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Opioid Antagonists and the A118G Polymorphism in the μ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype.

Ziauddeen H, Nestor LJ, Subramaniam N, Dodds C, Nathan PJ, Miller SR, Sarai BK, Maltby K, Fernando D, Warren L, Hosking LK, Waterworth D, Korzeniowska A, Win B, Richards DB, Vasist Johnson L, Fletcher PC, Bullmore ET.

Neuropsychopharmacology. 2016 Oct;41(11):2647-57. doi: 10.1038/npp.2016.60.


Pharmacogenetic approaches in the treatment of alcohol use disorders: addressing clinical utility and implementation thresholds.

Hendershot CS.

Addict Sci Clin Pract. 2014 Sep 13;9(1):20. doi: 10.1186/1940-0640-9-20. Review.


Associations of OPRM1 A118G and alcohol sensitivity with intravenous alcohol self-administration in young adults.

Hendershot CS, Claus ED, Ramchandani VA.

Addict Biol. 2016 Jan;21(1):125-35. doi: 10.1111/adb.12165.


Interactive effects of OPRM1 and DAT1 genetic variation on subjective responses to alcohol.

Ray LA, Bujarski S, Squeglia LM, Ashenhurst JR, Anton RF.

Alcohol Alcohol. 2014 May-Jun;49(3):261-70. doi: 10.1093/alcalc/agt183.


The value of extended pedigrees for next-generation analysis of complex disease in the rhesus macaque.

Vinson A, Prongay K, Ferguson B.

ILAR J. 2013;54(2):91-105. doi: 10.1093/ilar/ilt041. Review. Erratum in: ILAR J. 2014;55(2):371.


Large-scale polymorphism discovery in macaque G-protein coupled receptors.

Goswami DB, Ogawa LM, Ward JM, Miller GM, Vallender EJ.

BMC Genomics. 2013 Oct 11;14:703. doi: 10.1186/1471-2164-14-703.


Opioid pharmacogenetics of alcohol addiction.

Berrettini W.

Cold Spring Harb Perspect Med. 2013 Jul 1;3(7). pii: a012203. doi: 10.1101/cshperspect.a012203. Review.


Genetic and environmental determinants of stress responding.

Clarke TK, Nymberg C, Schumann G.

Alcohol Res. 2012;34(4):484-94. Review.


Subjective response to alcohol among alcohol-dependent individuals: effects of the μ-opioid receptor (OPRM1) gene and alcoholism severity.

Ray LA, Bujarski S, MacKillop J, Courtney KE, Monti PM, Miotto K.

Alcohol Clin Exp Res. 2013 Jan;37 Suppl 1:E116-24. doi: 10.1111/j.1530-0277.2012.01916.x.


CRHR1 genotypes, neural circuits and the diathesis for anxiety and depression.

Rogers J, Raveendran M, Fawcett GL, Fox AS, Shelton SE, Oler JA, Cheverud J, Muzny DM, Gibbs RA, Davidson RJ, Kalin NH.

Mol Psychiatry. 2013 Jun;18(6):700-7. doi: 10.1038/mp.2012.152.


The serotonin transporter gene is a substrate for age and stress dependent epigenetic regulation in rhesus macaque brain: potential roles in genetic selection and gene × environment interactions.

Lindell SG, Yuan Q, Zhou Z, Goldman D, Thompson RC, Lopez JF, Suomi SJ, Higley JD, Barr CS.

Dev Psychopathol. 2012 Nov;24(4):1391-400. doi: 10.1017/S0954579412000788. Erratum in: Dev Psychopathol. 2014 Nov;26(4 Pt 1):1181.


The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction.

Burkett JP, Young LJ.

Psychopharmacology (Berl). 2012 Nov;224(1):1-26. doi: 10.1007/s00213-012-2794-x. Review.


Naltrexone modification of drinking effects in a subacute treatment and bar-lab paradigm: influence of OPRM1 and dopamine transporter (SLC6A3) genes.

Anton RF, Voronin KK, Randall PK, Myrick H, Tiffany A.

Alcohol Clin Exp Res. 2012 Nov;36(11):2000-7. doi: 10.1111/j.1530-0277.2012.01807.x.


The genetics of the opioid system and specific drug addictions.

Levran O, Yuferov V, Kreek MJ.

Hum Genet. 2012 Jun;131(6):823-42. doi: 10.1007/s00439-012-1172-4. Review.


Medications development to treat alcohol dependence: a vision for the next decade.

Litten RZ, Egli M, Heilig M, Cui C, Fertig JB, Ryan ML, Falk DE, Moss H, Huebner R, Noronha A.

Addict Biol. 2012 May;17(3):513-27. doi: 10.1111/j.1369-1600.2012.00454.x. Review.


Pharmacogenetic approaches to the treatment of alcohol addiction.

Heilig M, Goldman D, Berrettini W, O'Brien CP.

Nat Rev Neurosci. 2011 Oct 20;12(11):670-84. doi: 10.1038/nrn3110. Review.


Functional polymorphism of the mu-opioid receptor gene (OPRM1) influences reinforcement learning in humans.

Lee MR, Gallen CL, Zhang X, Hodgkinson CA, Goldman D, Stein EA, Barr CS.

PLoS One. 2011;6(9):e24203. doi: 10.1371/journal.pone.0024203.


The role of the Asn40Asp polymorphism of the mu opioid receptor gene (OPRM1) on alcoholism etiology and treatment: a critical review.

Ray LA, Barr CS, Blendy JA, Oslin D, Goldman D, Anton RF.

Alcohol Clin Exp Res. 2012 Mar;36(3):385-94. doi: 10.1111/j.1530-0277.2011.01633.x. Review.


Mu-opioid receptor (OPRM1) variation, oxytocin levels and maternal attachment in free-ranging rhesus macaques Macaca mulatta.

Higham JP, Barr CS, Hoffman CL, Mandalaywala TM, Parker KJ, Maestripieri D.

Behav Neurosci. 2011 Apr;125(2):131-6. doi: 10.1037/a0022695.

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