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Items: 11


Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection.

Steinrueck M, Guet CC.

Elife. 2017 Jul 25;6. pii: e25100. doi: 10.7554/eLife.25100.


Engineering targeted chromosomal amplifications in human breast epithelial cells.

Springer S, Yi KH, Park J, Rajpurohit A, Price AJ, Lauring J.

Breast Cancer Res Treat. 2015 Jul;152(2):313-21. doi: 10.1007/s10549-015-3468-2. Epub 2015 Jun 23.


Genomic organization and evolution of double minutes/homogeneously staining regions with MYC amplification in human cancer.

L'Abbate A, Macchia G, D'Addabbo P, Lonoce A, Tolomeo D, Trombetta D, Kok K, Bartenhagen C, Whelan CW, Palumbo O, Severgnini M, Cifola I, Dugas M, Carella M, De Bellis G, Rocchi M, Carbone L, Storlazzi CT.

Nucleic Acids Res. 2014 Aug;42(14):9131-45. doi: 10.1093/nar/gku590. Epub 2014 Jul 17.


Regulatory mechanisms that prevent re-initiation of DNA replication can be locally modulated at origins by nearby sequence elements.

Richardson CD, Li JJ.

PLoS Genet. 2014 Jun 19;10(6):e1004358. doi: 10.1371/journal.pgen.1004358. eCollection 2014 Jun.


Cancer quasispecies and stem-like adaptive aneuploidy.

Napoletani D, Signore M, Struppa DC.

F1000Res. 2013 Dec 6;2:268. doi: 10.12688/f1000research.2-268.v1. eCollection 2013.


Amplification of c-MYC and MLL Genes as a Marker of Clonal Cell Progression in Patients with Myeloid Malignancy and Trisomy of Chromosomes 8 or 11.

Angelova S, Jordanova M, Spassov B, Shivarov V, Simeonova M, Christov I, Angelova P, Alexandrova K, Stoimenov A, Nikolova V, Dimova I, Ganeva P, Tzvetkov N, Hadjiev E, Toshkov S.

Balkan J Med Genet. 2011 Dec;14(2):17-24. doi: 10.2478/v10034-011-0043-y.


Characterization of genetic rearrangements in esophageal squamous carcinoma cell lines by a combination of M-FISH and array-CGH: further confirmation of some split genomic regions in primary tumors.

Hao JJ, Shi ZZ, Zhao ZX, Zhang Y, Gong T, Li CX, Zhan T, Cai Y, Dong JT, Fu SB, Zhan QM, Wang MR.

BMC Cancer. 2012 Aug 24;12:367. doi: 10.1186/1471-2407-12-367.


Gene amplification in human cells knocked down for RAD54.

Ruiz-Herrera A, Smirnova A, Khoriauli L, Nergadze SG, Mondello C, Giulotto E.

Genome Integr. 2011 Mar 18;2(1):5. doi: 10.1186/2041-9414-2-5.


Germline variation controls the architecture of somatic alterations in tumors.

Dworkin AM, Ridd K, Bautista D, Allain DC, Iwenofu OH, Roy R, Bastian BC, Toland AE.

PLoS Genet. 2010 Sep 23;6(9):e1001136. doi: 10.1371/journal.pgen.1001136.


Gene amplification as double minutes or homogeneously staining regions in solid tumors: origin and structure.

Storlazzi CT, Lonoce A, Guastadisegni MC, Trombetta D, D'Addabbo P, Daniele G, L'Abbate A, Macchia G, Surace C, Kok K, Ullmann R, Purgato S, Palumbo O, Carella M, Ambros PF, Rocchi M.

Genome Res. 2010 Sep;20(9):1198-206. doi: 10.1101/gr.106252.110. Epub 2010 Jul 14.


The DNA damage-binding protein XPC is a frequent target for inactivation in squamous cell carcinomas.

de Feraudy S, Ridd K, Richards LM, Kwok PY, Revet I, Oh D, Feeney L, Cleaver JE.

Am J Pathol. 2010 Aug;177(2):555-62. doi: 10.2353/ajpath.2010.090925. Epub 2010 Jul 8.

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