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Items: 1 to 20 of 180

1.

Aberrant Signaling Pathways in T-Cell Acute Lymphoblastic Leukemia.

Bongiovanni D, Saccomani V, Piovan E.

Int J Mol Sci. 2017 Sep 5;18(9). pii: E1904. doi: 10.3390/ijms18091904. Review.

2.

A pooled mutational analysis identifies ionizing radiation-associated mutational signatures conserved between mouse and human malignancies.

Davidson PR, Sherborne AL, Taylor B, Nakamura AO, Nakamura JL.

Sci Rep. 2017 Aug 9;7(1):7645. doi: 10.1038/s41598-017-07888-0.

3.

Dormant origins as a built-in safeguard in eukaryotic DNA replication against genome instability and disease development.

Shima N, Pederson KD.

DNA Repair (Amst). 2017 Aug;56:166-173. doi: 10.1016/j.dnarep.2017.06.019. Epub 2017 Jun 9. Review.

PMID:
28641940
4.

Modeling Genomic Instability and Selection Pressure in a Mouse Model of Melanoma.

Kwong LN, Zou L, Chagani S, Pedamallu CS, Liu M, Jiang S, Protopopov A, Zhang J, Getz G, Chin L.

Cell Rep. 2017 May 16;19(7):1304-1312. doi: 10.1016/j.celrep.2017.04.065.

5.

Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene.

Lefebure M, Tothill RW, Kruse E, Hawkins ED, Shortt J, Matthews GM, Gregory GP, Martin BP, Kelly MJ, Todorovski I, Doyle MA, Lupat R, Li J, Schroeder J, Wall M, Craig S, Poortinga G, Cameron D, Bywater M, Kats L, Gearhart MD, Bardwell VJ, Dickins RA, Hannan RD, Papenfuss AT, Johnstone RW.

Nat Commun. 2017 Mar 6;8:14581. doi: 10.1038/ncomms14581.

6.

IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting.

Takeda K, Nakayama M, Hayakawa Y, Kojima Y, Ikeda H, Imai N, Ogasawara K, Okumura K, Thomas DM, Smyth MJ.

Nat Commun. 2017 Feb 24;8:14607. doi: 10.1038/ncomms14607.

7.

Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures.

Graham NA, Minasyan A, Lomova A, Cass A, Balanis NG, Friedman M, Chan S, Zhao S, Delgado A, Go J, Beck L, Hurtz C, Ng C, Qiao R, Ten Hoeve J, Palaskas N, Wu H, Müschen M, Multani AS, Port E, Larson SM, Schultz N, Braas D, Christofk HR, Mellinghoff IK, Graeber TG.

Mol Syst Biol. 2017 Feb 15;13(2):914. doi: 10.15252/msb.20167159.

8.

Genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer.

Pan Q, Lou X, Zhang J, Zhu Y, Li F, Shan Q, Chen X, Xie Y, Su S, Wei H, Lin L, Wu L, Liu S.

Sci Rep. 2017 Dec;7(1):25. doi: 10.1038/s41598-017-00057-3. Epub 2017 Feb 1. Erratum in: Sci Rep. 2017 Jun 1;7(1):2784.

9.

Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival.

Kang YJ, Balter B, Csizmadia E, Haas B, Sharma H, Bronson R, Yan CT.

Nat Commun. 2017 Jan 17;8:14013. doi: 10.1038/ncomms14013. Erratum in: Nat Commun. 2017 Aug 14;8:15795.

10.

EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor.

Takada M, Zhuang M, Inuzuka H, Zhang J, Zurlo G, Zhang J, Zhang Q.

Oncotarget. 2017 Jan 24;8(4):6787-6795. doi: 10.18632/oncotarget.14290.

11.

Phylooncogenomics: Examining the cancer genome in the context of vertebrate evolution.

Zhang G, Vemulapalli TH, Yang JY.

Appl Transl Genom. 2013 Jun 29;2:48-54. eCollection 2013 Dec 1. Review.

12.
13.

Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma.

McFadden DG, Politi K, Bhutkar A, Chen FK, Song X, Pirun M, Santiago PM, Kim-Kiselak C, Platt JT, Lee E, Hodges E, Rosebrock AP, Bronson RT, Socci ND, Hannon GJ, Jacks T, Varmus H.

Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):E6409-E6417. Epub 2016 Oct 4.

14.

NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K-AKT and JAK-STAT3 pathways.

Yuzugullu H, Von T, Thorpe LM, Walker SR, Roberts TM, Frank DA, Zhao JJ.

Cell Discov. 2016 Sep 20;2:16030. doi: 10.1038/celldisc.2016.30. eCollection 2016.

15.

IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias.

Gusscott S, Jenkins CE, Lam SH, Giambra V, Pollak M, Weng AP.

PLoS One. 2016 Aug 17;11(8):e0161158. doi: 10.1371/journal.pone.0161158. eCollection 2016.

16.

PTEN regulates EG5 to control spindle architecture and chromosome congression during mitosis.

He J, Zhang Z, Ouyang M, Yang F, Hao H, Lamb KL, Yang J, Yin Y, Shen WH.

Nat Commun. 2016 Aug 5;7:12355. doi: 10.1038/ncomms12355.

17.

PTEN regulates PLK1 and controls chromosomal stability during cell division.

Zhang Z, Hou SQ, He J, Gu T, Yin Y, Shen WH.

Cell Cycle. 2016 Sep 16;15(18):2476-85. doi: 10.1080/15384101.2016.1203493. Epub 2016 Jul 11.

18.

GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer.

Martinelli P, Carrillo-de Santa Pau E, Cox T, Sainz B Jr, Dusetti N, Greenhalf W, Rinaldi L, Costello E, Ghaneh P, Malats N, Büchler M, Pajic M, Biankin AV, Iovanna J, Neoptolemos J, Real FX.

Gut. 2017 Sep;66(9):1665-1676. doi: 10.1136/gutjnl-2015-311256. Epub 2016 Jun 20.

19.

Distinct oncogenic Ras signals characterized by profound differences in flux through the RasGDP/RasGTP cycle.

Mues M, Roose JP.

Small GTPases. 2017 Jan 2;8(1):20-25. doi: 10.1080/21541248.2016.1187323. Epub 2016 May 9.

20.

Genome maintenance in the context of 4D chromatin condensation.

Yu S, Yang F, Shen WH.

Cell Mol Life Sci. 2016 Aug;73(16):3137-50. doi: 10.1007/s00018-016-2221-2. Epub 2016 Apr 20. Review.

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