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Items: 1 to 20 of 21


Flow signaling and atherosclerosis.

Le NT, Sandhu UG, Quintana-Quezada RA, Hoang NM, Fujiwara K, Abe JI.

Cell Mol Life Sci. 2017 May;74(10):1835-1858. doi: 10.1007/s00018-016-2442-4. Epub 2016 Dec 30. Review.


Zebrafish Model for Functional Screening of Flow-Responsive Genes.

Serbanovic-Canic J, de Luca A, Warboys C, Ferreira PF, Luong LA, Hsiao S, Gauci I, Mahmoud M, Feng S, Souilhol C, Bowden N, Ashton JP, Walczak H, Firmin D, Krams R, Mason JC, Haskard DO, Sherwin S, Ridger V, Chico TJ, Evans PC.

Arterioscler Thromb Vasc Biol. 2017 Jan;37(1):130-143. doi: 10.1161/ATVBAHA.116.308502. Epub 2016 Nov 10.


Disturbed Flow-Induced Endothelial Proatherogenic Signaling Via Regulating Post-Translational Modifications and Epigenetic Events.

Heo KS, Berk BC, Abe J.

Antioxid Redox Signal. 2016 Sep 1;25(7):435-50. doi: 10.1089/ars.2015.6556. Epub 2016 Apr 5.


Biomechanical factors in atherosclerosis: mechanisms and clinical implications.

Kwak BR, Bäck M, Bochaton-Piallat ML, Caligiuri G, Daemen MJ, Davies PF, Hoefer IE, Holvoet P, Jo H, Krams R, Lehoux S, Monaco C, Steffens S, Virmani R, Weber C, Wentzel JJ, Evans PC.

Eur Heart J. 2014 Nov 14;35(43):3013-20, 3020a-3020d. doi: 10.1093/eurheartj/ehu353. Epub 2014 Sep 17.


The beneficial effect of melatonin in brain endothelial cells against oxygen-glucose deprivation followed by reperfusion-induced injury.

Song J, Kang SM, Lee WT, Park KA, Lee KM, Lee JE.

Oxid Med Cell Longev. 2014;2014:639531. doi: 10.1155/2014/639531. Epub 2014 Jul 14.


Shear stress and atherosclerosis.

Heo KS, Fujiwara K, Abe J.

Mol Cells. 2014 Jun;37(6):435-40. doi: 10.14348/molcells.2014.0078. Epub 2014 Apr 30. Review.


Primary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide.

He Q, Wang G, Wakade S, Dasgupta S, Dinkins M, Kong JN, Spassieva SD, Bieberich E.

Mol Biol Cell. 2014 Jun;25(11):1715-29. doi: 10.1091/mbc.E13-12-0730. Epub 2014 Apr 2.


p62 binding to protein kinase C ζ regulates tumor necrosis factor α-induced apoptotic pathway in endothelial cells.

Kim GY, Nigro P, Fujiwara K, Abe J, Berk BC.

Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):2974-80. doi: 10.1161/ATVBAHA.112.300054. Epub 2012 Sep 27.


Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation.

Le NT, Corsetti JP, Dehoff-Sparks JL, Sparks CE, Fujiwara K, Abe J.

Int J Inflam. 2012;2012:678190. Epub 2012 Sep 6.


Laminar flow activation of ERK5 leads to cytoprotective effect via CHIP-mediated p53 ubiquitination in endothelial cells.

Lim JH, Woo CH.

Anat Cell Biol. 2011 Dec;44(4):265-73. doi: 10.5115/acb.2011.44.4.265. Epub 2011 Dec 30.


Disturbed-flow-mediated vascular reactive oxygen species induce endothelial dysfunction.

Heo KS, Fujiwara K, Abe J.

Circ J. 2011;75(12):2722-30. Epub 2011 Nov 10. Review.


The role of blood flow in determining the sites of atherosclerotic plaques.

Warboys CM, Amini N, de Luca A, Evans PC.

F1000 Med Rep. 2011;3:5. doi: 10.3410/M3-5. Epub 2011 Mar 1.


PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation.

Heo KS, Lee H, Nigro P, Thomas T, Le NT, Chang E, McClain C, Reinhart-King CA, King MR, Berk BC, Fujiwara K, Woo CH, Abe J.

J Cell Biol. 2011 May 30;193(5):867-84. doi: 10.1083/jcb.201010051.


Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives.

Chiu JJ, Chien S.

Physiol Rev. 2011 Jan;91(1):327-87. doi: 10.1152/physrev.00047.2009. Review.


Flow shear stress and atherosclerosis: a matter of site specificity.

Nigro P, Abe J, Berk BC.

Antioxid Redox Signal. 2011 Sep 1;15(5):1405-14. doi: 10.1089/ars.2010.3679. Epub 2011 Apr 8. Review.


TNF-α signals through PKCζ/NF-κB to alter the tight junction complex and increase retinal endothelial cell permeability.

Aveleira CA, Lin CM, Abcouwer SF, Ambrósio AF, Antonetti DA.

Diabetes. 2010 Nov;59(11):2872-82. doi: 10.2337/db09-1606. Epub 2010 Aug 6.


PKCzeta decreases eNOS protein stability via inhibitory phosphorylation of ERK5.

Nigro P, Abe J, Woo CH, Satoh K, McClain C, O'Dell MR, Lee H, Lim JH, Li JD, Heo KS, Fujiwara K, Berk BC.

Blood. 2010 Sep 16;116(11):1971-9. doi: 10.1182/blood-2010-02-269134. Epub 2010 Jun 10.


Protein kinase C isoforms: Multi-functional regulators of cell life and death.

Reyland ME.

Front Biosci (Landmark Ed). 2009 Jan 1;14:2386-99. Review.


GRP78 upregulation by atheroprone shear stress via p38-, alpha2beta1-dependent mechanism in endothelial cells.

Feaver RE, Hastings NE, Pryor A, Blackman BR.

Arterioscler Thromb Vasc Biol. 2008 Aug;28(8):1534-41. doi: 10.1161/ATVBAHA.108.167999. Epub 2008 Jun 12.


Fluid shear stress inhibits TNF-mediated JNK activation via MEK5-BMK1 in endothelial cells.

Li L, Tatake RJ, Natarajan K, Taba Y, Garin G, Tai C, Leung E, Surapisitchat J, Yoshizumi M, Yan C, Abe J, Berk BC.

Biochem Biophys Res Commun. 2008 May 23;370(1):159-63. doi: 10.1016/j.bbrc.2008.03.051. Epub 2008 Mar 19.

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