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Items: 17


Idiosyncratic Drug-Induced Liver Injury (IDILI): Potential Mechanisms and Predictive Assays.

Roth AD, Lee MY.

Biomed Res Int. 2017;2017:9176937. doi: 10.1155/2017/9176937. Review.


Hepatic macrophages in homeostasis and liver diseases: from pathogenesis to novel therapeutic strategies.

Ju C, Tacke F.

Cell Mol Immunol. 2016 May;13(3):316-27. doi: 10.1038/cmi.2015.104.


Drug-induced hepatotoxicity: metabolic, genetic and immunological basis.

Njoku DB.

Int J Mol Sci. 2014 Apr 22;15(4):6990-7003. doi: 10.3390/ijms15046990. Review.


Eosinophils mediate the pathogenesis of halothane-induced liver injury in mice.

Proctor WR, Chakraborty M, Chea LS, Morrison JC, Berkson JD, Semple K, Bourdi M, Pohl LR.

Hepatology. 2013 May;57(5):2026-36. doi: 10.1002/hep.26196.


Classical and alternative activation of rat hepatic sinusoidal endothelial cells by inflammatory stimuli.

Liu Y, Gardner CR, Laskin JD, Laskin DL.

Exp Mol Pathol. 2013 Feb;94(1):160-7. doi: 10.1016/j.yexmp.2012.10.015.


Deficiency of interleukin-15 enhances susceptibility to acetaminophen-induced liver injury in mice.

Hou HS, Liao CL, Sytwu HK, Liao NS, Huang TY, Hsieh TY, Chu HC.

PLoS One. 2012;7(9):e44880. doi: 10.1371/journal.pone.0044880.


Endogenous interleukin-4 regulates glutathione synthesis following acetaminophen-induced liver injury in mice.

Ryan PM, Bourdi M, Korrapati MC, Proctor WR, Vasquez RA, Yee SB, Quinn TD, Chakraborty M, Pohl LR.

Chem Res Toxicol. 2012 Jan 13;25(1):83-93. doi: 10.1021/tx2003992.


Macrophages and tissue injury: agents of defense or destruction?

Laskin DL, Sunil VR, Gardner CR, Laskin JD.

Annu Rev Pharmacol Toxicol. 2011;51:267-88. doi: 10.1146/annurev.pharmtox.010909.105812. Review.


Pathologic role of stressed-induced glucocorticoids in drug-induced liver injury in mice.

Masson MJ, Collins LA, Carpenter LD, Graf ML, Ryan PM, Bourdi M, Pohl LR.

Biochem Biophys Res Commun. 2010 Jul 2;397(3):453-8. doi: 10.1016/j.bbrc.2010.05.126.


Mechanisms of acetaminophen-induced liver necrosis.

Hinson JA, Roberts DW, James LP.

Handb Exp Pharmacol. 2010;(196):369-405. doi: 10.1007/978-3-642-00663-0_12. Review.


Macrophages and inflammatory mediators in chemical toxicity: a battle of forces.

Laskin DL.

Chem Res Toxicol. 2009 Aug;22(8):1376-85. doi: 10.1021/tx900086v.


Acetaminophen protects brain endothelial cells against oxidative stress.

Tripathy D, Grammas P.

Microvasc Res. 2009 May;77(3):289-96. doi: 10.1016/j.mvr.2009.02.002.


Protective role of c-Jun N-terminal kinase 2 in acetaminophen-induced liver injury.

Bourdi M, Korrapati MC, Chakraborty M, Yee SB, Pohl LR.

Biochem Biophys Res Commun. 2008 Sep 12;374(1):6-10. doi: 10.1016/j.bbrc.2008.06.065.


Hepatic Mrp4 induction following acetaminophen exposure is dependent on Kupffer cell function.

Campion SN, Johnson R, Aleksunes LM, Goedken MJ, van Rooijen N, Scheffer GL, Cherrington NJ, Manautou JE.

Am J Physiol Gastrointest Liver Physiol. 2008 Aug;295(2):G294-304. doi: 10.1152/ajpgi.00541.2007.

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