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Items: 1 to 20 of 21

1.

Physical evidence supporting a ribosomal shunting mechanism of translation initiation for BACE1 mRNA.

Koh DC, Edelman GM, Mauro VP.

Translation (Austin). 2013 Apr 1;1(1):e24400. doi: 10.4161/trla.24400.

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PKR downregulation prevents neurodegeneration and β-amyloid production in a thiamine-deficient model.

Mouton-Liger F, Rebillat AS, Gourmaud S, Paquet C, Leguen A, Dumurgier J, Bernadelli P, Taupin V, Pradier L, Rooney T, Hugon J.

Cell Death Dis. 2015 Jan 15;6:e1594. doi: 10.1038/cddis.2014.552.

4.

Two novel DNA motifs are essential for BACE1 gene transcription.

Xiang Y, Meng S, Wang J, Li S, Liu J, Li H, Li T, Song W, Zhou W.

Sci Rep. 2014 Oct 31;4:6864. doi: 10.1038/srep06864.

5.

Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease.

Sadleir KR, Eimer WA, Kaufman RJ, Osten P, Vassar R.

PLoS One. 2014 Jul 3;9(7):e101643. doi: 10.1371/journal.pone.0101643. Erratum in: PLoS One. 2014;9(10):e110914.

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Roles of eIF2α kinases in the pathogenesis of Alzheimer's disease.

Ohno M.

Front Mol Neurosci. 2014 Apr 16;7:22. doi: 10.3389/fnmol.2014.00022. Review.

9.

Gene expression regulation by upstream open reading frames and human disease.

Barbosa C, Peixeiro I, Romão L.

PLoS Genet. 2013;9(8):e1003529. doi: 10.1371/journal.pgen.1003529. Review.

10.

Functional expression of human α9* nicotinic acetylcholine receptors in X. laevis oocytes is dependent on the α9 subunit 5' UTR.

Filchakova O, McIntosh JM.

PLoS One. 2013 May 22;8(5):e64655. doi: 10.1371/journal.pone.0064655.

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12.

Depletion of GGA1 and GGA3 mediates postinjury elevation of BACE1.

Walker KR, Kang EL, Whalen MJ, Shen Y, Tesco G.

J Neurosci. 2012 Jul 25;32(30):10423-37. doi: 10.1523/JNEUROSCI.5491-11.2012.

13.

RNA binding protein/RNA element interactions and the control of translation.

Pichon X, Wilson LA, Stoneley M, Bastide A, King HA, Somers J, Willis AE.

Curr Protein Pept Sci. 2012 Jun;13(4):294-304. Review.

14.

The Membrane-Bound Aspartyl Protease BACE1: Molecular and Functional Properties in Alzheimer's Disease and Beyond.

Dislich B, Lichtenthaler SF.

Front Physiol. 2012 Feb 17;3:8. doi: 10.3389/fphys.2012.00008.

15.

Activation of PKR causes amyloid ß-peptide accumulation via de-repression of BACE1 expression.

Ill-Raga G, Palomer E, Wozniak MA, Ramos-Fernández E, Bosch-Morató M, Tajes M, Guix FX, Galán JJ, Clarimón J, Antúnez C, Real LM, Boada M, Itzhaki RF, Fandos C, Muñoz FJ.

PLoS One. 2011;6(6):e21456. doi: 10.1371/journal.pone.0021456.

16.

Expression of the anti-amyloidogenic secretase ADAM10 is suppressed by its 5'-untranslated region.

Lammich S, Buell D, Zilow S, Ludwig AK, Nuscher B, Lichtenthaler SF, Prinzen C, Fahrenholz F, Haass C.

J Biol Chem. 2010 May 21;285(21):15753-60. doi: 10.1074/jbc.M110.110742.

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18.

The complex regulation of HIC (Human I-mfa domain containing protein) expression.

Reiss-Sklan E, Levitzki A, Naveh-Many T.

PLoS One. 2009 Jul 7;4(7):e6152. doi: 10.1371/journal.pone.0006152.

19.

Transcriptional and post-transcriptional profile of human chromosome 21.

Nikolaev SI, Deutsch S, Genolet R, Borel C, Parand L, Ucla C, Schütz F, Duriaux Sail G, Dupré Y, Jaquier-Gubler P, Araud T, Conne B, Descombes P, Vassalli JD, Curran J, Antonarakis SE.

Genome Res. 2009 Aug;19(8):1471-9. doi: 10.1101/gr.089425.108.

20.

Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis.

O'Connor T, Sadleir KR, Maus E, Velliquette RA, Zhao J, Cole SL, Eimer WA, Hitt B, Bembinster LA, Lammich S, Lichtenthaler SF, Hébert SS, De Strooper B, Haass C, Bennett DA, Vassar R.

Neuron. 2008 Dec 26;60(6):988-1009. doi: 10.1016/j.neuron.2008.10.047.

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