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Items: 1 to 20 of 79


Norbenzomorphan Scaffold: Chemical Tool for Modulating Sigma Receptor-Subtype Selectivity.

Sahn JJ, Hodges TR, Chan JZ, Martin SF.

ACS Med Chem Lett. 2017 Mar 21;8(4):455-460. doi: 10.1021/acsmedchemlett.7b00066. eCollection 2017 Apr 13.


Membrane Associated Progesterone Receptors: Promiscuous Proteins with Pleiotropic Functions - Focus on Interactions with Cytochromes P450.

Ryu CS, Klein K, Zanger UM.

Front Pharmacol. 2017 Mar 27;8:159. doi: 10.3389/fphar.2017.00159. eCollection 2017. Review.


PGRMC1 Is a Novel Potential Tumor Biomarker of Human Renal Cell Carcinoma Based on Quantitative Proteomic and Integrative Biological Assessments.

Zhang D, Xia X, Wang X, Zhang P, Lu W, Yu Y, Deng S, Yang H, Zhu H, Xu N, Liang S.

PLoS One. 2017 Jan 20;12(1):e0170453. doi: 10.1371/journal.pone.0170453. eCollection 2017.


Conditional Ablation of Progesterone Receptor Membrane Component 2 Causes Female Premature Reproductive Senescence.

Clark NC, Pru CA, Yee SP, Lydon JP, Peluso JJ, Pru JK.

Endocrinology. 2017 Mar 1;158(3):640-651. doi: 10.1210/en.2016-1701.


The Role of Progesterone and a Novel Progesterone Receptor, Progesterone Receptor Membrane Component 1, in the Inflammatory Response of Fetal Membranes to Ureaplasma parvum Infection.

Feng L, Ransom CE, Nazzal MK, Allen TK, Li YJ, Truong T, Potts LC, Seed PC, Murtha AP.

PLoS One. 2016 Dec 15;11(12):e0168102. doi: 10.1371/journal.pone.0168102. eCollection 2016.


Small molecule modulator of sigma 2 receptor is neuroprotective and reduces cognitive deficits and neuroinflammation in experimental models of Alzheimer's disease.

Yi B, Sahn JJ, Ardestani PM, Evans AK, Scott LL, Chan JZ, Iyer S, Crisp A, Zuniga G, Pierce JT, Martin SF, Shamloo M.

J Neurochem. 2017 Feb;140(4):561-575. doi: 10.1111/jnc.13917.


A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of Ferrochelatase.

Piel RB 3rd, Shiferaw MT, Vashisht AA, Marcero JR, Praissman JL, Phillips JD, Wohlschlegel JA, Medlock AE.

Biochemistry. 2016 Sep 20;55(37):5204-17. doi: 10.1021/acs.biochem.6b00756. Epub 2016 Sep 9.


Modulatory Effects of Sex Steroids Progesterone and Estradiol on Odorant Evoked Responses in Olfactory Receptor Neurons.

Kanageswaran N, Nagel M, Scholz P, Mohrhardt J, Gisselmann G, Hatt H.

PLoS One. 2016 Aug 5;11(8):e0159640. doi: 10.1371/journal.pone.0159640. eCollection 2016.


PGRMC1 regulation by phosphorylation: potential new insights in controlling biological activity

Cahill MA, Jazayeri JA, Kovacevic Z, Richardson DR.

Oncotarget. 2016 Aug 9;7(32):50822-50827. doi: 10.18632/oncotarget.10691.


Functional Zonation of the Adult Mammalian Adrenal Cortex.

Vinson GP.

Front Neurosci. 2016 Jun 15;10:238. doi: 10.3389/fnins.2016.00238. eCollection 2016. Review.


PGRMC1 and the faithful progression through mitosis and meiosis.

Luciano AM, Peluso JJ.

Cell Cycle. 2016 Sep;15(17):2239-40. doi: 10.1080/15384101.2016.1205415. Epub 2016 Jun 29. No abstract available.


Progestin-mediated activation of MAPK and AKT in nuclear progesterone receptor negative breast epithelial cells: The role of membrane progesterone receptors.

Salazar M, Lerma-Ortiz A, Hooks GM, Ashley AK, Ashley RL.

Gene. 2016 Oct 10;591(1):6-13. doi: 10.1016/j.gene.2016.06.044. Epub 2016 Jun 24.


Conditional Ablation of Progesterone Receptor Membrane Component 1 Results in Subfertility in the Female and Development of Endometrial Cysts.

McCallum ML, Pru CA, Niikura Y, Yee SP, Lydon JP, Peluso JJ, Pru JK.

Endocrinology. 2016 Sep;157(9):3309-19. doi: 10.1210/en.2016-1081. Epub 2016 Jun 16.


PGRMC1 participates in late events of bovine granulosa cells mitosis and oocyte meiosis.

Terzaghi L, Tessaro I, Raucci F, Merico V, Mazzini G, Garagna S, Zuccotti M, Franciosi F, Lodde V.

Cell Cycle. 2016 Aug 2;15(15):2019-32. doi: 10.1080/15384101.2016.1192731. Epub 2016 Jun 3.


Cloning and olfactory expression of progestin receptors in the Chinese black sleeper Bostrichthys sinensis.

Zhang YT, Liu DT, Zhu Y, Chen SX, Hong WS.

Gen Comp Endocrinol. 2016 May 1;230-231:87-102. doi: 10.1016/j.ygcen.2016.03.029. Epub 2016 Mar 24.


Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance.

Kabe Y, Nakane T, Koike I, Yamamoto T, Sugiura Y, Harada E, Sugase K, Shimamura T, Ohmura M, Muraoka K, Yamamoto A, Uchida T, Iwata S, Yamaguchi Y, Krayukhina E, Noda M, Handa H, Ishimori K, Uchiyama S, Kobayashi T, Suematsu M.

Nat Commun. 2016 Mar 18;7:11030. doi: 10.1038/ncomms11030.


Norbenzomorphan Framework as a Novel Scaffold for Generating Sigma 2 Receptor/PGRMC1 Subtype-Selective Ligands.

Sahn JJ, Hodges TR, Chan JZ, Martin SF.

ChemMedChem. 2016 Mar 17;11(6):556-61. doi: 10.1002/cmdc.201500551. Epub 2016 Feb 24.


Progesterone receptor membrane component 1 promotes survival of human breast cancer cells and the growth of xenograft tumors.

Clark NC, Friel AM, Pru CA, Zhang L, Shioda T, Rueda BR, Peluso JJ, Pru JK.

Cancer Biol Ther. 2016;17(3):262-71. doi: 10.1080/15384047.2016.1139240. Epub 2016 Jan 19.


Progesterone receptor membrane component-1 regulates hepcidin biosynthesis.

Li X, Rhee DK, Malhotra R, Mayeur C, Hurst LA, Ager E, Shelton G, Kramer Y, McCulloh D, Keefe D, Bloch KD, Bloch DB, Peterson RT.

J Clin Invest. 2016 Jan;126(1):389-401. doi: 10.1172/JCI83831. Epub 2015 Dec 14.

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