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Uncoupling Exercise Bioenergetics From Systemic Metabolic Homeostasis by Conditional Inactivation of Baf60 in Skeletal Muscle.

Meng ZX, Tao W, Sun J, Wang Q, Mi L, Lin JD.

Diabetes. 2018 Jan;67(1):85-97. doi: 10.2337/db17-0367. Epub 2017 Nov 1.


SIRT1 Activation by Resveratrol Alleviates Cardiac Dysfunction via Mitochondrial Regulation in Diabetic Cardiomyopathy Mice.

Ma S, Feng J, Zhang R, Chen J, Han D, Li X, Yang B, Li X, Fan M, Li C, Tian Z, Wang Y, Cao F.

Oxid Med Cell Longev. 2017;2017:4602715. doi: 10.1155/2017/4602715. Epub 2017 Aug 13.


Effects of ageing on pro-arrhythmic ventricular phenotypes in incrementally paced murine Pgc-1β -/- hearts.

Ahmad S, Valli H, Edling CE, Grace AA, Jeevaratnam K, Huang CL.

Pflugers Arch. 2017 Dec;469(12):1579-1590. doi: 10.1007/s00424-017-2054-3. Epub 2017 Aug 18.


Ectopic expression of Cdk8 induces eccentric hypertrophy and heart failure.

Hall DD, Ponce JM, Chen B, Spitler KM, Alexia A, Oudit GY, Song LS, Grueter CE.

JCI Insight. 2017 Aug 3;2(15). pii: 92476. doi: 10.1172/jci.insight.92476. [Epub ahead of print]


Molecular Mechanisms Underlying Cardiac Adaptation to Exercise.

Vega RB, Konhilas JP, Kelly DP, Leinwand LA.

Cell Metab. 2017 May 2;25(5):1012-1026. doi: 10.1016/j.cmet.2017.04.025. Review.


Female rats with severe left ventricle volume overload exhibit more cardiac hypertrophy but fewer myocardial transcriptional changes than males.

Beaumont C, Walsh-Wilkinson É, Drolet MC, Roussel É, Arsenault M, Couet J.

Sci Rep. 2017 Apr 7;7(1):729. doi: 10.1038/s41598-017-00855-9.


Cardiac nuclear receptors: architects of mitochondrial structure and function.

Vega RB, Kelly DP.

J Clin Invest. 2017 Apr 3;127(4):1155-1164. doi: 10.1172/JCI88888. Epub 2017 Feb 13. Review.


Cardiac Med1 deletion promotes early lethality, cardiac remodeling, and transcriptional reprogramming.

Spitler KM, Ponce JM, Oudit GY, Hall DD, Grueter CE.

Am J Physiol Heart Circ Physiol. 2017 Apr 1;312(4):H768-H780. doi: 10.1152/ajpheart.00728.2016. Epub 2017 Feb 3.


PGC-1α dictates endothelial function through regulation of eNOS expression.

Craige SM, Kröller-Schön S, Li C, Kant S, Cai S, Chen K, Contractor MM, Pei Y, Schulz E, Keaney JF Jr.

Sci Rep. 2016 Dec 2;6:38210. doi: 10.1038/srep38210.


Peroxisome proliferator-activated receptor-γ coactivator 1 α1 induces a cardiac excitation-contraction coupling phenotype without metabolic remodelling.

Mutikainen M, Tuomainen T, Naumenko N, Huusko J, Smirin B, Laidinen S, Kokki K, Hynynen H, Ylä-Herttuala S, Heinäniemi M, Ruas JL, Tavi P.

J Physiol. 2016 Dec 1;594(23):7049-7071. doi: 10.1113/JP272847.


Increased expression of estrogen-related receptor β during adaptation of adult cardiomyocytes to sustained hypoxia.

Cunningham KF, Beeson GC, Beeson CC, McDermott PJ.

Am J Cardiovasc Dis. 2016 May 18;6(2):46-54. eCollection 2016.


ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer.

Park S, Chang CY, Safi R, Liu X, Baldi R, Jasper JS, Anderson GR, Liu T, Rathmell JC, Dewhirst MW, Wood KC, Locasale JW, McDonnell DP.

Cell Rep. 2016 Apr 12;15(2):323-35. doi: 10.1016/j.celrep.2016.03.026. Epub 2016 Mar 31.


High Salt Diet Affects Renal Sodium Excretion and ERRα Expression.

Wang D, Wang Y, Liu FQ, Yuan ZY, Mu JJ.

Int J Mol Sci. 2016 Apr 1;17(4):480. doi: 10.3390/ijms17040480.


Mitochondrial protein hyperacetylation in the failing heart.

Horton JL, Martin OJ, Lai L, Riley NM, Richards AL, Vega RB, Leone TC, Pagliarini DJ, Muoio DM, Bedi KC Jr, Margulies KB, Coon JJ, Kelly DP.

JCI Insight. 2016 Feb;2(1). pii: e84897. Epub 2016 Feb 25.


The Failing Heart Relies on Ketone Bodies as a Fuel.

Aubert G, Martin OJ, Horton JL, Lai L, Vega RB, Leone TC, Koves T, Gardell SJ, Krüger M, Hoppel CL, Lewandowski ED, Crawford PA, Muoio DM, Kelly DP.

Circulation. 2016 Feb 23;133(8):698-705. doi: 10.1161/CIRCULATIONAHA.115.017355. Epub 2016 Jan 27.


Mitochondrial biogenesis and dynamics in the developing and diseased heart.

Dorn GW 2nd, Vega RB, Kelly DP.

Genes Dev. 2015 Oct 1;29(19):1981-91. doi: 10.1101/gad.269894.115. Review.


Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis.

Liao X, Zhang R, Lu Y, Prosdocimo DA, Sangwung P, Zhang L, Zhou G, Anand P, Lai L, Leone TC, Fujioka H, Ye F, Rosca MG, Hoppel CL, Schulze PC, Abel ED, Stamler JS, Kelly DP, Jain MK.

J Clin Invest. 2015 Sep;125(9):3461-76. doi: 10.1172/JCI79964. Epub 2015 Aug 4.


Maintaining ancient organelles: mitochondrial biogenesis and maturation.

Vega RB, Horton JL, Kelly DP.

Circ Res. 2015 May 22;116(11):1820-34. doi: 10.1161/CIRCRESAHA.116.305420. Review.


Estrogen-related Receptor β Reduces the Subnuclear Mobility of Estrogen Receptor α and Suppresses Estrogen-dependent Cellular Function.

Tanida T, Matsuda KI, Yamada S, Hashimoto T, Kawata M.

J Biol Chem. 2015 May 8;290(19):12332-45. doi: 10.1074/jbc.M114.619098. Epub 2015 Mar 24.


Muscle as a "mediator" of systemic metabolism.

Baskin KK, Winders BR, Olson EN.

Cell Metab. 2015 Feb 3;21(2):237-48. doi: 10.1016/j.cmet.2014.12.021. Review.

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