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Items: 1 to 20 of 98

1.

Evidence of stress in β cells obtained with laser capture microdissection from pancreases of brain dead donors.

Ebrahimi A, Jung MH, Dreyfuss JM, Pan H, Sgroi D, Bonner-Weir S, Weir GC.

Islets. 2017 Mar 4;9(2):19-29. doi: 10.1080/19382014.2017.1283083.

PMID:
28252345
2.

PLIN2 is a Key Regulator of the Unfolded Protein Response and Endoplasmic Reticulum Stress Resolution in Pancreatic β Cells.

Chen E, Tsai TH, Li L, Saha P, Chan L, Chang BH.

Sci Rep. 2017 Jan 19;7:40855. doi: 10.1038/srep40855.

3.

MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic β-Cells.

Grieco FA, Sebastiani G, Juan-Mateu J, Villate O, Marroqui L, Ladrière L, Tugay K, Regazzi R, Bugliani M, Marchetti P, Dotta F, Eizirik DL.

Diabetes. 2017 Jan;66(1):100-112. doi: 10.2337/db16-0592.

PMID:
27737950
4.

A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure.

Baron M, Veres A, Wolock SL, Faust AL, Gaujoux R, Vetere A, Ryu JH, Wagner BK, Shen-Orr SS, Klein AM, Melton DA, Yanai I.

Cell Syst. 2016 Oct 26;3(4):346-360.e4. doi: 10.1016/j.cels.2016.08.011.

5.

Thrombospondin 1 protects pancreatic β-cells from lipotoxicity via the PERK-NRF2 pathway.

Cunha DA, Cito M, Carlsson PO, Vanderwinden JM, Molkentin JD, Bugliani M, Marchetti P, Eizirik DL, Cnop M.

Cell Death Differ. 2016 Dec;23(12):1995-2006. doi: 10.1038/cdd.2016.89.

PMID:
27588705
6.

Ubiquitin D Regulates IRE1α/c-Jun N-terminal Kinase (JNK) Protein-dependent Apoptosis in Pancreatic Beta Cells.

Brozzi F, Gerlo S, Grieco FA, Juusola M, Balhuizen A, Lievens S, Gysemans C, Bugliani M, Mathieu C, Marchetti P, Tavernier J, Eizirik DL.

J Biol Chem. 2016 Jun 3;291(23):12040-56. doi: 10.1074/jbc.M115.704619.

PMID:
27044747
7.

Human Lineage-Specific Transcriptional Regulation through GA-Binding Protein Transcription Factor Alpha (GABPa).

Perdomo-Sabogal A, Nowick K, Piccini I, Sudbrak R, Lehrach H, Yaspo ML, Warnatz HJ, Querfurth R.

Mol Biol Evol. 2016 May;33(5):1231-44. doi: 10.1093/molbev/msw007.

8.

Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes.

Cinti F, Bouchi R, Kim-Muller JY, Ohmura Y, Sandoval PR, Masini M, Marselli L, Suleiman M, Ratner LE, Marchetti P, Accili D.

J Clin Endocrinol Metab. 2016 Mar;101(3):1044-54. doi: 10.1210/jc.2015-2860.

9.

Multi‑transgenic minipig models exhibiting potential for hepatic insulin resistance and pancreatic apoptosis.

Kong S, Ruan J, Xin L, Fan J, Xia J, Liu Z, Mu Y, Yang S, Li K.

Mol Med Rep. 2016 Jan;13(1):669-80. doi: 10.3892/mmr.2015.4582.

10.

Experimental study of the protective effects of SYVN1 against diabetic retinopathy.

Yang S, He H, Ma QS, Zhang Y, Zhu Y, Wan X, Wang FW, Wang SS, Liu L, Li B.

Sci Rep. 2015 Sep 11;5:14036. doi: 10.1038/srep14036.

11.

Continuum model of T-cell avidity: Understanding autoreactive and regulatory T-cell responses in type 1 diabetes.

Jaberi-Douraki M, Pietropaolo M, Khadra A.

J Theor Biol. 2015 Oct 21;383:93-105. doi: 10.1016/j.jtbi.2015.07.032.

12.

A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and Microcephaly.

Abdulkarim B, Nicolino M, Igoillo-Esteve M, Daures M, Romero S, Philippi A, Senée V, Lopes M, Cunha DA, Harding HP, Derbois C, Bendelac N, Hattersley AT, Eizirik DL, Ron D, Cnop M, Julier C.

Diabetes. 2015 Nov;64(11):3951-62. doi: 10.2337/db15-0477.

13.

Pancreatic α Cells are Resistant to Metabolic Stress-induced Apoptosis in Type 2 Diabetes.

Marroqui L, Masini M, Merino B, Grieco FA, Millard I, Dubois C, Quesada I, Marchetti P, Cnop M, Eizirik DL.

EBioMedicine. 2015 Mar 17;2(5):378-85. doi: 10.1016/j.ebiom.2015.03.012.

14.

Metabolomics applied to the pancreatic islet.

Gooding JR, Jensen MV, Newgard CB.

Arch Biochem Biophys. 2016 Jan 1;589:120-30. doi: 10.1016/j.abb.2015.06.013. Review.

15.

Loss-of-Function Mutations in APPL1 in Familial Diabetes Mellitus.

Prudente S, Jungtrakoon P, Marucci A, Ludovico O, Buranasupkajorn P, Mazza T, Hastings T, Milano T, Morini E, Mercuri L, Bailetti D, Mendonca C, Alberico F, Basile G, Romani M, Miccinilli E, Pizzuti A, Carella M, Barbetti F, Pascarella S, Marchetti P, Trischitta V, Di Paola R, Doria A.

Am J Hum Genet. 2015 Jul 2;97(1):177-85. doi: 10.1016/j.ajhg.2015.05.011.

16.

Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cells.

Marroqui L, Lopes M, dos Santos RS, Grieco FA, Roivainen M, Richardson SJ, Morgan NG, Op de Beeck A, Eizirik DL.

Elife. 2015 Jun 10;4:e06990. doi: 10.7554/eLife.06990.

17.

Type 2 diabetes as a protein misfolding disease.

Mukherjee A, Morales-Scheihing D, Butler PC, Soto C.

Trends Mol Med. 2015 Jul;21(7):439-49. doi: 10.1016/j.molmed.2015.04.005. Review.

18.

Mechanistic insights into pancreatic beta-cell mass regulation by glucose and free fatty acids.

Oh YS.

Anat Cell Biol. 2015 Mar;48(1):16-24. doi: 10.5115/acb.2015.48.1.16. Review.

19.

The class I histone deacetylase inhibitor MS-275 prevents pancreatic beta cell death induced by palmitate.

Plaisance V, Rolland L, Gmyr V, Annicotte JS, Kerr-Conte J, Pattou F, Abderrahmani A.

J Diabetes Res. 2014;2014:195739. doi: 10.1155/2014/195739.

20.

Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes.

Sun J, Cui J, He Q, Chen Z, Arvan P, Liu M.

Mol Aspects Med. 2015 Apr;42:105-18. doi: 10.1016/j.mam.2015.01.001. Review.

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