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Items: 1 to 20 of 27


Structure of mycobacterial 3'-to-5' RNA:DNA helicase Lhr bound to a ssDNA tracking strand highlights distinctive features of a novel family of bacterial helicases.

Ejaz A, Ordonez H, Jacewicz A, Ferrao R, Shuman S.

Nucleic Acids Res. 2018 Jan 9;46(1):442-455. doi: 10.1093/nar/gkx1163.


Genome Wide In silico Analysis of the Mismatch Repair Components of Plasmodium falciparum and Their Comparison with Human Host.

Tarique M, Ahmad M, Chauhan M, Tuteja R.

Front Microbiol. 2017 Feb 9;8:130. doi: 10.3389/fmicb.2017.00130. eCollection 2017.


Mycobacterium tuberculosis and Mycobacterium marinum non-homologous end-joining proteins can function together to join DNA ends in Escherichia coli.

Wright DG, Castore R, Shi R, Mallick A, Ennis DG, Harrison L.

Mutagenesis. 2017 Mar 1;32(2):245-256. doi: 10.1093/mutage/gew042.


C-terminal region of bacterial Ku controls DNA bridging, DNA threading and recruitment of DNA ligase D for double strand breaks repair.

McGovern S, Baconnais S, Roblin P, Nicolas P, Drevet P, Simonson H, Piétrement O, Charbonnier JB, Le Cam E, Noirot P, Lecointe F.

Nucleic Acids Res. 2016 Mar 9. pii: gkw149. [Epub ahead of print]


Comparative Genomics of Field Isolates of Mycobacterium bovis and M. caprae Provides Evidence for Possible Correlates with Bacterial Viability and Virulence.

de la Fuente J, Díez-Delgado I, Contreras M, Vicente J, Cabezas-Cruz A, Tobes R, Manrique M, López V, Romero B, Bezos J, Dominguez L, Sevilla IA, Garrido JM, Juste R, Madico G, Jones-López E, Gortazar C.

PLoS Negl Trop Dis. 2015 Nov 19;9(11):e0004232. doi: 10.1371/journal.pntd.0004232. eCollection 2015 Nov.


Mycobacterium smegmatis HelY Is an RNA-Activated ATPase/dATPase and 3'-to-5' Helicase That Unwinds 3'-Tailed RNA Duplexes and RNA:DNA Hybrids.

Uson ML, Ordonez H, Shuman S.

J Bacteriol. 2015 Oct;197(19):3057-65. doi: 10.1128/JB.00418-15. Epub 2015 Jul 13.


Regulated Expression Systems for Mycobacteria and Their Applications.

Schnappinger D, Ehrt S.

Microbiol Spectr. 2014;2(1). pii: 03.


Characterization of three mycobacterial DinB (DNA polymerase IV) paralogs highlights DinB2 as naturally adept at ribonucleotide incorporation.

Ordonez H, Uson ML, Shuman S.

Nucleic Acids Res. 2014;42(17):11056-70. doi: 10.1093/nar/gku752. Epub 2014 Sep 8.


Plasmodium falciparum UvrD activities are downregulated by DNA-interacting compounds and its dsRNA inhibits malaria parasite growth.

Tarique M, Tabassum F, Ahmad M, Tuteja R; Malaria Group.

BMC Biochem. 2014 Apr 3;15:9. doi: 10.1186/1471-2091-15-9.


Site-2 protease substrate specificity and coupling in trans by a PDZ-substrate adapter protein.

Schneider JS, Reddy SP, E HY, Evans HW, Glickman MS.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19543-8. doi: 10.1073/pnas.1305934110. Epub 2013 Nov 11.


The minimal Bacillus subtilis nonhomologous end joining repair machinery.

de Vega M.

PLoS One. 2013 May 17;8(5):e64232. doi: 10.1371/journal.pone.0064232. Print 2013.


Mycobacterium smegmatis Lhr Is a DNA-dependent ATPase and a 3'-to-5' DNA translocase and helicase that prefers to unwind 3'-tailed RNA:DNA hybrids.

Ordonez H, Shuman S.

J Biol Chem. 2013 May 17;288(20):14125-34. doi: 10.1074/jbc.M113.466854. Epub 2013 Apr 2.


A conserved helicase processivity factor is needed for conjugation and replication of an integrative and conjugative element.

Thomas J, Lee CA, Grossman AD.

PLoS Genet. 2013;9(1):e1003198. doi: 10.1371/journal.pgen.1003198. Epub 2013 Jan 10.


Mycobacterium smegmatis SftH exemplifies a distinctive clade of superfamily II DNA-dependent ATPases with 3' to 5' translocase and helicase activities.

Yakovleva L, Shuman S.

Nucleic Acids Res. 2012 Aug;40(15):7465-75. doi: 10.1093/nar/gks417. Epub 2012 May 27.


Enzymatic activities and DNA substrate specificity of Mycobacterium tuberculosis DNA helicase XPB.

Balasingham SV, Zegeye ED, Homberset H, Rossi ML, Laerdahl JK, Bohr VA, Tønjum T.

PLoS One. 2012;7(5):e36960. doi: 10.1371/journal.pone.0036960. Epub 2012 May 16.


Mycobacterium smegmatis RqlH defines a novel clade of bacterial RecQ-like DNA helicases with ATP-dependent 3'-5' translocase and duplex unwinding activities.

Ordonez H, Unciuleac M, Shuman S.

Nucleic Acids Res. 2012 May;40(10):4604-14. doi: 10.1093/nar/gks046. Epub 2012 Jan 28.


Catalytic and non-catalytic roles for the mono-ADP-ribosyltransferase Arr in the mycobacterial DNA damage response.

Stallings CL, Chu L, Li LX, Glickman MS.

PLoS One. 2011;6(7):e21807. doi: 10.1371/journal.pone.0021807. Epub 2011 Jul 18.


UvrD2 is essential in Mycobacterium tuberculosis, but its helicase activity is not required.

Williams A, Güthlein C, Beresford N, Böttger EC, Springer B, Davis EO.

J Bacteriol. 2011 Sep;193(17):4487-94. doi: 10.1128/JB.00302-11. Epub 2011 Jul 1.


A Sir2-like protein participates in mycobacterial NHEJ.

Li Z, Wen J, Lin Y, Wang S, Xue P, Zhang Z, Zhou Y, Wang X, Sui L, Bi LJ, Zhang XE.

PLoS One. 2011;6(5):e20045. doi: 10.1371/journal.pone.0020045. Epub 2011 May 26. Erratum in: PLoS One. 2011;6(7). doi:10.1371/annotation/a08b91f7-bf59-4384-8464-fca428ef15ef.

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