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Items: 1 to 20 of 85


Purging Exhausted Virus-Specific CD8 T Cell Phenotypes by Somatic Cell Reprogramming.

Chan J, Kim PY, Kranz E, Nagaoka Y, Lee Y, Wen J, Elsaesser HJ, Qin M, Brooks DG, Ringpis GE, Chen ISY, Kamata M.

AIDS Res Hum Retroviruses. 2017 Nov;33(S1):S59-S69. doi: 10.1089/aid.2017.0161.


Immune response of T cells during herpes simplex virus type 1 (HSV-1) infection.

Zhang J, Liu H, Wei B.

J Zhejiang Univ Sci B. 2017 Apr.;18(4):277-288. doi: 10.1631/jzus.B1600460. Review.


T cell exhaustion: from pathophysiological basics to tumor immunotherapy.

Catakovic K, Klieser E, Neureiter D, Geisberger R.

Cell Commun Signal. 2017 Jan 5;15(1):1. doi: 10.1186/s12964-016-0160-z. Review.


Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques.

Roberts ER, Carnathan DG, Li H, Shaw GM, Silvestri G, Betts MR.

PLoS Pathog. 2016 Dec 30;12(12):e1006135. doi: 10.1371/journal.ppat.1006135. eCollection 2016 Dec.


The induction of CD80 and apoptosis on B cells and CD40L in CD4+ T cells in response to seasonal influenza vaccination distinguishes responders versus non-responders in healthy controls and aviremic ART-treated HIV-infected individuals.

Powell AM, Luo Z, Martin L, Wan Z, Ma L, Liao G, Song Y, Li X, Michael Kilby J, Huang L, Jiang W.

Vaccine. 2017 Feb 1;35(5):831-841. doi: 10.1016/j.vaccine.2016.12.026. Epub 2016 Dec 22.


Subset- and Antigen-Specific Effects of Treg on CD8+ T Cell Responses in Chronic HIV Infection.

Nikolova M, Wiedemann A, Muhtarova M, Achkova D, Lacabaratz C, Lévy Y.

PLoS Pathog. 2016 Nov 9;12(11):e1005995. doi: 10.1371/journal.ppat.1005995. eCollection 2016 Nov.


Programmed death-1+ T cells inhibit effector T cells at the pathological site of miliary tuberculosis.

Singh A, Mohan A, Dey AB, Mitra DK.

Clin Exp Immunol. 2017 Feb;187(2):269-283. doi: 10.1111/cei.12871. Epub 2016 Nov 24.


Programed death-1/programed death-ligand 1 expression in lymph nodes of HIV infected patients: results of a pilot safety study in rhesus macaques using anti-programed death-ligand 1 (Avelumab).

Gill AL, Green SA, Abdullah S, Le Saout C, Pittaluga S, Chen H, Turnier R, Lifson J, Godin S, Qin J, Sneller MC, Cuillerot JM, Sabzevari H, Lane HC, Catalfamo M.

AIDS. 2016 Oct 23;30(16):2487-2493.


Exhaustion of Activated CD8 T Cells Predicts Disease Progression in Primary HIV-1 Infection.

Hoffmann M, Pantazis N, Martin GE, Hickling S, Hurst J, Meyerowitz J, Willberg CB, Robinson N, Brown H, Fisher M, Kinloch S, Babiker A, Weber J, Nwokolo N, Fox J, Fidler S, Phillips R, Frater J; SPARTAC and CHERUB Investigators.

PLoS Pathog. 2016 Jul 14;12(7):e1005661. doi: 10.1371/journal.ppat.1005661. eCollection 2016 Jul.


TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection.

Chew GM, Fujita T, Webb GM, Burwitz BJ, Wu HL, Reed JS, Hammond KB, Clayton KL, Ishii N, Abdel-Mohsen M, Liegler T, Mitchell BI, Hecht FM, Ostrowski M, Shikuma CM, Hansen SG, Maurer M, Korman AJ, Deeks SG, Sacha JB, Ndhlovu LC.

PLoS Pathog. 2016 Jan 7;12(1):e1005349. doi: 10.1371/journal.ppat.1005349. eCollection 2016 Jan.


PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing.

Akhmetzyanova I, Drabczyk M, Neff CP, Gibbert K, Dietze KK, Werner T, Liu J, Chen L, Lang KS, Palmer BE, Dittmer U, Zelinskyy G.

PLoS Pathog. 2015 Oct 20;11(10):e1005224. doi: 10.1371/journal.ppat.1005224. eCollection 2015 Oct. Erratum in: PLoS Pathog. 2015 Dec;11(12):e1005364.


HIV therapeutic vaccines: moving towards a functional cure.

Mylvaganam GH, Silvestri G, Amara RR.

Curr Opin Immunol. 2015 Aug;35:1-8. doi: 10.1016/j.coi.2015.05.001. Epub 2015 May 18. Review.


Programmed death-1 controls T cell survival by regulating oxidative metabolism.

Tkachev V, Goodell S, Opipari AW, Hao LY, Franchi L, Glick GD, Ferrara JL, Byersdorfer CA.

J Immunol. 2015 Jun 15;194(12):5789-800. doi: 10.4049/jimmunol.1402180. Epub 2015 May 13.


Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8+ T-Cell Population in Elite Controllers.

Pombo C, Wherry EJ, Gostick E, Price DA, Betts MR.

J Infect Dis. 2015 Nov 1;212(9):1376-86. doi: 10.1093/infdis/jiv226. Epub 2015 Apr 15.


Role of PD-1 co-inhibitory pathway in HIV infection and potential therapeutic options.

Velu V, Shetty RD, Larsson M, Shankar EM.

Retrovirology. 2015 Feb 8;12:14. doi: 10.1186/s12977-015-0144-x. Review.


T cell exhaustion during persistent viral infections.

Kahan SM, Wherry EJ, Zajac AJ.

Virology. 2015 May;479-480:180-93. doi: 10.1016/j.virol.2014.12.033. Epub 2015 Jan 22. Review.


Rosuvastatin reduces vascular inflammation and T-cell and monocyte activation in HIV-infected subjects on antiretroviral therapy.

Funderburg NT, Jiang Y, Debanne SM, Labbato D, Juchnowski S, Ferrari B, Clagett B, Robinson J, Lederman MM, McComsey GA.

J Acquir Immune Defic Syndr. 2015 Apr 1;68(4):396-404. doi: 10.1097/QAI.0000000000000478.


Expansion of dysfunctional Tim-3-expressing effector memory CD8+ T cells during simian immunodeficiency virus infection in rhesus macaques.

Fujita T, Burwitz BJ, Chew GM, Reed JS, Pathak R, Seger E, Clayton KL, Rini JM, Ostrowski MA, Ishii N, Kuroda MJ, Hansen SG, Sacha JB, Ndhlovu LC.

J Immunol. 2014 Dec 1;193(11):5576-83. doi: 10.4049/jimmunol.1400961. Epub 2014 Oct 27.


Diminished viral control during simian immunodeficiency virus infection is associated with aberrant PD-1hi CD4 T cell enrichment in the lymphoid follicles of the rectal mucosa.

Mylvaganam GH, Velu V, Hong JJ, Sadagopal S, Kwa S, Basu R, Lawson B, Villinger F, Amara RR.

J Immunol. 2014 Nov 1;193(9):4527-36. doi: 10.4049/jimmunol.1401222. Epub 2014 Sep 22.


Animal models for viral infection and cell exhaustion.

McGary CS, Silvestri G, Paiardini M.

Curr Opin HIV AIDS. 2014 Sep;9(5):492-9. doi: 10.1097/COH.0000000000000093. Review.

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