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Items: 1 to 20 of 281


ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway.

Zhao Y, Hu X, Liu Y, Dong S, Wen Z, He W, Zhang S, Huang Q, Shi M.

Mol Cancer. 2017 Apr 13;16(1):79. doi: 10.1186/s12943-017-0648-1. Review.


Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens.

Chen XH, Liu SR, Peng B, Li D, Cheng ZX, Zhu JX, Zhang S, Peng YM, Li H, Zhang TT, Peng XX.

Front Immunol. 2017 Mar 6;8:207. doi: 10.3389/fimmu.2017.00207. eCollection 2017.


Itraconazole exerts its anti-melanoma effect by suppressing Hedgehog, Wnt, and PI3K/mTOR signaling pathways.

Liang G, Liu M, Wang Q, Shen Y, Mei H, Li D, Liu W.

Oncotarget. 2017 Apr 25;8(17):28510-28525. doi: 10.18632/oncotarget.15324.


Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses.

Kroczynska B, Blyth GT, Rafidi RL, Majchrzak-Kita B, Xu L, Saleiro D, Kosciuczuk EM, Jemielity J, Su B, Altman JK, Eklund EA, Fish EN, Platanias LC.

J Biol Chem. 2017 Mar 17;292(11):4743-4752. doi: 10.1074/jbc.M116.757666. Epub 2017 Feb 7.


Antiproliferative Effects of Cynara cardunculus L. var. altilis (DC) Lipophilic Extracts.

Ramos PA, Guerra ÂR, Guerreiro O, Santos SA, Oliveira H, Freire CS, Silvestre AJ, Duarte MF.

Int J Mol Sci. 2016 Dec 29;18(1). pii: E63. doi: 10.3390/ijms18010063.


Inactivation of Regulatory-associated Protein of mTOR (Raptor)/Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling in Osteoclasts Increases Bone Mass by Inhibiting Osteoclast Differentiation in Mice.

Dai Q, Xie F, Han Y, Ma X, Zhou S, Jiang L, Zou W, Wang J.

J Biol Chem. 2017 Jan 6;292(1):196-204. doi: 10.1074/jbc.M116.764761. Epub 2016 Nov 22.


4-hydroxynonenal-mediated signaling and aging.

Zhang H, Forman HJ.

Free Radic Biol Med. 2016 Nov 20. pii: S0891-5849(16)31055-3. doi: 10.1016/j.freeradbiomed.2016.11.032. [Epub ahead of print] Review.


Probing the PI3K/Akt/mTor pathway using 31P-NMR spectroscopy: routes to glycogen synthase kinase 3.

Phyu SM, Tseng CC, Fleming IN, Smith TA.

Sci Rep. 2016 Nov 4;6:36544. doi: 10.1038/srep36544.


Regulation of mTORC1 by lysosomal calcium and calmodulin.

Li RJ, Xu J, Fu C, Zhang J, Zheng YG, Jia H, Liu JO.

Elife. 2016 Oct 27;5. pii: e19360. doi: 10.7554/eLife.19360.


HBV core promoter mutations and AKT upregulate S-phase kinase-associated protein 2 to promote postoperative hepatocellular carcinoma progression.

Chen L, Gu L, Gu Y, Wang H, Deng M, Stamataki Z, Oo YH, Huang Y.

Sci Rep. 2016 Oct 25;6:35917. doi: 10.1038/srep35917.


Lowered Expression of Tumor Suppressor Candidate MYO1C Stimulates Cell Proliferation, Suppresses Cell Adhesion and Activates AKT.

Visuttijai K, Pettersson J, Mehrbani Azar Y, van den Bout I, Örndal C, Marcickiewicz J, Nilsson S, Hörnquist M, Olsson B, Ejeskär K, Behboudi A.

PLoS One. 2016 Oct 7;11(10):e0164063. doi: 10.1371/journal.pone.0164063. eCollection 2016.


Astragaloside IV ameliorates renal injury in db/db mice.

Sun H, Wang W, Han P, Shao M, Song G, Du H, Yi T, Li S.

Sci Rep. 2016 Sep 2;6:32545. doi: 10.1038/srep32545.


Effects of dietary protein restriction on muscle fiber characteristics and mTORC1 pathway in the skeletal muscle of growing-finishing pigs.

Li Y, Li F, Wu L, Wei H, Liu Y, Li T, Tan B, Kong X, Yao K, Chen S, Wu F, Duan Y, Yin Y.

J Anim Sci Biotechnol. 2016 Aug 22;7(1):47. doi: 10.1186/s40104-016-0106-8. eCollection 2016.


Avoidance and Subversion of Eukaryotic Homeostatic Autophagy Mechanisms by Bacterial Pathogens.

Miller C, Celli J.

J Mol Biol. 2016 Aug 28;428(17):3387-98. doi: 10.1016/j.jmb.2016.07.007. Epub 2016 Jul 22. Review.


mTOR Regulates Gap Junction Alpha-1 Protein Trafficking in Sertoli Cells and Is Required for the Maintenance of Spermatogenesis in Mice.

Boyer A, Girard M, Thimmanahalli DS, Levasseur A, Céleste C, Paquet M, Duggavathi R, Boerboom D.

Biol Reprod. 2016 Jul;95(1):13. doi: 10.1095/biolreprod.115.138016. Epub 2016 Jun 8.


MicroRNA-214 Reduces Insulin-like Growth Factor-1 (IGF-1) Receptor Expression and Downstream mTORC1 Signaling in Renal Carcinoma Cells.

Das F, Dey N, Bera A, Kasinath BS, Ghosh-Choudhury N, Choudhury GG.

J Biol Chem. 2016 Jul 8;291(28):14662-76. doi: 10.1074/jbc.M115.694331. Epub 2016 May 13.


Evaluation of energy metabolism and calcium homeostasis in cells affected by Shwachman-Diamond syndrome.

Ravera S, Dufour C, Cesaro S, Bottega R, Faleschini M, Cuccarolo P, Corsolini F, Usai C, Columbaro M, Cipolli M, Savoia A, Degan P, Cappelli E.

Sci Rep. 2016 May 5;6:25441. doi: 10.1038/srep25441.


T cells and IL-17 in lupus nephritis.

Koga T, Ichinose K, Tsokos GC.

Clin Immunol. 2016 Apr 21. pii: S1521-6616(16)30069-9. doi: 10.1016/j.clim.2016.04.010. [Epub ahead of print]


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