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Items: 1 to 20 of 357

1.

Glioblastoma cancer stem cell lines express functional acid sensing ion channels ASIC1a and ASIC3.

Tian Y, Bresenitz P, Reska A, El Moussaoui L, Beier CP, Gründer S.

Sci Rep. 2017 Oct 20;7(1):13674. doi: 10.1038/s41598-017-13666-9.

2.

Acid-Sensing Ion Channels as Potential Therapeutic Targets in Neurodegeneration and Neuroinflammation.

Ortega-Ramírez A, Vega R, Soto E.

Mediators Inflamm. 2017;2017:3728096. doi: 10.1155/2017/3728096. Epub 2017 Sep 19. Review.

3.

Current-direction/amplitude-dependent single channel gating kinetics of mouse pannexin 1 channel: a new concept for gating kinetics.

Nomura T, Taruno A, Shiraishi M, Nakahari T, Inui T, Sokabe M, Eaton DC, Marunaka Y.

Sci Rep. 2017 Sep 5;7(1):10512. doi: 10.1038/s41598-017-10921-x.

4.

Regulation of the epithelial Na+ channel by paraoxonase-2.

Shi S, Buck TM, Kinlough CL, Marciszyn AL, Hughey RP, Chalfie M, Brodsky JL, Kleyman TR.

J Biol Chem. 2017 Sep 22;292(38):15927-15938. doi: 10.1074/jbc.M117.785253. Epub 2017 Aug 2.

PMID:
28768768
5.

A Missense Mutation in the Extracellular Domain of αENaC Causes Liddle Syndrome.

Salih M, Gautschi I, van Bemmelen MX, Di Benedetto M, Brooks AS, Lugtenberg D, Schild L, Hoorn EJ.

J Am Soc Nephrol. 2017 Nov;28(11):3291-3299. doi: 10.1681/ASN.2016111163. Epub 2017 Jul 14.

PMID:
28710092
6.

ASIC1A in neurons is critical for fear-related behaviors.

Taugher RJ, Lu Y, Fan R, Ghobbeh A, Kreple CJ, Faraci FM, Wemmie JA.

Genes Brain Behav. 2017 Nov;16(8):745-755. doi: 10.1111/gbb.12398. Epub 2017 Jul 21.

PMID:
28657172
7.

TNF Lectin-Like Domain Restores Epithelial Sodium Channel Function in Frameshift Mutants Associated with Pseudohypoaldosteronism Type 1B.

Willam A, Aufy M, Tzotzos S, El-Malazi D, Poser F, Wagner A, Unterköfler B, Gurmani D, Martan D, Iqbal SM, Fischer B, Fischer H, Pietschmann H, Czikora I, Lucas R, Lemmens-Gruber R, Shabbir W.

Front Immunol. 2017 May 29;8:601. doi: 10.3389/fimmu.2017.00601. eCollection 2017.

8.

Flexible Proteins at the Origin of Life.

Pohorille A, Wilson MA, Shannon G.

Life (Basel). 2017 Jun 5;7(2). pii: E23. doi: 10.3390/life7020023.

9.

A selectivity filter at the intracellular end of the acid-sensing ion channel pore.

Lynagh T, Flood E, Boiteux C, Wulf M, Komnatnyy VV, Colding JM, Allen TW, Pless SA.

Elife. 2017 May 12;6. pii: e24630. doi: 10.7554/eLife.24630.

10.

Identification of a cono-RFamide from the venom of Conus textile that targets ASIC3 and enhances muscle pain.

Reimers C, Lee CH, Kalbacher H, Tian Y, Hung CH, Schmidt A, Prokop L, Kauferstein S, Mebs D, Chen CC, Gründer S.

Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3507-E3515. doi: 10.1073/pnas.1616232114. Epub 2017 Apr 10.

11.

Proton and non-proton activation of ASIC channels.

Gautschi I, van Bemmelen MX, Schild L.

PLoS One. 2017 Apr 6;12(4):e0175293. doi: 10.1371/journal.pone.0175293. eCollection 2017.

12.

Conformational dynamics and role of the acidic pocket in ASIC pH-dependent gating.

Vullo S, Bonifacio G, Roy S, Johner N, Bernèche S, Kellenberger S.

Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):3768-3773. doi: 10.1073/pnas.1620560114. Epub 2017 Mar 20.

13.

Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a.

Chassagnon IR, McCarthy CA, Chin YK, Pineda SS, Keramidas A, Mobli M, Pham V, De Silva TM, Lynch JW, Widdop RE, Rash LD, King GF.

Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):3750-3755. doi: 10.1073/pnas.1614728114. Epub 2017 Mar 20.

14.

Restoration of Epithelial Sodium Channel Function by Synthetic Peptides in Pseudohypoaldosteronism Type 1B Mutants.

Willam A, Aufy M, Tzotzos S, Evanzin H, Chytracek S, Geppert S, Fischer B, Fischer H, Pietschmann H, Czikora I, Lucas R, Lemmens-Gruber R, Shabbir W.

Front Pharmacol. 2017 Feb 24;8:85. doi: 10.3389/fphar.2017.00085. eCollection 2017.

15.

Deactivation kinetics of acid-sensing ion channel 1a are strongly pH-sensitive.

MacLean DM, Jayaraman V.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2504-E2513. doi: 10.1073/pnas.1620508114. Epub 2017 Mar 6.

16.

The Drosophila Postsynaptic DEG/ENaC Channel ppk29 Contributes to Excitatory Neurotransmission.

Hill A, Zheng X, Li X, McKinney R, Dickman D, Ben-Shahar Y.

J Neurosci. 2017 Mar 22;37(12):3171-3180. doi: 10.1523/JNEUROSCI.3850-16.2017. Epub 2017 Feb 17.

17.

Bile acids potentiate proton-activated currents in Xenopus laevis oocytes expressing human acid-sensing ion channel (ASIC1a).

Ilyaskin AV, Diakov A, Korbmacher C, Haerteis S.

Physiol Rep. 2017 Feb;5(3). pii: e13132. doi: 10.14814/phy2.13132.

18.

ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion.

Li WG, Liu MG, Deng S, Liu YM, Shang L, Ding J, Hsu TT, Jiang Q, Li Y, Li F, Zhu MX, Xu TL.

Nat Commun. 2016 Dec 7;7:13770. doi: 10.1038/ncomms13770.

19.

Interactions between intersubunit transmembrane domains regulate the chaperone-dependent degradation of an oligomeric membrane protein.

Buck TM, Jordahl AS, Yates ME, Preston GM, Cook E, Kleyman TR, Brodsky JL.

Biochem J. 2017 Feb 1;474(3):357-376. doi: 10.1042/BCJ20160760. Epub 2016 Nov 30.

PMID:
27903760
20.

ASIC1a Deficient Mice Show Unaltered Neurodegeneration in the Subacute MPTP Model of Parkinson Disease.

Komnig D, Imgrund S, Reich A, Gründer S, Falkenburger BH.

PLoS One. 2016 Nov 7;11(11):e0165235. doi: 10.1371/journal.pone.0165235. eCollection 2016.

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