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Items: 1 to 20 of 151


A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity.

Xu X, Fan Z, Liang C, Li L, Wang L, Liang Y, Wu J, Chang S, Yan Z, Lv Z, Fu J, Liu Y, Jin S, Wang T, Hong T, Dong Y, Ding L, Cheng L, Liu R, Fu S, Jiao S, Ye Q.

Nat Commun. 2017 Jan 17;8:14059. doi: 10.1038/ncomms14059.


The Expression and Clinical Outcome of pCHK2-Thr68 and pCDC25C-Ser216 in Breast Cancer.

Jiang H, Wang B, Zhang F, Qian Y, Chuang CC, Ying M, Wang Y, Zuo L.

Int J Mol Sci. 2016 Oct 28;17(11). pii: E1803.


Basal Tumor Cell Isolation and Patient-Derived Xenograft Engraftment Identify High-Risk Clinical Bladder Cancers.

Skowron KB, Pitroda SP, Namm JP, Balogun O, Beckett MA, Zenner ML, Fayanju O, Huang X, Fernandez C, Zheng W, Qiao G, Chin R, Kron SJ, Khodarev NN, Posner MC, Steinberg GD, Weichselbaum RR.

Sci Rep. 2016 Oct 24;6:35854. doi: 10.1038/srep35854.


Protein Phosphatases Involved in Regulating Mitosis: Facts and Hypotheses.

Kim HS, Fernandes G, Lee CW.

Mol Cells. 2016 Sep;39(9):654-62. doi: 10.14348/molcells.2016.0214. Review.


Phosphorylation of CDC25A on SER283 in late S/G2 by CDK/cyclin complexes accelerates mitotic entry.

Mazzolini L, Broban A, Froment C, Burlet-Schiltz O, Besson A, Manenti S, Dozier C.

Cell Cycle. 2016 Oct 17;15(20):2742-52. doi: 10.1080/15384101.2016.1220455.


Human TRIB2 Oscillates during the Cell Cycle and Promotes Ubiquitination and Degradation of CDC25C.

Liang KL, Paredes R, Carmody R, Eyers PA, Meyer S, McCarthy TV, Keeshan K.

Int J Mol Sci. 2016 Aug 23;17(9). pii: E1378. doi: 10.3390/ijms17091378.


PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis.

Liang J, Cao R, Zhang Y, Xia Y, Zheng Y, Li X, Wang L, Yang W, Lu Z.

Nat Commun. 2016 Aug 3;7:12431. doi: 10.1038/ncomms12431.


A genome-scale CRISPR-Cas9 screening method for protein stability reveals novel regulators of Cdc25A.

Wu Y, Zhou L, Wang X, Lu J, Zhang R, Liang X, Wang L, Deng W, Zeng YX, Huang H, Kang T.

Cell Discov. 2016 May 24;2:16014. doi: 10.1038/celldisc.2016.14.


Identification of Phosphorylated Cyclin-Dependent Kinase 1 Associated with Colorectal Cancer Survival Using Label-Free Quantitative Analyses.

Lin PC, Yang YF, Tyan YC, Hsiao ES, Chu PC, Lee CT, Lee JC, Chen YM, Liao PC.

PLoS One. 2016 Jul 6;11(7):e0158844. doi: 10.1371/journal.pone.0158844.


A dual molecular analogue tuner for dissecting protein function in mammalian cells.

Brosh R, Hrynyk I, Shen J, Waghray A, Zheng N, Lemischka IR.

Nat Commun. 2016 May 27;7:11742. doi: 10.1038/ncomms11742.


Phosphatases and kinases regulating CDC25 activity in the cell cycle: clinical implications of CDC25 overexpression and potential treatment strategies.

Sur S, Agrawal DK.

Mol Cell Biochem. 2016 May;416(1-2):33-46. doi: 10.1007/s11010-016-2693-2. Review.


HTLV-1 Rex Tunes the Cellular Environment Favorable for Viral Replication.

Nakano K, Watanabe T.

Viruses. 2016 Feb 24;8(3):58. doi: 10.3390/v8030058. Review.


To senesce or not to senesce: how primary human fibroblasts decide their cell fate after DNA damage.

Kollarovic G, Studencka M, Ivanova L, Lauenstein C, Heinze K, Lapytsko A, Talemi SR, Figueiredo AS, Schaber J.

Aging (Albany NY). 2016 Jan;8(1):158-77.


Cellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor Radiosensitization.

Maier P, Hartmann L, Wenz F, Herskind C.

Int J Mol Sci. 2016 Jan 14;17(1). pii: E102. doi: 10.3390/ijms17010102. Review.


Anti-cancer Activity of Osmanthus matsumuranus Extract by Inducing G2/M Arrest and Apoptosis in Human Hepatocellular Carcinoma Hep G2 Cells.

Jin S, Park HJ, Oh YN, Kwon HJ, Kim JH, Choi YH, Kim BW.

J Cancer Prev. 2015 Dec;20(4):241-9. doi: 10.15430/JCP.2015.20.4.241.


Motif co-regulation and co-operativity are common mechanisms in transcriptional, post-transcriptional and post-translational regulation.

Van Roey K, Davey NE.

Cell Commun Signal. 2015 Dec 1;13:45. doi: 10.1186/s12964-015-0123-9. Review.


Therapeutic effect of TMZ-POH on human nasopharyngeal carcinoma depends on reactive oxygen species accumulation.

Xie L, Song X, Guo W, Wang X, Wei L, Li Y, Lv L, Wang W, Chen TC, Song X.

Oncotarget. 2016 Jan 12;7(2):1651-62. doi: 10.18632/oncotarget.6410.


A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase.

Sakurikar N, Thompson R, Montano R, Eastman A.

Oncotarget. 2016 Jan 12;7(2):1380-94. doi: 10.18632/oncotarget.6364.


Short linear motifs - ex nihilo evolution of protein regulation.

Davey NE, Cyert MS, Moses AM.

Cell Commun Signal. 2015 Nov 21;13:43. doi: 10.1186/s12964-015-0120-z. Review.


Reversal effects of Raloxifene on paclitaxel resistance in 2 MDR breast cancer cells.

Xu L, Lei J, Jiang D, Zhou L, Wang S, Fan W.

Cancer Biol Ther. 2015;16(12):1794-801. doi: 10.1080/15384047.2015.1095409.

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