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DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions.

Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo F, Meadows S, Montoya NR, Herrera NG, Domingos AI, Rastinejad F, Myers RM, Fuller-Pace FV, Bonneau R, Chang HY, Acuto O, Littman DR.

Nature. 2015 Dec 24;528(7583):517-22. doi: 10.1038/nature16193. Epub 2015 Dec 16. Erratum in: Nature. 2016 May 5;533(7601):130. Rigo, Frank W [Corrected to Rigo, Frank]..


Signaling-mediated regulation of MicroRNA processing.

Shen J, Hung MC.

Cancer Res. 2015 Mar 1;75(5):783-91. doi: 10.1158/0008-5472.CAN-14-2568. Epub 2015 Feb 6. Review.


P68 RNA helicase as a molecular target for cancer therapy.

Dai TY, Cao L, Yang ZC, Li YS, Tan L, Ran XZ, Shi CM.

J Exp Clin Cancer Res. 2014 Aug 24;33:64. doi: 10.1186/s13046-014-0064-y. Review.


DDX5 facilitates HIV-1 replication as a cellular co-factor of Rev.

Zhou X, Luo J, Mills L, Wu S, Pan T, Geng G, Zhang J, Luo H, Liu C, Zhang H.

PLoS One. 2013 May 31;8(5):e65040. doi: 10.1371/journal.pone.0065040. Print 2013.


DEAD box RNA helicase functions in cancer.

Fuller-Pace FV.

RNA Biol. 2013 Jan;10(1):121-32. doi: 10.4161/rna.23312. Epub 2013 Jan 1. Review.


DDX5 is a positive regulator of oncogenic NOTCH1 signaling in T cell acute lymphoblastic leukemia.

Lin S, Tian L, Shen H, Gu Y, Li JL, Chen Z, Sun X, You MJ, Wu L.

Oncogene. 2013 Oct;32(40):4845-53. doi: 10.1038/onc.2012.482. Epub 2012 Oct 29.


p68 RNA helicase promotes glioma cell proliferation in vitro and in vivo via direct regulation of NF-κB transcription factor p50.

Wang R, Jiao Z, Li R, Yue H, Chen L.

Neuro Oncol. 2012 Sep;14(9):1116-24. doi: 10.1093/neuonc/nos131. Epub 2012 Jul 18.


Quantitative proteomic analysis of human embryonic stem cell differentiation by 8-plex iTRAQ labelling.

Jadaliha M, Lee HJ, Pakzad M, Fathi A, Jeong SK, Cho SY, Baharvand H, Paik YK, Salekdeh GH.

PLoS One. 2012;7(6):e38532. doi: 10.1371/journal.pone.0038532. Epub 2012 Jun 18.


Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility.

van der Deen M, Akech J, Lapointe D, Gupta S, Young DW, Montecino MA, Galindo M, Lian JB, Stein JL, Stein GS, van Wijnen AJ.

J Biol Chem. 2012 Feb 10;287(7):4503-17. doi: 10.1074/jbc.M111.287771. Epub 2011 Dec 9.


RNA helicase DDX5 is a p53-independent target of ARF that participates in ribosome biogenesis.

Saporita AJ, Chang HC, Winkeler CL, Apicelli AJ, Kladney RD, Wang J, Townsend RR, Michel LS, Weber JD.

Cancer Res. 2011 Nov 1;71(21):6708-17. doi: 10.1158/0008-5472.CAN-11-1472. Epub 2011 Sep 21.


MicroRNA in Cancer: The Involvement of Aberrant MicroRNA Biogenesis Regulatory Pathways.

Davis-Dusenbery BN, Hata A.

Genes Cancer. 2010 Nov;1(11):1100-14. doi: 10.1177/1947601910396213.


An evolutionarily conserved, alternatively spliced, intron in the p68/DDX5 DEAD-box RNA helicase gene encodes a novel miRNA.

Moore HC, Johnston M, Nicol SM, Bourdon JC, Thompson AM, Hutvagner G, Fuller-Pace FV.

RNA. 2011 Apr;17(4):555-62. doi: 10.1261/rna.2591611. Epub 2011 Feb 23.


Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility.

Leong DT, Lim J, Goh X, Pratap J, Pereira BP, Kwok HS, Nathan SS, Dobson JR, Lian JB, Ito Y, Voorhoeve PM, Stein GS, Salto-Tellez M, Cool SM, van Wijnen AJ.

Breast Cancer Res. 2010;12(5):R89. doi: 10.1186/bcr2762. Epub 2010 Oct 28.


Mechanisms of control of microRNA biogenesis.

Davis-Dusenbery BN, Hata A.

J Biochem. 2010 Oct;148(4):381-92. doi: 10.1093/jb/mvq096. Epub 2010 Sep 9. Review.


The RNA helicase p68 modulates expression and function of the Δ133 isoform(s) of p53, and is inversely associated with Δ133p53 expression in breast cancer.

Moore HC, Jordan LB, Bray SE, Baker L, Quinlan PR, Purdie CA, Thompson AM, Bourdon JC, Fuller-Pace FV.

Oncogene. 2010 Dec 9;29(49):6475-84. doi: 10.1038/onc.2010.381. Epub 2010 Sep 6.


The Ewing's sarcoma fusion protein, EWS-FLI, binds Runx2 and blocks osteoblast differentiation.

Li X, McGee-Lawrence ME, Decker M, Westendorf JJ.

J Cell Biochem. 2010 Nov 1;111(4):933-43. doi: 10.1002/jcb.22782.


TEThered to Runx: novel binding partners for runx factors.

Li X, Decker M, Westendorf JJ.

Blood Cells Mol Dis. 2010 Jun 15;45(1):82-5. doi: 10.1016/j.bcmd.2010.03.002. Epub 2010 Apr 1.


A DDX5 S480A polymorphism is associated with increased transcription of fibrogenic genes in hepatic stellate cells.

Guo J, Hong F, Loke J, Yea S, Lim CL, Lee U, Mann DA, Walsh MJ, Sninsky JJ, Friedman SL.

J Biol Chem. 2010 Feb 19;285(8):5428-37. doi: 10.1074/jbc.M109.035295. Epub 2009 Dec 17.


Disruption of mouse corneal epithelial differentiation by conditional inactivation of pnn.

Joo JH, Kim YH, Dunn NW, Sugrue SP.

Invest Ophthalmol Vis Sci. 2010 Apr;51(4):1927-34. doi: 10.1167/iovs.09-4591. Epub 2009 Nov 5.

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