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Items: 1 to 20 of 48


Plasmid transfection influences the readout of nonsense-mediated mRNA decay reporter assays in human cells.

Gerbracht JV, Boehm V, Gehring NH.

Sci Rep. 2017 Sep 6;7(1):10616. doi: 10.1038/s41598-017-10847-4.


Premature termination codon readthrough in human cells occurs in novel cytoplasmic foci and requires UPF proteins.

Jia J, Werkmeister E, Gonzalez-Hilarion S, Leroy C, Gruenert DC, Lafont F, Tulasne D, Lejeune F.

J Cell Sci. 2017 Sep 15;130(18):3009-3022. doi: 10.1242/jcs.198176. Epub 2017 Jul 25.


Multifaceted Regulation of Gene Expression by the Apoptosis- and Splicing-Associated Protein Complex and Its Components.

Deka B, Singh KK.

Int J Biol Sci. 2017 Apr 10;13(5):545-560. doi: 10.7150/ijbs.18649. eCollection 2017. Review.


Control of gene expression through the nonsense-mediated RNA decay pathway.

Nickless A, Bailis JM, You Z.

Cell Biosci. 2017 May 19;7:26. doi: 10.1186/s13578-017-0153-7. eCollection 2017. Review.


Nonsense Suppression as an Approach to Treat Lysosomal Storage Diseases.

Keeling KM.

Diseases. 2016 Dec;4(4). pii: 32. doi: 10.3390/diseases4040032. Epub 2016 Oct 19.


A GC-rich sequence feature in the 3' UTR directs UPF1-dependent mRNA decay in mammalian cells.

Imamachi N, Salam KA, Suzuki Y, Akimitsu N.

Genome Res. 2017 Mar;27(3):407-418. doi: 10.1101/gr.206060.116. Epub 2016 Dec 9.


Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6- and SMG7-mediated degradation pathways.

Colombo M, Karousis ED, Bourquin J, Bruggmann R, M├╝hlemann O.

RNA. 2017 Feb;23(2):189-201. doi: 10.1261/rna.059055.116. Epub 2016 Nov 18.


The Exon Junction Complex Controls the Efficient and Faithful Splicing of a Subset of Transcripts Involved in Mitotic Cell-Cycle Progression.

Fukumura K, Wakabayashi S, Kataoka N, Sakamoto H, Suzuki Y, Nakai K, Mayeda A, Inoue K.

Int J Mol Sci. 2016 Aug 2;17(8). pii: E1153. doi: 10.3390/ijms17081153.


Degradation of Gadd45 mRNA by nonsense-mediated decay is essential for viability.

Nelson JO, Moore KA, Chapin A, Hollien J, Metzstein MM.

Elife. 2016 Mar 8;5. pii: e12876. doi: 10.7554/eLife.12876.


Proteomic Analysis Reveals Branch-specific Regulation of the Unfolded Protein Response by Nonsense-mediated mRNA Decay.

Sieber J, Hauer C, Bhuvanagiri M, Leicht S, Krijgsveld J, Neu-Yilik G, Hentze MW, Kulozik AE.

Mol Cell Proteomics. 2016 May;15(5):1584-97. doi: 10.1074/mcp.M115.054056. Epub 2016 Feb 20.


Embryonic Stem Cells Exhibit mRNA Isoform Specific Translational Regulation.

Wong QW, Vaz C, Lee QY, Zhao TY, Luo R, Archer SK, Preiss T, Tanavde V, Vardy LA.

PLoS One. 2016 Jan 22;11(1):e0143235. doi: 10.1371/journal.pone.0143235. eCollection 2016.


Mechanism and regulation of the nonsense-mediated decay pathway.

Hug N, Longman D, Cáceres JF.

Nucleic Acids Res. 2016 Feb 29;44(4):1483-95. doi: 10.1093/nar/gkw010. Epub 2016 Jan 14. Review.


Attenuation of nonsense-mediated mRNA decay facilitates the response to chemotherapeutics.

Popp MW, Maquat LE.

Nat Commun. 2015 Mar 26;6:6632. doi: 10.1038/ncomms7632.


Identification of elements in human long 3' UTRs that inhibit nonsense-mediated decay.

Toma KG, Rebbapragada I, Durand S, Lykke-Andersen J.

RNA. 2015 May;21(5):887-97. doi: 10.1261/rna.048637.114. Epub 2015 Mar 24.


Caspases shutdown nonsense-mediated mRNA decay during apoptosis.

Jia J, Furlan A, Gonzalez-Hilarion S, Leroy C, Gruenert DC, Tulasne D, Lejeune F.

Cell Death Differ. 2015 Nov;22(11):1754-63. doi: 10.1038/cdd.2015.18. Epub 2015 Mar 6.


Nonsense-mediated decay in genetic disease: friend or foe?

Miller JN, Pearce DA.

Mutat Res Rev Mutat Res. 2014 Oct-Dec;762:52-64. doi: 10.1016/j.mrrev.2014.05.001. Epub 2014 May 28. Review.


A post-translational regulatory switch on UPF1 controls targeted mRNA degradation.

Kurosaki T, Li W, Hoque M, Popp MW, Ermolenko DN, Tian B, Maquat LE.

Genes Dev. 2014 Sep 1;28(17):1900-16. doi: 10.1101/gad.245506.114.


Therapeutics based on stop codon readthrough.

Keeling KM, Xue X, Gunn G, Bedwell DM.

Annu Rev Genomics Hum Genet. 2014;15:371-94. doi: 10.1146/annurev-genom-091212-153527. Epub 2014 Apr 18. Review.


In vivo determination of direct targets of the nonsense-mediated decay pathway in Drosophila.

Chapin A, Hu H, Rynearson SG, Hollien J, Yandell M, Metzstein MM.

G3 (Bethesda). 2014 Mar 20;4(3):485-96. doi: 10.1534/g3.113.009357.

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