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Letter to the Editor Re: Ogawa, Y. Cancers 2016, 8, 28.

Koch CJ.

Cancers (Basel). 2016 May 24;8(6). pii: E53. doi: 10.3390/cancers8060053.


ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis.

Dey S, Sayers CM, Verginadis II, Lehman SL, Cheng Y, Cerniglia GJ, Tuttle SW, Feldman MD, Zhang PJ, Fuchs SY, Diehl JA, Koumenis C.

J Clin Invest. 2015 Jul 1;125(7):2592-608. doi: 10.1172/JCI78031. Epub 2015 May 26.


Optimizing hypoxia detection and treatment strategies.

Koch CJ, Evans SM.

Semin Nucl Med. 2015 Mar;45(2):163-76. doi: 10.1053/j.semnuclmed.2014.10.004. Review.


A bioactive probe for glutathione-dependent antioxidant capacity in breast cancer patients: implications in measuring biological effects of arsenic compounds.

Li J, Zhang D, Jefferson PA, Ward KM, Ayene IS.

J Pharmacol Toxicol Methods. 2014 Jan-Feb;69(1):39-48. doi: 10.1016/j.vascn.2013.10.004. Epub 2013 Oct 20.


The Role of Bystander Effects in the Antitumor Activity of the Hypoxia-Activated Prodrug PR-104.

Foehrenbacher A, Patel K, Abbattista MR, Guise CP, Secomb TW, Wilson WR, Hicks KO.

Front Oncol. 2013 Oct 7;3:263. doi: 10.3389/fonc.2013.00263. eCollection 2013.


Role of SUMO-specific protease 2 in reprogramming cellular glucose metabolism.

Tang S, Huang G, Tong X, Xu L, Cai R, Li J, Zhou X, Song S, Huang C, Cheng J.

PLoS One. 2013 May 14;8(5):e63965. doi: 10.1371/journal.pone.0063965. Print 2013.


A bioactive probe of the oxidative pentose phosphate cycle: novel strategy to reverse radioresistance in glucose deprived human colon cancer cells.

Li J, Ward KM, Zhang D, Dayanandam E, Denittis AS, Prendergast GC, Ayene IS.

Toxicol In Vitro. 2013 Feb;27(1):367-77. doi: 10.1016/j.tiv.2012.08.012. Epub 2012 Aug 16.


Isotopically nonstationary 13C flux analysis of Myc-induced metabolic reprogramming in B-cells.

Murphy TA, Dang CV, Young JD.

Metab Eng. 2013 Jan;15:206-17. doi: 10.1016/j.ymben.2012.07.008. Epub 2012 Aug 8.


The biphasic redox sensing of SENP3 accounts for the HIF-1 transcriptional activity shift by oxidative stress.

Wang Y, Yang J, Yang K, Cang H, Huang XZ, Li H, Yi J.

Acta Pharmacol Sin. 2012 Jul;33(7):953-63. doi: 10.1038/aps.2012.40. Epub 2012 Jun 11.


Hydroxyethyl disulfide as an efficient metabolic assay for cell viability in vitro.

Li J, Zhang D, Ward KM, Prendergast GC, Ayene IS.

Toxicol In Vitro. 2012 Jun;26(4):603-12. doi: 10.1016/j.tiv.2012.01.007. Epub 2012 Jan 31.


CNS hypoxia is more pronounced in murine cerebral than noncerebral malaria and is reversed by erythropoietin.

Hempel C, Combes V, Hunt NH, Kurtzhals JA, Grau GE.

Am J Pathol. 2011 Oct;179(4):1939-50. doi: 10.1016/j.ajpath.2011.06.027. Epub 2011 Aug 18.


Induction of a longer term component of isoprene release in darkened aspen leaves: origin and regulation under different environmental conditions.

Rasulov B, Hüve K, Laisk A, Niinemets Ü.

Plant Physiol. 2011 Jun;156(2):816-31. doi: 10.1104/pp.111.176222. Epub 2011 Apr 18.


Hypoxia and senescence: the impact of oxygenation on tumor suppression.

Welford SM, Giaccia AJ.

Mol Cancer Res. 2011 May;9(5):538-44. doi: 10.1158/1541-7786.MCR-11-0065. Epub 2011 Mar 8. Review.


Stabilization of hypoxia-inducible factor-1alpha protein in hypoxia occurs independently of mitochondrial reactive oxygen species production.

Chua YL, Dufour E, Dassa EP, Rustin P, Jacobs HT, Taylor CT, Hagen T.

J Biol Chem. 2010 Oct 8;285(41):31277-84. doi: 10.1074/jbc.M110.158485. Epub 2010 Jul 30.


Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1alpha-induced metabolic reprograming.

Zhao F, Mancuso A, Bui TV, Tong X, Gruber JJ, Swider CR, Sanchez PV, Lum JJ, Sayed N, Melo JV, Perl AE, Carroll M, Tuttle SW, Thompson CB.

Oncogene. 2010 May 20;29(20):2962-72. doi: 10.1038/onc.2010.67. Epub 2010 Mar 15.


Cellular transformation by cigarette smoke extract involves alteration of glycolysis and mitochondrial function in esophageal epithelial cells.

Kim MS, Huang Y, Lee J, Zhong X, Jiang WW, Ratovitski EA, Sidransky D.

Int J Cancer. 2010 Jul 15;127(2):269-81. doi: 10.1002/ijc.25057.


pO(2)-dependent NO production determines OPPC activity in macrophages.

Robinson MA, Tuttle SW, Otto CM, Koch CJ.

Free Radic Biol Med. 2010 Jan 15;48(2):189-95. doi: 10.1016/j.freeradbiomed.2009.10.027. Epub 2009 Oct 12.


Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect.

Chen Y, Cairns R, Papandreou I, Koong A, Denko NC.

PLoS One. 2009 Sep 15;4(9):e7033. doi: 10.1371/journal.pone.0007033.

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