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Items: 15


Recent advances in understanding Cushing disease: resistance to glucocorticoid negative feedback and somatic USP8 mutations.

Daniel E, Newell-Price J.

F1000Res. 2017 May 2;6:613. doi: 10.12688/f1000research.10968.1. eCollection 2017. Review.


The Gene of the Ubiquitin-Specific Protease 8 Is Frequently Mutated in Adenomas Causing Cushing's Disease.

Perez-Rivas LG, Theodoropoulou M, Ferraù F, Nusser C, Kawaguchi K, Stratakis CA, Faucz FR, Wildemberg LE, Assié G, Beschorner R, Dimopoulou C, Buchfelder M, Popovic V, Berr CM, Tóth M, Ardisasmita AI, Honegger J, Bertherat J, Gadelha MR, Beuschlein F, Stalla G, Komada M, Korbonits M, Reincke M.

J Clin Endocrinol Metab. 2015 Jul;100(7):E997-1004. doi: 10.1210/jc.2015-1453. Epub 2015 May 5.


Recurrent gain-of-function USP8 mutations in Cushing's disease.

Ma ZY, Song ZJ, Chen JH, Wang YF, Li SQ, Zhou LF, Mao Y, Li YM, Hu RG, Zhang ZY, Ye HY, Shen M, Shou XF, Li ZQ, Peng H, Wang QZ, Zhou DZ, Qin XL, Ji J, Zheng J, Chen H, Wang Y, Geng DY, Tang WJ, Fu CW, Shi ZF, Zhang YC, Ye Z, He WQ, Zhang QL, Tang QS, Xie R, Shen JW, Wen ZJ, Zhou J, Wang T, Huang S, Qiu HJ, Qiao ND, Zhang Y, Pan L, Bao WM, Liu YC, Huang CX, Shi YY, Zhao Y.

Cell Res. 2015 Mar;25(3):306-17. doi: 10.1038/cr.2015.20. Epub 2015 Feb 13.


Synaptic strength is bidirectionally controlled by opposing activity-dependent regulation of Nedd4-1 and USP8.

Scudder SL, Goo MS, Cartier AE, Molteni A, Schwarz LA, Wright R, Patrick GN.

J Neurosci. 2014 Dec 10;34(50):16637-49. doi: 10.1523/JNEUROSCI.2452-14.2014.


Proteomic analysis of 14-3-3 zeta binding proteins in the mouse hippocampus.

Heverin M, Brennan GP, Koehler CJ, Treumann A, Henshall DC.

Int J Physiol Pathophysiol Pharmacol. 2012;4(2):74-83. Epub 2012 Jun 23.


PTMs in conversation: activity and function of deubiquitinating enzymes regulated via post-translational modifications.

Kessler BM, Edelmann MJ.

Cell Biochem Biophys. 2011 Jun;60(1-2):21-38. doi: 10.1007/s12013-011-9176-6. Review.


The deubiquitinating enzyme USP8 promotes trafficking and degradation of the chemokine receptor 4 at the sorting endosome.

Berlin I, Higginbotham KM, Dise RS, Sierra MI, Nash PD.

J Biol Chem. 2010 Nov 26;285(48):37895-908. doi: 10.1074/jbc.M110.129411. Epub 2010 Sep 27.


Regulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8·STAM complex.

Berlin I, Schwartz H, Nash PD.

J Biol Chem. 2010 Nov 5;285(45):34909-21. doi: 10.1074/jbc.M109.016287. Epub 2010 Aug 24.


14-3-3epsilon contributes to tumour suppression in laryngeal carcinoma by affecting apoptosis and invasion.

Che XH, Chen H, Xu ZM, Shang C, Sun KL, Fu WN.

BMC Cancer. 2010 Jun 19;10:306. doi: 10.1186/1471-2407-10-306.


Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt.

Mukai A, Yamamoto-Hino M, Awano W, Watanabe W, Komada M, Goto S.

EMBO J. 2010 Jul 7;29(13):2114-25. doi: 10.1038/emboj.2010.100. Epub 2010 May 21.


Diacylglycerol kinase delta and protein kinase C(alpha) modulate epidermal growth factor receptor abundance and degradation through ubiquitin-specific protease 8.

Cai J, Crotty TM, Reichert E, Carraway KL 3rd, Stafforini DM, Topham MK.

J Biol Chem. 2010 Mar 5;285(10):6952-9. doi: 10.1074/jbc.M109.055731. Epub 2010 Jan 11.


Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes.

Reyes-Turcu FE, Ventii KH, Wilkinson KD.

Annu Rev Biochem. 2009;78:363-97. doi: 10.1146/annurev.biochem.78.082307.091526. Review.


Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1.

Wang T, Yin L, Cooper EM, Lai MY, Dickey S, Pickart CM, Fushman D, Wilkinson KD, Cohen RE, Wolberger C.

J Mol Biol. 2009 Mar 6;386(4):1011-23. doi: 10.1016/j.jmb.2008.12.085. Epub 2009 Jan 13.


Protein partners of deubiquitinating enzymes.

Ventii KH, Wilkinson KD.

Biochem J. 2008 Sep 1;414(2):161-75. doi: 10.1042/BJ20080798. Review.


Reverse the curse--the role of deubiquitination in cell cycle control.

Song L, Rape M.

Curr Opin Cell Biol. 2008 Apr;20(2):156-63. doi: 10.1016/ Epub 2008 Mar 17. Review.

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