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Items: 1 to 20 of 23


Transcriptional regulation of importin-α1 by JunD modulates subcellular localization of RNA-binding protein HuR in intestinal epithelial cells.

Xu Y, Chen J, Xiao L, Chung HK, Zhang Y, Robinson JC, Rao JN, Wang JY.

Am J Physiol Cell Physiol. 2016 Dec 1;311(6):C874-C883. doi: 10.1152/ajpcell.00209.2016. Epub 2016 Oct 12.


Posttranscriptional regulation of intestinal epithelial integrity by noncoding RNAs.

Wang JY, Xiao L, Wang JY.

Wiley Interdiscip Rev RNA. 2017 Mar;8(2). doi: 10.1002/wrna.1399. Epub 2016 Oct 4. Review.


Posttranscriptional regulation of 14-3-3ζ by RNA-binding protein HuR modulating intestinal epithelial restitution after wounding.

Hansraj NZ, Xiao L, Wu J, Chen G, Turner DJ, Wang JY, Rao JN.

Physiol Rep. 2016 Jul;4(13). pii: e12858. doi: 10.14814/phy2.12858.


Skin Carcinogenesis Studies Using Mouse Models with Altered Polyamines.

Nowotarski SL, Feith DJ, Shantz LM.

Cancer Growth Metastasis. 2015 Aug 9;8(Suppl 1):17-27. doi: 10.4137/CGM.S21219. eCollection 2015. Review.


Competition between RNA-binding proteins CELF1 and HuR modulates MYC translation and intestinal epithelium renewal.

Liu L, Ouyang M, Rao JN, Zou T, Xiao L, Chung HK, Wu J, Donahue JM, Gorospe M, Wang JY.

Mol Biol Cell. 2015 May 15;26(10):1797-810. doi: 10.1091/mbc.E14-11-1500. Epub 2015 Mar 25.


JunD enhances miR-29b levels transcriptionally and posttranscriptionally to inhibit proliferation of intestinal epithelial cells.

Zou T, Rao JN, Liu L, Xiao L, Chung HK, Li Y, Chen G, Gorospe M, Wang JY.

Am J Physiol Cell Physiol. 2015 May 15;308(10):C813-24. doi: 10.1152/ajpcell.00027.2015. Epub 2015 Mar 18.


Polyamines and Gut Mucosal Homeostasis.

Timmons J, Chang ET, Wang JY, Rao JN.

J Gastrointest Dig Syst. 2012 Feb 20;2(Suppl 7). pii: 001.


Endogenous polyamine function--the RNA perspective.

Lightfoot HL, Hall J.

Nucleic Acids Res. 2014 Oct;42(18):11275-90. doi: 10.1093/nar/gku837. Epub 2014 Sep 17. Review.


RNA-binding protein HuR promotes growth of small intestinal mucosa by activating the Wnt signaling pathway.

Liu L, Christodoulou-Vafeiadou E, Rao JN, Zou T, Xiao L, Chung HK, Yang H, Gorospe M, Kontoyiannis D, Wang JY.

Mol Biol Cell. 2014 Nov 1;25(21):3308-18. doi: 10.1091/mbc.E14-03-0853. Epub 2014 Aug 27.


RNA-binding proteins and microRNAs in gastrointestinal epithelial homeostasis and diseases.

Xiao L, Wang JY.

Curr Opin Pharmacol. 2014 Dec;19:46-53. doi: 10.1016/j.coph.2014.07.006. Epub 2014 Jul 24. Review.


Jnk2 deletion disrupts intestinal mucosal homeostasis and maturation by differentially modulating RNA-binding proteins HuR and CUGBP1.

Chung HK, Rao JN, Zou T, Liu L, Xiao L, Gu H, Turner DJ, Yang P, Wang JY.

Am J Physiol Cell Physiol. 2014 Jun 15;306(12):C1167-75. doi: 10.1152/ajpcell.00093.2014. Epub 2014 Apr 16.


Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis.

Luke CT, Casta A, Kim H, Christiano AM.

Exp Dermatol. 2013 Oct;22(10):644-9. doi: 10.1111/exd.12228.


miR-29b represses intestinal mucosal growth by inhibiting translation of cyclin-dependent kinase 2.

Xiao L, Rao JN, Zou T, Liu L, Cao S, Martindale JL, Su W, Chung HK, Gorospe M, Wang JY.

Mol Biol Cell. 2013 Oct;24(19):3038-46. doi: 10.1091/mbc.E13-05-0287. Epub 2013 Jul 31.


Polyamines inhibit the assembly of stress granules in normal intestinal epithelial cells regulating apoptosis.

Zou T, Rao JN, Liu L, Xiao L, Cui YH, Jiang Z, Ouyang M, Donahue JM, Wang JY.

Am J Physiol Cell Physiol. 2012 Jul 1;303(1):C102-11. doi: 10.1152/ajpcell.00009.2012. Epub 2012 May 2.


Spermine synthase overexpression in vivo does not increase susceptibility to DMBA/TPA skin carcinogenesis or Min-Apc intestinal tumorigenesis.

Welsh PA, Sass-Kuhn S, Prakashagowda C, McCloskey D, Feith D.

Cancer Biol Ther. 2012 Apr;13(6):358-68. doi: 10.4161/cbt.19241. Epub 2012 Apr 1.


Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function.

Yu TX, Wang PY, Rao JN, Zou T, Liu L, Xiao L, Gorospe M, Wang JY.

Nucleic Acids Res. 2011 Oct;39(19):8472-87. doi: 10.1093/nar/gkr567. Epub 2011 Jul 10.


Glutamine protects against apoptosis via downregulation of Sp3 in intestinal epithelial cells.

Ban K, Kozar RA.

Am J Physiol Gastrointest Liver Physiol. 2010 Dec;299(6):G1344-53. doi: 10.1152/ajpgi.00334.2010. Epub 2010 Sep 30.


Polyamines regulate the stability of JunD mRNA by modulating the competitive binding of its 3' untranslated region to HuR and AUF1.

Zou T, Rao JN, Liu L, Xiao L, Yu TX, Jiang P, Gorospe M, Wang JY.

Mol Cell Biol. 2010 Nov;30(21):5021-32. doi: 10.1128/MCB.00807-10. Epub 2010 Aug 30.


Induced ATF-2 represses CDK4 transcription through dimerization with JunD inhibiting intestinal epithelial cell growth after polyamine depletion.

Xiao L, Rao JN, Zou T, Liu L, Yu TX, Zhu XY, Donahue JM, Wang JY.

Am J Physiol Cell Physiol. 2010 May;298(5):C1226-34. doi: 10.1152/ajpcell.00021.2010. Epub 2010 Feb 24.


Post-transcriptional regulation of MEK-1 by polyamines through the RNA-binding protein HuR modulating intestinal epithelial apoptosis.

Wang PY, Rao JN, Zou T, Liu L, Xiao L, Yu TX, Turner DJ, Gorospe M, Wang JY.

Biochem J. 2010 Feb 24;426(3):293-306. doi: 10.1042/BJ20091459.

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