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Epidemiology and Outcomes of Pediatric Multiple Organ Dysfunction Syndrome.

Watson RS, Crow SS, Hartman ME, Lacroix J, Odetola FO.

Pediatr Crit Care Med. 2017 Mar;18(3_suppl Suppl 1):S4-S16. doi: 10.1097/PCC.0000000000001047.


Primary Outcome Measures in Pediatric Septic Shock Trials: A Systematic Review.

Menon K, McNally JD, Zimmerman JJ, Agus MS, O'Hearn K, Watson RS, Wong HR, Duffett M, Wypij D, Choong K.

Pediatr Crit Care Med. 2017 Mar;18(3):e146-e154. doi: 10.1097/PCC.0000000000001078.


Refractory septic shock in children: a European Society of Paediatric and Neonatal Intensive Care definition.

Morin L, Ray S, Wilson C, Remy S, Benissa MR, Jansen NJ, Javouhey E, Peters MJ, Kneyber M, De Luca D, Nadel S, Schlapbach LJ, Maclaren G, Tissieres P; ESPNIC Refractory Septic Shock Definition Taskforce the Infection Systemic Inflammation Sepsis section of ESPNIC .

Intensive Care Med. 2016 Dec;42(12):1948-1957. Epub 2016 Oct 5.


Dynamic Computational Model of Symptomatic Bacteremia to Inform Bacterial Separation Treatment Requirements.

Miller SE, Bell CS, McClain MS, Cover TL, Giorgio TD.

PLoS One. 2016 Sep 22;11(9):e0163167. doi: 10.1371/journal.pone.0163167. eCollection 2016.


Could Biomarkers Direct Therapy for the Septic Patient?

Sims CR, Nguyen TC, Mayeux PR.

J Pharmacol Exp Ther. 2016 May;357(2):228-39. doi: 10.1124/jpet.115.230797. Epub 2016 Feb 8. Review.


Research as a Standard of Care in the PICU.

Zimmerman JJ, Anand KJ, Meert KL, Willson DF, Newth CJ, Harrison R, Carcillo JA, Berger J, Jenkins TL, Nicholson C, Dean JM; Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.

Pediatr Crit Care Med. 2016 Jan;17(1):e13-21. doi: 10.1097/PCC.0000000000000562. Review.


It's About Time ….

Zimmerman JJ.

Pediatr Crit Care Med. 2015 Oct;16(8):793-5. doi: 10.1097/PCC.0000000000000532. No abstract available.


Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study.

Weiss SL, Fitzgerald JC, Maffei FA, Kane JM, Rodriguez-Nunez A, Hsing DD, Franzon D, Kee SY, Bush JL, Roy JA, Thomas NJ, Nadkarni VM; SPROUT Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators Network.

Crit Care. 2015 Sep 16;19:325. doi: 10.1186/s13054-015-1055-x.


Assessment of Fibrinolysis in Sepsis Patients with Urokinase Modified Thromboelastography.

Panigada M, Zacchetti L, L'Acqua C, Cressoni M, Anzoletti MB, Bader R, Protti A, Consonni D, D'Angelo A, Gattinoni L.

PLoS One. 2015 Aug 26;10(8):e0136463. doi: 10.1371/journal.pone.0136463. eCollection 2015.


Corticosteroids in Pediatric Shock: A Call to Arms.

Menon K, Wong HR.

Pediatr Crit Care Med. 2015 Oct;16(8):e313-7. doi: 10.1097/PCC.0000000000000513.


Laboratory evidence of disseminated intravascular coagulation is associated with a fatal outcome in children with cerebral malaria despite an absence of clinically evident thrombosis or bleeding.

Moxon CA, Chisala NV, Mzikamanda R, MacCormick I, Harding S, Downey C, Molyneux M, Seydel KB, Taylor TE, Heyderman RS, Toh CH.

J Thromb Haemost. 2015 Sep;13(9):1653-64. doi: 10.1111/jth.13060. Epub 2015 Aug 27. Erratum in: J Thromb Haemost. 2016 Feb;14(2):415.


Pediatric sepsis from start to finish.

Zimmerman JJ.

Pediatr Crit Care Med. 2015 Jun;16(5):479-80. doi: 10.1097/PCC.0000000000000389. No abstract available.


A recombinant fragment of von Willebrand factor reduces fibrin-rich microthrombi formation in mice with endotoxemia.

Nguyen TC, Gushiken F, Correa JI, Dong JF, Dasgupta SK, Thiagarajan P, Cruz MA.

Thromb Res. 2015 May;135(5):1025-30. doi: 10.1016/j.thromres.2015.02.033. Epub 2015 Mar 3.


Global epidemiology of pediatric severe sepsis: the sepsis prevalence, outcomes, and therapies study.

Weiss SL, Fitzgerald JC, Pappachan J, Wheeler D, Jaramillo-Bustamante JC, Salloo A, Singhi SC, Erickson S, Roy JA, Bush JL, Nadkarni VM, Thomas NJ; Sepsis Prevalence, Outcomes, and Therapies (SPROUT) Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.

Am J Respir Crit Care Med. 2015 May 15;191(10):1147-57. doi: 10.1164/rccm.201412-2323OC. Erratum in: Am J Respir Crit Care Med. 2016 Jan 15;193(2):223-4.


PAMPs and DAMPs as triggers for DIC.

Ito T.

J Intensive Care. 2014 Dec 31;2(1):67. doi: 10.1186/s40560-014-0065-0. eCollection 2014. Review.


Initial resuscitation and management of pediatric septic shock.

Martin K, Weiss SL.

Minerva Pediatr. 2015 Apr;67(2):141-58. Epub 2015 Jan 21. Review.


Consensus development for healthcare professionals.

Kea B, Sun BC.

Intern Emerg Med. 2015 Apr;10(3):373-83. doi: 10.1007/s11739-014-1156-6. Epub 2014 Nov 28.


Introduction to Pediatric Sepsis.

Wheeler DS.

Open Inflamm J. 2011 Oct 7;4(Suppl 1-M):1-3.


Mitochondrial dysfunction in peripheral blood mononuclear cells in pediatric septic shock.

Weiss SL, Selak MA, Tuluc F, Perales Villarroel J, Nadkarni VM, Deutschman CS, Becker LB.

Pediatr Crit Care Med. 2015 Jan;16(1):e4-e12. doi: 10.1097/PCC.0000000000000277.

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