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Items: 1 to 20 of 23


Histone deacetylase inhibitors mediate DNA damage repair in ameliorating hemorrhagic cystitis.

Haldar S, Dru C, Mishra R, Tripathi M, Duong F, Angara B, Fernandez A, Arditi M, Bhowmick NA.

Sci Rep. 2016 Dec 20;6:39257. doi: 10.1038/srep39257.


Oxidized Guanine Base Lesions Function in 8-Oxoguanine DNA Glycosylase-1-mediated Epigenetic Regulation of Nuclear Factor κB-driven Gene Expression.

Pan L, Zhu B, Hao W, Zeng X, Vlahopoulos SA, Hazra TK, Hegde ML, Radak Z, Bacsi A, Brasier AR, Ba X, Boldogh I.

J Biol Chem. 2016 Dec 2;291(49):25553-25566. Epub 2016 Oct 18.


Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents Atherosclerosis.

Tumurkhuu G, Shimada K, Dagvadorj J, Crother TR, Zhang W, Luthringer D, Gottlieb RA, Chen S, Arditi M.

Circ Res. 2016 Sep 2;119(6):e76-90. doi: 10.1161/CIRCRESAHA.116.308362. Epub 2016 Jul 6.


8-Oxoguanine DNA glycosylase1-driven DNA repair-A paradoxical role in lung aging.

German P, Saenz D, Szaniszlo P, Aguilera-Aguirre L, Pan L, Hegde ML, Bacsi A, Hajas G, Radak Z, Ba X, Mitra S, Papaconstantinou J, Boldogh I.

Mech Ageing Dev. 2017 Jan;161(Pt A):51-65. doi: 10.1016/j.mad.2016.06.009. Epub 2016 Jun 21.


Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation.

Chakraborty A, Wakamiya M, Venkova-Canova T, Pandita RK, Aguilera-Aguirre L, Sarker AH, Singh DK, Hosoki K, Wood TG, Sharma G, Cardenas V, Sarkar PS, Sur S, Pandita TK, Boldogh I, Hazra TK.

J Biol Chem. 2015 Oct 9;290(41):24636-48. doi: 10.1074/jbc.M115.658146. Epub 2015 Aug 5.


OGG1 Involvement in High Glucose-Mediated Enhancement of Bupivacaine-Induced Oxidative DNA Damage in SH-SY5Y Cells.

Liu ZJ, Zhao W, Zhang QG, Li L, Lai LY, Jiang S, Xu SY.

Oxid Med Cell Longev. 2015;2015:683197. doi: 10.1155/2015/683197. Epub 2015 Jun 16.


ATP Depletion Via Mitochondrial F1F0 Complex by Lethal Factor is an Early Event in B. Anthracis-Induced Sudden Cell Death.

Woodberry MW, Aguilera-Aguirre L, Bacsi A, Chopra AK, Kurosky A, Peterson JW, Boldogh I.

J Cell Death. 2009 Aug 27;2:25-39. eCollection 2009.


Innate inflammation induced by the 8-oxoguanine DNA glycosylase-1-KRAS-NF-κB pathway.

Aguilera-Aguirre L, Bacsi A, Radak Z, Hazra TK, Mitra S, Sur S, Brasier AR, Ba X, Boldogh I.

J Immunol. 2014 Nov 1;193(9):4643-53. doi: 10.4049/jimmunol.1401625. Epub 2014 Sep 29.


8-oxoguanine DNA glycosylase-1 augments proinflammatory gene expression by facilitating the recruitment of site-specific transcription factors.

Ba X, Bacsi A, Luo J, Aguilera-Aguirre L, Zeng X, Radak Z, Brasier AR, Boldogh I.

J Immunol. 2014 Mar 1;192(5):2384-94. doi: 10.4049/jimmunol.1302472. Epub 2014 Jan 31.


Alteration of mitochondrial function and insulin sensitivity in primary mouse skeletal muscle cells isolated from transgenic and knockout mice: role of ogg1.

Yuzefovych LV, Schuler AM, Chen J, Alvarez DF, Eide L, Ledoux SP, Wilson GL, Rachek LI.

Endocrinology. 2013 Aug;154(8):2640-9. doi: 10.1210/en.2013-1076. Epub 2013 Jun 7.


