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In Situ Pluripotency Factor Expression Promotes Functional Recovery From Cerebral Ischemia.

Seo JH, Lee MY, Yu JH, Kim MS, Song M, Seo CH, Kim HH, Cho SR.

Mol Ther. 2016 Sep;24(9):1538-49. doi: 10.1038/mt.2016.124. Epub 2016 Jun 22.


Human glia can both induce and rescue aspects of disease phenotype in Huntington disease.

Benraiss A, Wang S, Herrlinger S, Li X, Chandler-Militello D, Mauceri J, Burm HB, Toner M, Osipovitch M, Jim Xu Q, Ding F, Wang F, Kang N, Kang J, Curtin PC, Brunner D, Windrem MS, Munoz-Sanjuan I, Nedergaard M, Goldman SA.

Nat Commun. 2016 Jun 7;7:11758. doi: 10.1038/ncomms11758.


Stem and Progenitor Cell-Based Therapy of the Central Nervous System: Hopes, Hype, and Wishful Thinking.

Goldman SA.

Cell Stem Cell. 2016 Feb 4;18(2):174-88. doi: 10.1016/j.stem.2016.01.012. Review.


Increased Olfactory Bulb BDNF Expression Does Not Rescue Deficits in Olfactory Neurogenesis in the Huntington's Disease R6/2 Mouse.

Smail S, Bahga D, McDole B, Guthrie K.

Chem Senses. 2016 Mar;41(3):221-32. doi: 10.1093/chemse/bjv076. Epub 2016 Jan 18.


Adult neurogenesis in neurodegenerative diseases.

Winner B, Winkler J.

Cold Spring Harb Perspect Biol. 2015 Apr 1;7(4):a021287. doi: 10.1101/cshperspect.a021287. Review.


HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity.

Mattis VB, Tom C, Akimov S, Saeedian J, Ƙstergaard ME, Southwell AL, Doty CN, Ornelas L, Sahabian A, Lenaeus L, Mandefro B, Sareen D, Arjomand J, Hayden MR, Ross CA, Svendsen CN.

Hum Mol Genet. 2015 Jun 1;24(11):3257-71. doi: 10.1093/hmg/ddv080. Epub 2015 Mar 3.


Amitriptyline improves motor function via enhanced neurotrophin signaling and mitochondrial functions in the murine N171-82Q Huntington disease model.

Cong WN, Chadwick W, Wang R, Daimon CM, Cai H, Amma J, Wood WH 3rd, Becker KG, Martin B, Maudsley S.

J Biol Chem. 2015 Jan 30;290(5):2728-43. doi: 10.1074/jbc.M114.588608. Epub 2014 Dec 11.


BDNF signaling and survival of striatal neurons.

Baydyuk M, Xu B.

Front Cell Neurosci. 2014 Aug 28;8:254. doi: 10.3389/fncel.2014.00254. eCollection 2014. Review.


Use of Genetically Altered Stem Cells for the Treatment of Huntington's Disease.

Crane AT, Rossignol J, Dunbar GL.

Brain Sci. 2014 Mar 24;4(1):202-19. doi: 10.3390/brainsci4010202.


In vivo reprogramming of astrocytes to neuroblasts in the adult brain.

Niu W, Zang T, Zou Y, Fang S, Smith DK, Bachoo R, Zhang CL.

Nat Cell Biol. 2013 Oct;15(10):1164-75. doi: 10.1038/ncb2843. Epub 2013 Sep 22.


Sustained mobilization of endogenous neural progenitors delays disease progression in a transgenic model of Huntington's disease.

Benraiss A, Toner MJ, Xu Q, Bruel-Jungerman E, Rogers EH, Wang F, Economides AN, Davidson BL, Kageyama R, Nedergaard M, Goldman SA.

Cell Stem Cell. 2013 Jun 6;12(6):787-99. doi: 10.1016/j.stem.2013.04.014.


Striatal oligodendrogliogenesis and neuroblast recruitment are increased in the R6/2 mouse model of Huntington's disease.

McCollum MH, Leon RT, Rush DB, Guthrie KM, Wei J.

Brain Res. 2013 Jun 26;1518:91-103. doi: 10.1016/j.brainres.2013.04.030. Epub 2013 Apr 25.


Extensive changes in DNA methylation are associated with expression of mutant huntingtin.

Ng CW, Yildirim F, Yap YS, Dalin S, Matthews BJ, Velez PJ, Labadorf A, Housman DE, Fraenkel E.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2354-9. doi: 10.1073/pnas.1221292110. Epub 2013 Jan 22.


Testosterone modulation of angiogenesis and neurogenesis in the adult songbird brain.

Chen Z, Ye R, Goldman SA.

Neuroscience. 2013 Jun 3;239:139-48. doi: 10.1016/j.neuroscience.2012.12.043. Epub 2013 Jan 3. Review.


Mouse models of polyglutamine diseases in therapeutic approaches: review and data table. Part II.

Switonski PM, Szlachcic WJ, Gabka A, Krzyzosiak WJ, Figiel M.

Mol Neurobiol. 2012 Oct;46(2):430-66. doi: 10.1007/s12035-012-8316-3. Epub 2012 Sep 4. Review.


The dynamic role of bone morphogenetic proteins in neural stem cell fate and maturation.

Bond AM, Bhalala OG, Kessler JA.

Dev Neurobiol. 2012 Jul;72(7):1068-84. doi: 10.1002/dneu.22022. Review.


Rapid transgene expression in multiple precursor cell types of adult rat subventricular zone mediated by adeno-associated type 1 vectors.

Bockstael O, Melas C, Pythoud C, Levivier M, McCarty D, Samulski RJ, De Witte O, Tenenbaum L.

Hum Gene Ther. 2012 Jul;23(7):742-53. doi: 10.1089/hum.2011.216. Epub 2012 Jun 5.


Nucleic Acid-Based Therapy Approaches for Huntington's Disease.

Vagner T, Young D, Mouravlev A.

Neurol Res Int. 2012;2012:358370. doi: 10.1155/2012/358370. Epub 2012 Jan 11.


Perivascular instruction of cell genesis and fate in the adult brain.

Goldman SA, Chen Z.

Nat Neurosci. 2011 Oct 26;14(11):1382-9. doi: 10.1038/nn.2963. Review.

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