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Items: 1 to 20 of 108

1.

SETDB2 Links Glucocorticoid to Lipid Metabolism through Insig2a Regulation.

Roqueta-Rivera M, Esquejo RM, Phelan PE, Sandor K, Daniel B, Foufelle F, Ding J, Li X, Khorasanizadeh S, Osborne TF.

Cell Metab. 2016 Sep 13;24(3):474-84. doi: 10.1016/j.cmet.2016.07.025. Epub 2016 Aug 25.

PMID:
27568546
2.

Phosphatidylcholine: Greasing the Cholesterol Transport Machinery.

Lagace TA.

Lipid Insights. 2016 Apr 4;8(Suppl 1):65-73. doi: 10.4137/LPI.S31746. eCollection 2015. Review.

3.

Current trends in oxysterol research.

Griffiths WJ, Abdel-Khalik J, Hearn T, Yutuc E, Morgan AH, Wang Y.

Biochem Soc Trans. 2016 Apr 15;44(2):652-8. doi: 10.1042/BST20150255. Review.

4.

Direct Demonstration That Loop1 of Scap Binds to Loop7: A CRUCIAL EVENT IN CHOLESTEROL HOMEOSTASIS.

Zhang Y, Lee KM, Kinch LN, Clark L, Grishin NV, Rosenbaum DM, Brown MS, Goldstein JL, Radhakrishnan A.

J Biol Chem. 2016 Jun 10;291(24):12888-96. doi: 10.1074/jbc.M116.729798. Epub 2016 Apr 11.

PMID:
27068746
5.

A novel intrinsically fluorescent probe for study of uptake and trafficking of 25-hydroxycholesterol.

Iaea DB, Gale SE, Bielska AA, Krishnan K, Fujiwara H, Jiang H, Maxfield FR, Schlesinger PH, Covey DF, Schaffer JE, Ory DS.

J Lipid Res. 2015 Dec;56(12):2408-19. doi: 10.1194/jlr.D064287. Epub 2015 Oct 24.

PMID:
26497473
6.

MicroRNA-720 promotes in vitro cell migration by targeting Rab35 expression in cervical cancer cells.

Tang Y, Lin Y, Li C, Hu X, Liu Y, He M, Luo J, Sun G, Wang T, Li W, Guo M.

Cell Biosci. 2015 Sep 25;5:56. doi: 10.1186/s13578-015-0047-5. eCollection 2015.

7.

PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels.

Ren R, Zhou X, He Y, Ke M, Wu J, Liu X, Yan C, Wu Y, Gong X, Lei X, Yan SF, Radhakrishnan A, Yan N.

Science. 2015 Jul 10;349(6244):187-91. doi: 10.1126/science.aab1091.

8.

Identification of Cholesterol 25-Hydroxylase as a Novel Host Restriction Factor and a Part of the Primary Innate Immune Responses against Hepatitis C Virus Infection.

Xiang Y, Tang JJ, Tao W, Cao X, Song BL, Zhong J.

J Virol. 2015 Jul;89(13):6805-16. doi: 10.1128/JVI.00587-15. Epub 2015 Apr 22.

9.

Switch-like responses of two cholesterol sensors do not require protein oligomerization in membranes.

Gay A, Rye D, Radhakrishnan A.

Biophys J. 2015 Mar 24;108(6):1459-69. doi: 10.1016/j.bpj.2015.02.008.

10.

Cholesterol metabolism and homeostasis in the brain.

Zhang J, Liu Q.

Protein Cell. 2015 Apr;6(4):254-64. doi: 10.1007/s13238-014-0131-3. Epub 2015 Feb 15. Review.

11.

The nuclear receptor FXR uncouples the actions of miR-33 from SREBP-2.

Tarling EJ, Ahn H, de Aguiar Vallim TQ.

Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):787-95. doi: 10.1161/ATVBAHA.114.304179. Epub 2015 Jan 15.

12.

Cholesterol and breast cancer pathophysiology.

Nelson ER, Chang CY, McDonnell DP.

Trends Endocrinol Metab. 2014 Dec;25(12):649-55. doi: 10.1016/j.tem.2014.10.001. Epub 2014 Nov 4. Review.

13.

The estrogen receptor as a mediator of the pathological actions of cholesterol in breast cancer.

McDonnell DP, Chang CY, Nelson ER.

Climacteric. 2014 Dec;17 Suppl 2:60-5. doi: 10.3109/13697137.2014.966949. Epub 2014 Oct 16.

14.

The influence of ligand-activated LXR on primary human trophoblasts.

Larkin JC, Sears SB, Sadovsky Y.

Placenta. 2014 Nov;35(11):919-24. doi: 10.1016/j.placenta.2014.09.002. Epub 2014 Sep 10.

15.

Cholesterol in brain disease: sometimes determinant and frequently implicated.

Martín MG, Pfrieger F, Dotti CG.

EMBO Rep. 2014 Oct;15(10):1036-52. doi: 10.15252/embr.201439225. Epub 2014 Sep 15. Review.

16.

Obesity, cholesterol metabolism, and breast cancer pathogenesis.

McDonnell DP, Park S, Goulet MT, Jasper J, Wardell SE, Chang CY, Norris JD, Guyton JR, Nelson ER.

Cancer Res. 2014 Sep 15;74(18):4976-82. doi: 10.1158/0008-5472.CAN-14-1756. Epub 2014 Jul 24.

17.

Oxidation of 7-dehydrocholesterol and desmosterol by human cytochrome P450 46A1.

Goyal S, Xiao Y, Porter NA, Xu L, Guengerich FP.

J Lipid Res. 2014 Sep;55(9):1933-43. doi: 10.1194/jlr.M051508. Epub 2014 Jul 13. Erratum in: J Lipid Res. 2015 Nov;56(11):2226.

18.

Whole exome sequencing of familial hypercholesterolaemia patients negative for LDLR/APOB/PCSK9 mutations.

Futema M, Plagnol V, Li K, Whittall RA, Neil HA, Seed M; Simon Broome Consortium, Bertolini S, Calandra S, Descamps OS, Graham CA, Hegele RA, Karpe F, Durst R, Leitersdorf E, Lench N, Nair DR, Soran H, Van Bockxmeer FM; UK10K Consortium, Humphries SE.

J Med Genet. 2014 Aug;51(8):537-44. doi: 10.1136/jmedgenet-2014-102405. Epub 2014 Jul 1.

19.

Oxysterols and their cellular effectors.

Olkkonen VM, Béaslas O, Nissilä E.

Biomolecules. 2012 Feb 15;2(1):76-103. doi: 10.3390/biom2010076.

20.

Absence of Nceh1 augments 25-hydroxycholesterol-induced ER stress and apoptosis in macrophages.

Sekiya M, Yamamuro D, Ohshiro T, Honda A, Takahashi M, Kumagai M, Sakai K, Nagashima S, Tomoda H, Igarashi M, Okazaki H, Yagyu H, Osuga J, Ishibashi S.

J Lipid Res. 2014 Oct;55(10):2082-92. doi: 10.1194/jlr.M050864. Epub 2014 Jun 2.

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