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Items: 1 to 20 of 144


30 Years of NF-κB: A Blossoming of Relevance to Human Pathobiology.

Zhang Q, Lenardo MJ, Baltimore D.

Cell. 2017 Jan 12;168(1-2):37-57. doi: 10.1016/j.cell.2016.12.012. Review.


Late-phase synthesis of IκBα insulates the TLR4-activated canonical NF-κB pathway from noncanonical NF-κB signaling in macrophages.

Chatterjee B, Banoth B, Mukherjee T, Taye N, Vijayaragavan B, Chattopadhyay S, Gomes J, Basak S.

Sci Signal. 2016 Dec 6;9(457):ra120.


Non-canonical NFκB mutations reinforce pro-survival TNF response in multiple myeloma through an autoregulatory RelB:p50 NFκB pathway.

Roy P, Mukherjee T, Chatterjee B, Vijayaragavan B, Banoth B, Basak S.

Oncogene. 2017 Mar;36(10):1417-1429. doi: 10.1038/onc.2016.309.


TNFR2 expression by CD4 effector T cells is required to induce full-fledged experimental colitis.

Chen X, Nie Y, Xiao H, Bian Z, Scarzello AJ, Song NY, Anna TL, Yang D, Oppenheim JJ.

Sci Rep. 2016 Sep 7;6:32834. doi: 10.1038/srep32834.


Interplay of Murine Gammaherpesvirus 68 with NF-kappaB Signaling of the Host.

Cieniewicz B, Santana AL, Minkah N, Krug LT.

Front Microbiol. 2016 Aug 17;7:1202. doi: 10.3389/fmicb.2016.01202. Review.


Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein-protein interaction module.

Yim N, Ryu SW, Choi K, Lee KR, Lee S, Choi H, Kim J, Shaker MR, Sun W, Park JH, Kim D, Heo WD, Choi C.

Nat Commun. 2016 Jul 22;7:12277. doi: 10.1038/ncomms12277.


Innate immune memory and homeostasis may be conferred through crosstalk between the TLR3 and TLR7 pathways.

Liu B, Liu Q, Yang L, Palaniappan SK, Bahar I, Thiagarajan PS, Ding JL.

Sci Signal. 2016 Jul 12;9(436):ra70. doi: 10.1126/scisignal.aac9340.


Caspase-9b Interacts Directly with cIAP1 to Drive Agonist-Independent Activation of NF-κB and Lung Tumorigenesis.

Vu NT, Park MA, Shultz MD, Bulut GB, Ladd AC, Chalfant CE.

Cancer Res. 2016 May 15;76(10):2977-89. doi: 10.1158/0008-5472.CAN-15-2512.


The Ubiquitination of NF-κB Subunits in the Control of Transcription.

Collins PE, Mitxitorena I, Carmody RJ.

Cells. 2016 May 12;5(2). pii: E23. doi: 10.3390/cells5020023. Review.


TLR-mediated albuminuria needs TNFα-mediated cooperativity between TLRs present in hematopoietic tissues and CD80 present on non-hematopoietic tissues in mice.

Jain N, Khullar B, Oswal N, Banoth B, Joshi P, Ravindran B, Panda S, Basak S, George A, Rath S, Bal V, Sopory S.

Dis Model Mech. 2016 Jun 1;9(6):707-17. doi: 10.1242/dmm.023440.


Inhibition of PHLPP2/cyclin D1 protein translation contributes to the tumor suppressive effect of NFκB2 (p100).

Xu J, Wang Y, Hua X, Xu J, Tian Z, Jin H, Li J, Wu XR, Huang C.

Oncotarget. 2016 Jun 7;7(23):34112-30. doi: 10.18632/oncotarget.8746.


Roles of NF-κB in Cancer and Inflammatory Diseases and Their Therapeutic Approaches.

Park MH, Hong JT.

Cells. 2016 Mar 29;5(2). pii: E15. doi: 10.3390/cells5020015. Review.


Tumor-suppressor NFκB2 p100 interacts with ERK2 and stabilizes PTEN mRNA via inhibition of miR-494.

Wang Y, Xu J, Gao G, Li J, Huang H, Jin H, Zhu J, Che X, Huang C.

Oncogene. 2016 Aug 4;35(31):4080-90. doi: 10.1038/onc.2015.470.


Galactomannan Downregulates the Inflammation Responses in Human Macrophages via NFκB2/p100.

Toledano V, Hernández-Jiménez E, Cubillos-Zapata C, Flandez M, Álvarez E, Varela-Serrano A, Cantero R, Valles G, García-Rio F, López-Collazo E.

Mediators Inflamm. 2015;2015:942517. doi: 10.1155/2015/942517.


BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency.

Pache L, Dutra MS, Spivak AM, Marlett JM, Murry JP, Hwang Y, Maestre AM, Manganaro L, Vamos M, Teriete P, Martins LJ, König R, Simon V, Bosque A, Fernandez-Sesma A, Cosford ND, Bushman FD, Young JA, Planelles V, Chanda SK.

Cell Host Microbe. 2015 Sep 9;18(3):345-53. doi: 10.1016/j.chom.2015.08.009.


NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1.

Baig MS, Zaichick SV, Mao M, de Abreu AL, Bakhshi FR, Hart PC, Saqib U, Deng J, Chatterjee S, Block ML, Vogel SM, Malik AB, Consolaro ME, Christman JW, Minshall RD, Gantner BN, Bonini MG.

J Exp Med. 2015 Sep 21;212(10):1725-38. doi: 10.1084/jem.20140654.


A Regulated, Ubiquitin-Independent Degron in IκBα.

Fortmann KT, Lewis RD, Ngo KA, Fagerlund R, Hoffmann A.

J Mol Biol. 2015 Aug 28;427(17):2748-56. doi: 10.1016/j.jmb.2015.07.008.


Targeting signaling factors for degradation, an emerging mechanism for TRAF functions.

Yang XD, Sun SC.

Immunol Rev. 2015 Jul;266(1):56-71. doi: 10.1111/imr.12311. Review.


A dominant-negative F-box deleted mutant of E3 ubiquitin ligase, β-TrCP1/FWD1, markedly reduces myeloma cell growth and survival in mice.

Sharma R, Williams PJ, Gupta A, McCluskey B, Bhaskaran S, Muñoz S, Oyajobi BO.

Oncotarget. 2015 Aug 28;6(25):21589-602.


IκBβ enhances the generation of the low-affinity NFκB/RelA homodimer.

Tsui R, Kearns JD, Lynch C, Vu D, Ngo KA, Basak S, Ghosh G, Hoffmann A.

Nat Commun. 2015 May 7;6:7068. doi: 10.1038/ncomms8068.

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