8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1.

Hajas G, Bacsi A, Aguilera-Aguirre L, Hegde ML, Tapas KH, Sur S, Radak Z, Ba X, Boldogh I.

Free Radic Biol Med. 2013 Aug;61:384-94. doi: 10.1016/j.freeradbiomed.2013.04.011. Epub 2013 Apr 21.


Active transcriptomic and proteomic reprogramming in the C. elegans nucleotide excision repair mutant xpa-1.

Arczewska KD, Tomazella GG, Lindvall JM, Kassahun H, Maglioni S, Torgovnick A, Henriksson J, Matilainen O, Marquis BJ, Nelson BC, Jaruga P, Babaie E, Holmberg CI, Bürglin TR, Ventura N, Thiede B, Nilsen H.

Nucleic Acids Res. 2013 May 1;41(10):5368-81. doi: 10.1093/nar/gkt225. Epub 2013 Apr 10.


Molecular basis of asbestos-induced lung disease.

Liu G, Cheresh P, Kamp DW.

Annu Rev Pathol. 2013 Jan 24;8:161-87. doi: 10.1146/annurev-pathol-020712-163942. Review.


Oxidative stress and pulmonary fibrosis.

Cheresh P, Kim SJ, Tulasiram S, Kamp DW.

Biochim Biophys Acta. 2013 Jul;1832(7):1028-40. doi: 10.1016/j.bbadis.2012.11.021. Epub 2012 Dec 5. Review.


Down-regulation of 8-oxoguanine DNA glycosylase 1 expression in the airway epithelium ameliorates allergic lung inflammation.

Bacsi A, Aguilera-Aguirre L, Szczesny B, Radak Z, Hazra TK, Sur S, Ba X, Boldogh I.

DNA Repair (Amst). 2013 Jan 1;12(1):18-26. doi: 10.1016/j.dnarep.2012.10.002. Epub 2012 Nov 3.


Biochemical identification of a hydroperoxide derivative of the free 8-oxo-7,8-dihydroguanine base.

Hajas G, Bacsi A, Aguilerra-Aguirre L, German P, Radak Z, Sur S, Hazra TK, Boldogh I.

Free Radic Biol Med. 2012 Feb 15;52(4):749-56. doi: 10.1016/j.freeradbiomed.2011.11.015. Epub 2011 Dec 1.


8-Oxoguanine-DNA glycosylase 1 deficiency modifies allergic airway inflammation by regulating STAT6 and IL-4 in cells and in mice.

Li G, Yuan K, Yan C, Fox J 3rd, Gaid M, Breitwieser W, Bansal AK, Zeng H, Gao H, Wu M.

Free Radic Biol Med. 2012 Jan 15;52(2):392-401. doi: 10.1016/j.freeradbiomed.2011.10.490. Epub 2011 Nov 3.


Combined exercise and insulin-like growth factor-1 supplementation induces neurogenesis in old rats, but do not attenuate age-associated DNA damage.

Koltai E, Zhao Z, Lacza Z, Cselenyak A, Vacz G, Nyakas C, Boldogh I, Ichinoseki-Sekine N, Radak Z.

Rejuvenation Res. 2011 Dec;14(6):585-96. doi: 10.1089/rej.2011.1178. Epub 2011 Aug 25.


Age-dependent changes in 8-oxoguanine-DNA glycosylase activity are modulated by adaptive responses to physical exercise in human skeletal muscle.

Radak Z, Bori Z, Koltai E, Fatouros IG, Jamurtas AZ, Douroudos II, Terzis G, Nikolaidis MG, Chatzinikolaou A, Sovatzidis A, Kumagai S, Naito H, Boldogh I.

Free Radic Biol Med. 2011 Jul 15;51(2):417-23. doi: 10.1016/j.freeradbiomed.2011.04.018. Epub 2011 Apr 15.


8-Oxo-7,8-dihydroguanine: links to gene expression, aging, and defense against oxidative stress.

Radak Z, Boldogh I.

Free Radic Biol Med. 2010 Aug 15;49(4):587-96. doi: 10.1016/j.freeradbiomed.2010.05.008. Epub 2010 May 17.

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