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Items: 18


Antiepileptic drugs in development pipeline: A recent update.

Kaur H, Kumar B, Medhi B.

eNeurologicalSci. 2016 Jun 17;4:42-51. doi: 10.1016/j.ensci.2016.06.003. eCollection 2016 Sep. Review.


Genetic and Molecular Regulation of Extrasynaptic GABA-A Receptors in the Brain: Therapeutic Insights for Epilepsy.

Chuang SH, Reddy DS.

J Pharmacol Exp Ther. 2018 Feb;364(2):180-197. doi: 10.1124/jpet.117.244673. Epub 2017 Nov 15.


Ganaxolone: A New Treatment for Neonatal Seizures.

Yawno T, Miller SL, Bennet L, Wong F, Hirst JJ, Fahey M, Walker DW.

Front Cell Neurosci. 2017 Aug 22;11:246. doi: 10.3389/fncel.2017.00246. eCollection 2017. Review.


A randomized double-blind, placebo-controlled trial of ganaxolone in children and adolescents with fragile X syndrome.

Ligsay A, Van Dijck A, Nguyen DV, Lozano R, Chen Y, Bickel ES, Hessl D, Schneider A, Angkustsiri K, Tassone F, Ceulemans B, Kooy RF, Hagerman RJ.

J Neurodev Disord. 2017 Aug 2;9(1):26. doi: 10.1186/s11689-017-9207-8.


Clinical Potential of Neurosteroids for CNS Disorders.

Reddy DS, Estes WA.

Trends Pharmacol Sci. 2016 Jul;37(7):543-561. doi: 10.1016/ Epub 2016 May 5. Review.


Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research.

Porcu P, Barron AM, Frye CA, Walf AA, Yang SY, He XY, Morrow AL, Panzica GC, Melcangi RC.

J Neuroendocrinol. 2016 Feb;28(2):12351. doi: 10.1111/jne.12351. Review.


Differential interactions engendered by benzodiazepine and neuroactive steroid combinations on schedule-controlled responding in rats.

Gunter BW, Platt DM, Rowlett JK.

Pharmacol Biochem Behav. 2015 Oct;137:53-9. doi: 10.1016/j.pbb.2015.08.003. Epub 2015 Aug 6.


Modulation of the GABAergic pathway for the treatment of fragile X syndrome.

Lozano R, Hare EB, Hagerman RJ.

Neuropsychiatr Dis Treat. 2014 Sep 16;10:1769-79. doi: 10.2147/NDT.S42919. eCollection 2014. Review.


Pregnenolone sulfate as a modulator of synaptic plasticity.

Smith CC, Gibbs TT, Farb DH.

Psychopharmacology (Berl). 2014 Sep;231(17):3537-56. doi: 10.1007/s00213-014-3643-x. Epub 2014 Jul 6. Review.


Allopregnanolone and neuroinflammation: a focus on multiple sclerosis.

Noorbakhsh F, Baker GB, Power C.

Front Cell Neurosci. 2014 Jun 3;8:134. doi: 10.3389/fncel.2014.00134. eCollection 2014. Review.


Modulation of Immunity and the Inflammatory Response: A New Target for Treating Drug-resistant Epilepsy.

Yu N, Liu H, Di Q.

Curr Neuropharmacol. 2013 Jan;11(1):114-27. doi: 10.2174/157015913804999540.


Role of anticonvulsant and antiepileptogenic neurosteroids in the pathophysiology and treatment of epilepsy.

Reddy DS.

Front Endocrinol (Lausanne). 2011 Oct 5;2:38. doi: 10.3389/fendo.2011.00038. eCollection 2011.


Neuroendocrine aspects of catamenial epilepsy.

Reddy DS.

Horm Behav. 2013 Feb;63(2):254-66. doi: 10.1016/j.yhbeh.2012.04.016. Epub 2012 May 2. Review.


Impaired neurosteroid synthesis in multiple sclerosis.

Noorbakhsh F, Ellestad KK, Maingat F, Warren KG, Han MH, Steinman L, Baker GB, Power C.

Brain. 2011 Sep;134(Pt 9):2703-21. doi: 10.1093/brain/awr200.


Neurosteroids: endogenous role in the human brain and therapeutic potentials.

Reddy DS.

Prog Brain Res. 2010;186:113-37. doi: 10.1016/B978-0-444-53630-3.00008-7. Review.


Hormonal aspects of epilepsy.

Pennell PB.

Neurol Clin. 2009 Nov;27(4):941-65. doi: 10.1016/j.ncl.2009.08.005. Review.


Treatment of Lennox-Gastaut syndrome: overview and recent findings.

van Rijckevorsel K.

Neuropsychiatr Dis Treat. 2008 Dec;4(6):1001-19.


Simultaneous quantification of GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in human and rat serum.

Porcu P, O'Buckley TK, Alward SE, Marx CE, Shampine LJ, Girdler SS, Morrow AL.

Steroids. 2009 Apr-May;74(4-5):463-73. doi: 10.1016/j.steroids.2008.12.015. Epub 2009 Jan 13.

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