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Items: 1 to 20 of 24


Extracellular matrix stiffness and cell contractility control RNA localization to promote cell migration.

Wang T, Hamilla S, Cam M, Aranda-Espinoza H, Mili S.

Nat Commun. 2017 Oct 12;8(1):896. doi: 10.1038/s41467-017-00884-y.


IMPs: an RNA-binding protein family that provides a link between stem cell maintenance in normal development and cancer.

Degrauwe N, Suvà ML, Janiszewska M, Riggi N, Stamenkovic I.

Genes Dev. 2016 Nov 15;30(22):2459-2474. Review.


IMP1, an mRNA binding protein that reduces the metastatic potential of breast cancer in a mouse model.

Nwokafor CU, Sellers RS, Singer RH.

Oncotarget. 2016 Nov 8;7(45):72662-72671. doi: 10.18632/oncotarget.12083.


IMP1 suppresses breast tumor growth and metastasis through the regulation of its target mRNAs.

Wang G, Huang Z, Liu X, Huang W, Chen S, Zhou Y, Li D, Singer RH, Gu W.

Oncotarget. 2016 Mar 29;7(13):15690-702. doi: 10.18632/oncotarget.7464.


Loss of Stromal IMP1 Promotes a Tumorigenic Microenvironment in the Colon.

Hamilton KE, Chatterji P, Lundsmith ET, Andres SF, Giroux V, Hicks PD, Noubissi FK, Spiegelman VS, Rustgi AK.

Mol Cancer Res. 2015 Nov;13(11):1478-86. doi: 10.1158/1541-7786.MCR-15-0224. Epub 2015 Jul 20.


Quantifying Protein-mRNA Interactions in Single Live Cells.

Wu B, Buxbaum AR, Katz ZB, Yoon YJ, Singer RH.

Cell. 2015 Jul 2;162(1):211-20. doi: 10.1016/j.cell.2015.05.054.


Specific interaction of KIF11 with ZBP1 regulates the transport of β-actin mRNA and cell motility.

Song T, Zheng Y, Wang Y, Katz Z, Liu X, Chen S, Singer RH, Gu W.

J Cell Sci. 2015 Mar 1;128(5):1001-10. doi: 10.1242/jcs.161679. Epub 2015 Jan 14.


Control of cell migration through mRNA localization and local translation.

Liao G, Mingle L, Van De Water L, Liu G.

Wiley Interdiscip Rev RNA. 2015 Jan-Feb;6(1):1-15. doi: 10.1002/wrna.1265. Epub 2014 Sep 28. Review.


IMP1 promotes tumor growth, dissemination and a tumor-initiating cell phenotype in colorectal cancer cell xenografts.

Hamilton KE, Noubissi FK, Katti PS, Hahn CM, Davey SR, Lundsmith ET, Klein-Szanto AJ, Rhim AD, Spiegelman VS, Rustgi AK.

Carcinogenesis. 2013 Nov;34(11):2647-54. doi: 10.1093/carcin/bgt217. Epub 2013 Jun 12.


IGF2BP1 promotes mesenchymal cell properties and migration of tumor-derived cells by enhancing the expression of LEF1 and SNAI2 (SLUG).

Zirkel A, Lederer M, Stöhr N, Pazaitis N, Hüttelmaier S.

Nucleic Acids Res. 2013 Jul;41(13):6618-36. doi: 10.1093/nar/gkt410. Epub 2013 May 15.


Sounds of silence: synonymous nucleotides as a key to biological regulation and complexity.

Shabalina SA, Spiridonov NA, Kashina A.

Nucleic Acids Res. 2013 Feb 1;41(4):2073-94. doi: 10.1093/nar/gks1205. Epub 2013 Jan 4. Review.


Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?

Bell JL, Wächter K, Mühleck B, Pazaitis N, Köhn M, Lederer M, Hüttelmaier S.

Cell Mol Life Sci. 2013 Aug;70(15):2657-75. doi: 10.1007/s00018-012-1186-z. Epub 2012 Oct 16. Review.


IGF2BP1: a post-transcriptional "driver" of tumor cell migration.

Stöhr N, Hüttelmaier S.

Cell Adh Migr. 2012 Jul-Aug;6(4):312-8. doi: 10.4161/cam.20628. Epub 2012 Jul 1.


Principles and roles of mRNA localization in animal development.

Medioni C, Mowry K, Besse F.

Development. 2012 Sep;139(18):3263-76. doi: 10.1242/dev.078626. Review.


IGF2BP1 promotes cell migration by regulating MK5 and PTEN signaling.

Stöhr N, Köhn M, Lederer M, Glass M, Reinke C, Singer RH, Hüttelmaier S.

Genes Dev. 2012 Jan 15;26(2):176-89. doi: 10.1101/gad.177642.111.


Regulation of local expression of cell adhesion and motility-related mRNAs in breast cancer cells by IMP1/ZBP1.

Gu W, Katz Z, Wu B, Park HY, Li D, Lin S, Wells AL, Singer RH.

J Cell Sci. 2012 Jan 1;125(Pt 1):81-91. doi: 10.1242/jcs.086132. Epub 2012 Jan 20.


Role of Shwachman-Bodian-Diamond syndrome protein in translation machinery and cell chemotaxis: a comparative genomics approach.

Vasieva O.

Adv Appl Bioinform Chem. 2011;4:43-50. doi: 10.2147/AABC.S23510. Epub 2011 Sep 21.


Actin cytoskeleton in myofibroblast differentiation: ultrastructure defining form and driving function.

Sandbo N, Dulin N.

Transl Res. 2011 Oct;158(4):181-96. doi: 10.1016/j.trsl.2011.05.004. Epub 2011 Jun 22. Review.


Nucleocytoplasmic shuttling of Ssd1 defines the destiny of its bound mRNAs.

Kurischko C, Kuravi VK, Herbert CJ, Luca FC.

Mol Microbiol. 2011 Aug;81(3):831-49. doi: 10.1111/j.1365-2958.2011.07731.x. Epub 2011 Jul 18.


In vivo imaging in cancer.

Condeelis J, Weissleder R.

Cold Spring Harb Perspect Biol. 2010 Dec;2(12):a003848. doi: 10.1101/cshperspect.a003848. Epub 2010 Sep 22. Review.

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