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Genome-wide analysis of gene expression and protein secretion of Babesia canis during virulent infection identifies potential pathogenicity factors.

Eichenberger RM, Ramakrishnan C, Russo G, Deplazes P, Hehl AB.

Sci Rep. 2017 Jun 13;7(1):3357. doi: 10.1038/s41598-017-03445-x.


A Glycosylphosphatidylinositol-Anchored Carbonic Anhydrase-Related Protein of Toxoplasma gondii Is Important for Rhoptry Biogenesis and Virulence.

Chasen NM, Asady B, Lemgruber L, Vommaro RC, Kissinger JC, Coppens I, Moreno SNJ.

mSphere. 2017 May 17;2(3). pii: e00027-17. doi: 10.1128/mSphere.00027-17. eCollection 2017 May-Jun.


An in vitro model of intestinal infection reveals a developmentally regulated transcriptome of Toxoplasma sporozoites and a NF-κB-like signature in infected host cells.

Guiton PS, Sagawa JM, Fritz HM, Boothroyd JC.

PLoS One. 2017 Mar 31;12(3):e0173018. doi: 10.1371/journal.pone.0173018. eCollection 2017.


Functional Characterization of Rhoptry Kinome in the Virulent Toxoplasma gondii RH Strain.

Wang JL, Li TT, Elsheikha HM, Chen K, Zhu WN, Yue DM, Zhu XQ, Huang SY.

Front Microbiol. 2017 Jan 24;8:84. doi: 10.3389/fmicb.2017.00084. eCollection 2017.


Review of Experimental Compounds Demonstrating Anti-Toxoplasma Activity.

McFarland MM, Zach SJ, Wang X, Potluri LP, Neville AJ, Vennerstrom JL, Davis PH.

Antimicrob Agents Chemother. 2016 Nov 21;60(12):7017-7034. Print 2016 Dec. Review.


Reassessing the mechanics of parasite motility and host-cell invasion.

Tardieux I, Baum J.

J Cell Biol. 2016 Aug 29;214(5):507-15. doi: 10.1083/jcb.201605100. Review.


Nucleotide-binding oligomerization domain-containing protein 2 prompts potent inflammatory stimuli during Neospora caninum infection.

Davoli-Ferreira M, Fonseca DM, Mota CM, Dias MS, Lima-Junior DS, da Silva MV, Quirino GF, Zamboni DS, Silva JS, Mineo TW.

Sci Rep. 2016 Jul 5;6:29289. doi: 10.1038/srep29289.


The Rhoptry Pseudokinase ROP54 Modulates Toxoplasma gondii Virulence and Host GBP2 Loading.

Kim EW, Nadipuram SM, Tetlow AL, Barshop WD, Liu PT, Wohlschlegel JA, Bradley PJ.

mSphere. 2016 Mar 23;1(2). pii: e00045-16. doi: 10.1128/mSphere.00045-16. eCollection 2016 Mar-Apr.


DNA vaccination with a gene encoding Toxoplasma gondii Rhoptry Protein 17 induces partial protective immunity against lethal challenge in mice.

Wang HL, Wang YJ, Pei YJ, Bai JZ, Yin LT, Guo R, Yin GR.

Parasite. 2016;23:4. doi: 10.1051/parasite/2016004. Epub 2016 Feb 3.


Induction of interferon-stimulated genes by IRF3 promotes replication of Toxoplasma gondii.

Majumdar T, Chattopadhyay S, Ozhegov E, Dhar J, Goswami R, Sen GC, Barik S.

PLoS Pathog. 2015 Mar 26;11(3):e1004779. doi: 10.1371/journal.ppat.1004779. eCollection 2015 Mar.


Neospora caninum Recruits Host Cell Structures to Its Parasitophorous Vacuole and Salvages Lipids from Organelles.

Nolan SJ, Romano JD, Luechtefeld T, Coppens I.

Eukaryot Cell. 2015 May;14(5):454-73. doi: 10.1128/EC.00262-14. Epub 2015 Mar 6.


Comparative transcriptomics reveals striking similarities between the bovine and feline isolates of Tritrichomonas foetus: consequences for in silico drug-target identification.

Morin-Adeline V, Lomas R, O'Meally D, Stack C, Conesa A, Šlapeta J.

BMC Genomics. 2014 Nov 5;15:955. doi: 10.1186/1471-2164-15-955.


Evaluation of immuno-efficacy of a novel DNA vaccine encoding Toxoplasma gondii rhoptry protein 38 (TgROP38) against chronic toxoplasmosis in a murine model.

Xu Y, Zhang NZ, Tan QD, Chen J, Lu J, Xu QM, Zhu XQ.

BMC Infect Dis. 2014 Sep 30;14:525. doi: 10.1186/1471-2334-14-525.


Partial protective effect of intranasal immunization with recombinant Toxoplasma gondii rhoptry protein 17 against toxoplasmosis in mice.

Wang HL, Zhang TE, Yin LT, Pang M, Guan L, Liu HL, Zhang JH, Meng XL, Bai JZ, Zheng GP, Yin GR.

PLoS One. 2014 Sep 25;9(9):e108377. doi: 10.1371/journal.pone.0108377. eCollection 2014.


Evidence of intraflagellar transport and apical complex formation in a free-living relative of the apicomplexa.

Portman N, Foster C, Walker G, Šlapeta J.

Eukaryot Cell. 2014 Jan;13(1):10-20. doi: 10.1128/EC.00155-13. Epub 2013 Sep 20.


CD4+ T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection.

Kugler DG, Mittelstadt PR, Ashwell JD, Sher A, Jankovic D.

J Exp Med. 2013 Sep 23;210(10):1919-27. doi: 10.1084/jem.20122300. Epub 2013 Aug 26.


Identification and real-time expression analysis of selected Toxoplasma gondii in-vivo induced antigens recognized by IgG and IgM in sera of acute toxoplasmosis patients.

Amerizadeh A, Khoo BY, Teh AY, Golkar M, Abdul Karim IZ, Osman S, Yunus MH, Noordin R.

BMC Infect Dis. 2013 Jun 24;13:287. doi: 10.1186/1471-2334-13-287.


Structural and evolutionary adaptation of rhoptry kinases and pseudokinases, a family of coccidian virulence factors.

Talevich E, Kannan N.

BMC Evol Biol. 2013 Jun 6;13:117. doi: 10.1186/1471-2148-13-117.


Toxoplasma gondii myosin F, an essential motor for centrosomes positioning and apicoplast inheritance.

Jacot D, Daher W, Soldati-Favre D.

EMBO J. 2013 Jun 12;32(12):1702-16. doi: 10.1038/emboj.2013.113. Epub 2013 May 21.


A HT/PEXEL motif in Toxoplasma dense granule proteins is a signal for protein cleavage but not export into the host cell.

Hsiao CH, Luisa Hiller N, Haldar K, Knoll LJ.

Traffic. 2013 May;14(5):519-31. doi: 10.1111/tra.12049. Epub 2013 Feb 26.

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