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Items: 1 to 20 of 22

1.

The point mutation UCH-L1 C152A protects primary neurons against cyclopentenone prostaglandin-induced cytotoxicity: implications for post-ischemic neuronal injury.

Liu H, Li W, Rose ME, Hickey RW, Chen J, Uechi GT, Balasubramani M, Day BW, Patel KV, Graham SH.

Cell Death Dis. 2015 Nov 5;6:e1966. doi: 10.1038/cddis.2015.323.

2.

A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript.

Ramani B, Harris GM, Huang R, Seki T, Murphy GG, Costa Mdo C, Fischer S, Saunders TL, Xia G, McEachin RC, Paulson HL.

Hum Mol Genet. 2015 Mar 1;24(5):1211-24. doi: 10.1093/hmg/ddu532. Epub 2014 Oct 15.

3.

A human sleep homeostasis phenotype in mice expressing a primate-specific PER3 variable-number tandem-repeat coding-region polymorphism.

Hasan S, van der Veen DR, Winsky-Sommerer R, Hogben A, Laing EE, Koentgen F, Dijk DJ, Archer SN.

FASEB J. 2014 Jun;28(6):2441-54. doi: 10.1096/fj.13-240135. Epub 2014 Feb 27.

4.

Gene targeting in mice: a review.

Bouabe H, Okkenhaug K.

Methods Mol Biol. 2013;1064:315-36. doi: 10.1007/978-1-62703-601-6_23. Review.

5.

Combining sperm plug genotyping and coat color chimerism predicts germline transmission.

Lee AY, Evans K, Willis B, Lloyd KC.

Transgenic Res. 2013 Dec;22(6):1265-72. doi: 10.1007/s11248-013-9731-6. Epub 2013 Jul 17.

6.

Impaired synaptic clustering of postsynaptic density proteins and altered signal transmission in hippocampal neurons, and disrupted learning behavior in PDZ1 and PDZ2 ligand binding-deficient PSD-95 knockin mice.

Nagura H, Ishikawa Y, Kobayashi K, Takao K, Tanaka T, Nishikawa K, Tamura H, Shiosaka S, Suzuki H, Miyakawa T, Fujiyoshi Y, Doi T.

Mol Brain. 2012 Dec 26;5:43. doi: 10.1186/1756-6606-5-43.

7.

An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1.

Kenneth NS, Younger JM, Hughes ED, Marcotte D, Barker PA, Saunders TL, Duckett CS.

Biochem J. 2012 Apr 15;443(2):355-9. doi: 10.1042/BJ20120249.

8.

The streptozotocin-induced diabetic nude mouse model: differences between animals from different sources.

Graham ML, Janecek JL, Kittredge JA, Hering BJ, Schuurman HJ.

Comp Med. 2011 Aug;61(4):356-60.

9.

IAPs limit activation of RIP kinases by TNF receptor 1 during development.

Moulin M, Anderton H, Voss AK, Thomas T, Wong WW, Bankovacki A, Feltham R, Chau D, Cook WD, Silke J, Vaux DL.

EMBO J. 2012 Apr 4;31(7):1679-91. doi: 10.1038/emboj.2012.18. Epub 2012 Feb 10.

10.

SAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradation.

Tan M, Zhao Y, Kim SJ, Liu M, Jia L, Saunders TL, Zhu Y, Sun Y.

Dev Cell. 2011 Dec 13;21(6):1062-76. doi: 10.1016/j.devcel.2011.09.014. Epub 2011 Nov 23.

11.

A noncoding point mutation of Zeb1 causes multiple developmental malformations and obesity in Twirler mice.

Kurima K, Hertzano R, Gavrilova O, Monahan K, Shpargel KB, Nadaraja G, Kawashima Y, Lee KY, Ito T, Higashi Y, Eisenman DJ, Strome SE, Griffith AJ.

PLoS Genet. 2011 Sep;7(9):e1002307. doi: 10.1371/journal.pgen.1002307. Epub 2011 Sep 29.

12.

Evidence that Cd101 is an autoimmune diabetes gene in nonobese diabetic mice.

Rainbow DB, Moule C, Fraser HI, Clark J, Howlett SK, Burren O, Christensen M, Moody V, Steward CA, Mohammed JP, Fusakio ME, Masteller EL, Finger EB, Houchins JP, Naf D, Koentgen F, Ridgway WM, Todd JA, Bluestone JA, Peterson LB, Mattner J, Wicker LS.

J Immunol. 2011 Jul 1;187(1):325-36. doi: 10.4049/jimmunol.1003523. Epub 2011 May 25.

13.

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication.

Bozdagi O, Sakurai T, Papapetrou D, Wang X, Dickstein DL, Takahashi N, Kajiwara Y, Yang M, Katz AM, Scattoni ML, Harris MJ, Saxena R, Silverman JL, Crawley JN, Zhou Q, Hof PR, Buxbaum JD.

Mol Autism. 2010 Dec 17;1(1):15. doi: 10.1186/2040-2392-1-15.

14.

Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system.

Nishino J, Saunders TL, Sagane K, Morrison SJ.

J Neurosci. 2010 Nov 10;30(45):15228-40. doi: 10.1523/JNEUROSCI.2286-10.2010.

15.

Production of p53 gene knockout rats by homologous recombination in embryonic stem cells.

Tong C, Li P, Wu NL, Yan Y, Ying QL.

Nature. 2010 Sep 9;467(7312):211-3. doi: 10.1038/nature09368. Epub 2010 Aug 11.

16.

Disruption of Sag/Rbx2/Roc2 induces radiosensitization by increasing ROS levels and blocking NF-kappaB activation in mouse embryonic stem cells.

Tan M, Zhu Y, Kovacev J, Zhao Y, Pan ZQ, Spitz DR, Sun Y.

Free Radic Biol Med. 2010 Sep 15;49(6):976-83. doi: 10.1016/j.freeradbiomed.2010.05.030. Epub 2010 Jun 8.

17.

Efficient generation of germ line transmitting chimeras from C57BL/6N ES cells by aggregation with outbred host embryos.

Gertsenstein M, Nutter LM, Reid T, Pereira M, Stanford WL, Rossant J, Nagy A.

PLoS One. 2010 Jun 22;5(6):e11260. doi: 10.1371/journal.pone.0011260.

18.

Conditional Niemann-Pick C mice demonstrate cell autonomous Purkinje cell neurodegeneration.

Elrick MJ, Pacheco CD, Yu T, Dadgar N, Shakkottai VG, Ware C, Paulson HL, Lieberman AP.

Hum Mol Genet. 2010 Mar 1;19(5):837-47. doi: 10.1093/hmg/ddp552. Epub 2009 Dec 10.

19.

Agouti C57BL/6N embryonic stem cells for mouse genetic resources.

Pettitt SJ, Liang Q, Rairdan XY, Moran JL, Prosser HM, Beier DR, Lloyd KC, Bradley A, Skarnes WC.

Nat Methods. 2009 Jul;6(7):493-5. doi: 10.1038/nmeth.1342. Epub 2009 Jun 14.

20.

RBX1/ROC1 disruption results in early embryonic lethality due to proliferation failure, partially rescued by simultaneous loss of p27.

Tan M, Davis SW, Saunders TL, Zhu Y, Sun Y.

Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6203-8. doi: 10.1073/pnas.0812425106. Epub 2009 Mar 26.

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