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Items: 1 to 20 of 58


The IRF4 Gene Regulatory Module Functions as a Read-Write Integrator to Dynamically Coordinate T Helper Cell Fate.

Krishnamoorthy V, Kannanganat S, Maienschein-Cline M, Cook SL, Chen J, Bahroos N, Sievert E, Corse E, Chong A, Sciammas R.

Immunity. 2017 Sep 19;47(3):481-497.e7. doi: 10.1016/j.immuni.2017.09.001.


Normalized Synergy Predicts That CD8 Co-Receptor Contribution to T Cell Receptor (TCR) and pMHC Binding Decreases As TCR Affinity Increases in Human Viral-Specific T Cells.

Williams CM, Schonnesen AA, Zhang SQ, Ma KY, He C, Yamamoto T, Eckhardt SG, Klebanoff CA, Jiang N.

Front Immunol. 2017 Jul 28;8:894. doi: 10.3389/fimmu.2017.00894. eCollection 2017.


A systematic approach to cancer: evolution beyond selection.

Miller WB Jr, Torday JS.

Clin Transl Med. 2017 Dec;6(1):2. doi: 10.1186/s40169-016-0131-4. Epub 2017 Jan 3.


Phosphorylation of a Tyrosine Residue on Zap70 by Lck and Its Subsequent Binding via an SH2 Domain May Be a Key Gatekeeper of T Cell Receptor Signaling In Vivo.

Thill PA, Weiss A, Chakraborty AK.

Mol Cell Biol. 2016 Aug 26;36(18):2396-402. doi: 10.1128/MCB.00165-16. Print 2016 Sep 15.


Direct measurement of T cell receptor affinity and sequence from naïve antiviral T cells.

Zhang SQ, Parker P, Ma KY, He C, Shi Q, Cui Z, Williams CM, Wendel BS, Meriwether AI, Salazar MA, Jiang N.

Sci Transl Med. 2016 Jun 1;8(341):341ra77. doi: 10.1126/scitranslmed.aaf1278.


Inhibition of T cell receptor signaling by cholesterol sulfate, a naturally occurring derivative of membrane cholesterol.

Wang F, Beck-García K, Zorzin C, Schamel WW, Davis MM.

Nat Immunol. 2016 Jul;17(7):844-50. doi: 10.1038/ni.3462. Epub 2016 May 23.


Utilization of a photoactivatable antigen system to examine B-cell probing termination and the B-cell receptor sorting mechanisms during B-cell activation.

Wang J, Tang S, Wan Z, Gao Y, Cao Y, Yi J, Si Y, Zhang H, Liu L, Liu W.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E558-67. doi: 10.1073/pnas.1517612113. Epub 2016 Jan 13.


New approaches to understanding the immune response to vaccination and infection.

Furman D, Davis MM.

Vaccine. 2015 Sep 29;33(40):5271-81. doi: 10.1016/j.vaccine.2015.06.117. Epub 2015 Jul 29. Review.


Modulation of host immunity by tick saliva.

Kotál J, Langhansová H, Lieskovská J, Andersen JF, Francischetti IM, Chavakis T, Kopecký J, Pedra JH, Kotsyfakis M, Chmelař J.

J Proteomics. 2015 Oct 14;128:58-68. doi: 10.1016/j.jprot.2015.07.005. Epub 2015 Jul 17. Review.


Diversity index of mucosal resident T lymphocyte repertoire predicts clinical prognosis in gastric cancer.

Jia Q, Zhou J, Chen G, Shi Y, Yu H, Guan P, Lin R, Jiang N, Yu P, Li QJ, Wan Y.

Oncoimmunology. 2015 Jan 22;4(4):e1001230. eCollection 2015 Apr.


T Cell Receptor Engineering and Analysis Using the Yeast Display Platform.

Smith SN, Harris DT, Kranz DM.

Methods Mol Biol. 2015;1319:95-141. doi: 10.1007/978-1-4939-2748-7_6.


A biased competition theory of cytotoxic T lymphocyte interaction with tumor nodules.

Christophe C, Müller S, Rodrigues M, Petit AE, Cattiaux P, Dupré L, Gadat S, Valitutti S.

PLoS One. 2015 Mar 27;10(3):e0120053. doi: 10.1371/journal.pone.0120053. eCollection 2015.


Single-cell mass cytometry of TCR signaling: amplification of small initial differences results in low ERK activation in NOD mice.

Mingueneau M, Krishnaswamy S, Spitzer MH, Bendall SC, Stone EL, Hedrick SM, Pe'er D, Mathis D, Nolan GP, Benoist C.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16466-71. doi: 10.1073/pnas.1419337111. Epub 2014 Oct 31.


Insights into the initiation of TCR signaling.

Chakraborty AK, Weiss A.

Nat Immunol. 2014 Sep;15(9):798-807. doi: 10.1038/ni.2940. Review.


Lytic gene expression is frequent in HSV-1 latent infection and correlates with the engagement of a cell-intrinsic transcriptional response.

Ma JZ, Russell TA, Spelman T, Carbone FR, Tscharke DC.

PLoS Pathog. 2014 Jul 24;10(7):e1004237. doi: 10.1371/journal.ppat.1004237. eCollection 2014 Jul. Erratum in: PLoS Pathog. 2014 Aug;10(8):e1004361.


Engineered T cells for cancer therapy.

June CH, Maus MV, Plesa G, Johnson LA, Zhao Y, Levine BL, Grupp SA, Porter DL.

Cancer Immunol Immunother. 2014 Sep;63(9):969-75. doi: 10.1007/s00262-014-1568-1. Epub 2014 Jun 19. Review.


Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides.

Granados DP, Sriranganadane D, Daouda T, Zieger A, Laumont CM, Caron-Lizotte O, Boucher G, Hardy MP, Gendron P, Côté C, Lemieux S, Thibault P, Perreault C.

Nat Commun. 2014 Apr 9;5:3600. doi: 10.1038/ncomms4600.


Shaping the repertoire of tumor-infiltrating effector and regulatory T cells.

Savage PA, Leventhal DS, Malchow S.

Immunol Rev. 2014 May;259(1):245-58. doi: 10.1111/imr.12166. Review.


Adoptive immunotherapy for cancer or viruses.

Maus MV, Fraietta JA, Levine BL, Kalos M, Zhao Y, June CH.

Annu Rev Immunol. 2014;32:189-225. doi: 10.1146/annurev-immunol-032713-120136. Epub 2014 Jan 9. Review.


Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide-MHC.

Hoerter JA, Brzostek J, Artyomov MN, Abel SM, Casas J, Rybakin V, Ampudia J, Lotz C, Connolly JM, Chakraborty AK, Gould KG, Gascoigne NR.

J Exp Med. 2013 Aug 26;210(9):1807-21. doi: 10.1084/jem.20122528. Epub 2013 Aug 12.

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