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Eicosapentaenoic acid shows anti-inflammatory effect via GPR120 in 3T3-L1 adipocytes and attenuates adipose tissue inflammation in diet-induced obese mice.

Yamada H, Umemoto T, Kakei M, Momomura SI, Kawakami M, Ishikawa SE, Hara K.

Nutr Metab (Lond). 2017 May 8;14:33. doi: 10.1186/s12986-017-0188-0. eCollection 2017.


Macrophage function in obesity-induced inflammation and insulin resistance.

Lauterbach MA, Wunderlich FT.

Pflugers Arch. 2017 Apr;469(3-4):385-396. doi: 10.1007/s00424-017-1955-5. Epub 2017 Feb 23. Review.


Green Tea Polyphenol Epigallocatechin-3-gallate Suppresses Toll-like Receptor 4 Expression via Up-regulation of E3 Ubiquitin-protein Ligase RNF216.

Kumazoe M, Nakamura Y, Yamashita M, Suzuki T, Takamatsu K, Huang Y, Bae J, Yamashita S, Murata M, Yamada S, Shinoda Y, Yamaguchi W, Toyoda Y, Tachibana H.

J Biol Chem. 2017 Mar 10;292(10):4077-4088. doi: 10.1074/jbc.M116.755959. Epub 2017 Feb 1.


Keeping It All Going-Complement Meets Metabolism.

Kolev M, Kemper C.

Front Immunol. 2017 Jan 18;8:1. doi: 10.3389/fimmu.2017.00001. eCollection 2017. Review.


Saturated palmitic acid induces myocardial inflammatory injuries through direct binding to TLR4 accessory protein MD2.

Wang Y, Qian Y, Fang Q, Zhong P, Li W, Wang L, Fu W, Zhang Y, Xu Z, Li X, Liang G.

Nat Commun. 2017 Jan 3;8:13997. doi: 10.1038/ncomms13997.


Linoleic acid causes greater weight gain than saturated fat without hypothalamic inflammation in the male mouse.

Mamounis KJ, Yasrebi A, Roepke TA.

J Nutr Biochem. 2017 Feb;40:122-131. doi: 10.1016/j.jnutbio.2016.10.016. Epub 2016 Nov 4.


Niacin promotes revascularization and recovery of limb function in diet-induced obese mice with peripheral ischemia.

Pang DK, Nong Z, Sutherland BG, Sawyez CG, Robson DL, Toma J, Pickering JG, Borradaile NM.

Pharmacol Res Perspect. 2016 Apr 14;4(3):e00233. doi: 10.1002/prp2.233. eCollection 2016 Jun.


IRF3 promotes adipose inflammation and insulin resistance and represses browning.

Kumari M, Wang X, Lantier L, Lyubetskaya A, Eguchi J, Kang S, Tenen D, Roh HC, Kong X, Kazak L, Ahmad R, Rosen ED.

J Clin Invest. 2016 Aug 1;126(8):2839-54. doi: 10.1172/JCI86080. Epub 2016 Jul 11.


Postprandial Inflammatory Responses and Free Fatty Acids in Plasma of Adults Who Consumed a Moderately High-Fat Breakfast with and without Blueberry Powder in a Randomized Placebo-Controlled Trial.

Ono-Moore KD, Snodgrass RG, Huang S, Singh S, Freytag TL, Burnett DJ, Bonnel EL, Woodhouse LR, Zunino SJ, Peerson JM, Lee JY, Rutledge JC, Hwang DH.

J Nutr. 2016 Jul;146(7):1411-9. doi: 10.3945/jn.115.223909. Epub 2016 Jun 15.


Longitudinal, Diet-induced Weight Gain is Associated with Increased Blood Monocytes and Reduced TLR4 Expression.

Strohacker K, Simpson RJ, Carpenter KC, Breslin WL, McFarlin BK.

Int J Exerc Sci. 2010 Jul 15;3(3):134-142. eCollection 2010.


Insulin sensitizers prevent fine particulate matter-induced vascular insulin resistance and changes in endothelial progenitor cell homeostasis.

Haberzettl P, McCracken JP, Bhatnagar A, Conklin DJ.

Am J Physiol Heart Circ Physiol. 2016 Jun 1;310(11):H1423-38. doi: 10.1152/ajpheart.00369.2015. Epub 2016 Mar 25.


Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model.

Cabalén ME, Cabral MF, Sanmarco LM, Andrada MC, Onofrio LI, Ponce NE, Aoki MP, Gea S, Cano RC.

Oncotarget. 2016 Mar 22;7(12):13400-15. doi: 10.18632/oncotarget.7630.


Modulation of Toll-like receptor signaling in innate immunity by natural products.

Chen L, Yu J.

Int Immunopharmacol. 2016 Aug;37:65-70. doi: 10.1016/j.intimp.2016.02.005. Epub 2016 Feb 15. Review.


MicroRNA-181b Improves Glucose Homeostasis and Insulin Sensitivity by Regulating Endothelial Function in White Adipose Tissue.

Sun X, Lin J, Zhang Y, Kang S, Belkin N, Wara AK, Icli B, Hamburg NM, Li D, Feinberg MW.

Circ Res. 2016 Mar 4;118(5):810-21. doi: 10.1161/CIRCRESAHA.115.308166. Epub 2016 Jan 7.


Systems-Pharmacology Dissection of Traditional Chinese Medicine Compound Saffron Formula Reveals Multi-scale Treatment Strategy for Cardiovascular Diseases.

Liu J, Mu J, Zheng C, Chen X, Guo Z, Huang C, Fu Y, Tian G, Shang H, Wang Y.

Sci Rep. 2016 Jan 27;6:19809. doi: 10.1038/srep19809.


Toll-like receptor 4-induced endoplasmic reticulum stress contributes to impairment of vasodilator action of insulin.

Kim JA, Jang HJ, Hwang DH.

Am J Physiol Endocrinol Metab. 2015 Nov 1;309(9):E767-76. doi: 10.1152/ajpendo.00369.2015. Epub 2015 Sep 8.


Does the sympathetic nervous system contribute to the pathophysiology of metabolic syndrome?

Moreira MC, Pinto IS, Mourão AA, Fajemiroye JO, Colombari E, Reis ÂA, Freiria-Oliveira AH, Ferreira-Neto ML, Pedrino GR.

Front Physiol. 2015 Aug 25;6:234. doi: 10.3389/fphys.2015.00234. eCollection 2015. Review.


Nutritional modulation of gut microbiota - the impact on metabolic disease pathophysiology.

Ojeda P, Bobe A, Dolan K, Leone V, Martinez K.

J Nutr Biochem. 2016 Feb;28:191-200. doi: 10.1016/j.jnutbio.2015.08.013. Epub 2015 Aug 20. Review.

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