Brain. 2015 Oct;138(Pt 10):3076-88. doi: 10.1093/brain/awv231. Epub 2015 Aug 11.

12.

[18F]FEBMP: Positron Emission Tomography Imaging of TSPO in a Model of Neuroinflammation in Rats, and in vitro Autoradiograms of the Human Brain.

Tiwari AK, Ji B, Yui J, Fujinaga M, Yamasaki T, Xie L, Luo R, Shimoda Y, Kumata K, Zhang Y, Hatori A, Maeda J, Higuchi M, Wang F, Zhang MR.

Theranostics. 2015 May 26;5(9):961-9. doi: 10.7150/thno.12027. eCollection 2015.

13.

Utility of (18) F-FDG and (11)C-PBR28 microPET for the assessment of rat aortic aneurysm inflammation.

English SJ, Diaz JA, Shao X, Gordon D, Bevard M, Su G, Henke PK, Rogers VE, Upchurch GR, Piert M.

EJNMMI Res. 2014 Dec;4(1):20. doi: 10.1186/s13550-014-0020-z. Epub 2014 May 10.

14.

Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: assessed with [(11)C]-PBR28.

Zürcher NR, Loggia ML, Lawson R, Chonde DB, Izquierdo-Garcia D, Yasek JE, Akeju O, Catana C, Rosen BR, Cudkowicz ME, Hooker JM, Atassi N.

Neuroimage Clin. 2015 Jan 19;7:409-14. doi: 10.1016/j.nicl.2015.01.009. eCollection 2015.

15.

Evidence for brain glial activation in chronic pain patients.

Loggia ML, Chonde DB, Akeju O, Arabasz G, Catana C, Edwards RR, Hill E, Hsu S, Izquierdo-Garcia D, Ji RR, Riley M, Wasan AD, Zürcher NR, Albrecht DS, Vangel MG, Rosen BR, Napadow V, Hooker JM.

Brain. 2015 Mar;138(Pt 3):604-15. doi: 10.1093/brain/awu377. Epub 2015 Jan 12.

16.

Comparison of standardized uptake values with volume of distribution for quantitation of [(11)C]PBR28 brain uptake.

Yoder KK, Territo PR, Hutchins GD, Hannestad J, Morris ED, Gallezot JD, Normandin MD, Cosgrove KP.

Nucl Med Biol. 2015 Mar;42(3):305-8. doi: 10.1016/j.nucmedbio.2014.11.003. Epub 2014 Nov 15.

17.

Purinergic system dysfunction in mood disorders: a key target for developing improved therapeutics.

Ortiz R, Ulrich H, Zarate CA Jr, Machado-Vieira R.

Prog Neuropsychopharmacol Biol Psychiatry. 2015 Mar 3;57:117-31. doi: 10.1016/j.pnpbp.2014.10.016. Epub 2014 Nov 7. Review.

18.

Development of (18)F-labeled radiotracers for neuroreceptor imaging with positron emission tomography.

Brust P, van den Hoff J, Steinbach J.

Neurosci Bull. 2014 Oct;30(5):777-811. doi: 10.1007/s12264-014-1460-6. Epub 2014 Aug 29. Review.

19.

Radiation dosimetry and biodistribution of the translocator protein radiotracer [(11)C]DAA1106 determined with PET/CT in healthy human volunteers.

Brody AL, Okita K, Shieh J, Liang L, Hubert R, Mamoun M, Farahi J, Mandelkern MA.

Nucl Med Biol. 2014 Nov-Dec;41(10):871-5. doi: 10.1016/j.nucmedbio.2014.07.004. Epub 2014 Aug 1.

20.

Tracking neuroinflammation in Alzheimer's disease: the role of positron emission tomography imaging.

Zimmer ER, Leuzy A, Benedet AL, Breitner J, Gauthier S, Rosa-Neto P.

J Neuroinflammation. 2014 Jul 8;11:120. doi: 10.1186/1742-2094-11-120. Review.

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