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IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells.

Hsieh WC, Hsu TS, Chang YJ, Lai MZ.

Nat Commun. 2018 Jan 31;9(1):463. doi: 10.1038/s41467-018-02862-4.


Lymphocytes in Placental Tissues: Immune Regulation and Translational Possibilities for Immunotherapy.

Erkers T, Stikvoort A, Uhlin M.

Stem Cells Int. 2017;2017:5738371. doi: 10.1155/2017/5738371. Epub 2017 Nov 19. Review.


Pak2 is essential for the function of Foxp3+ regulatory T cells through maintaining a suppressive Treg phenotype.

O'Hagan KL, Miller SD, Phee H.

Sci Rep. 2017 Dec 6;7(1):17097. doi: 10.1038/s41598-017-17078-7.


Constitutive expression of NF-κB inducing kinase in regulatory T cells impairs suppressive function and promotes instability and pro-inflammatory cytokine production.

Polesso F, Sarker M, Anderson A, Parker DC, Murray SE.

Sci Rep. 2017 Nov 7;7(1):14779. doi: 10.1038/s41598-017-14965-x.


Blockage of FOXP3 transcription factor dimerization and FOXP3/AML1 interaction inhibits T regulatory cell activity: sequence optimization of a peptide inhibitor.

Lozano T, Gorraiz M, Lasarte-Cía A, Ruiz M, Rabal O, Oyarzabal J, Hervás-Stubbs S, Llopiz D, Sarobe P, Prieto J, Casares N, Lasarte JJ.

Oncotarget. 2017 May 13;8(42):71709-71724. doi: 10.18632/oncotarget.17845. eCollection 2017 Sep 22.


Newly Characterized Murine Undifferentiated Sarcoma Models Sensitive to Virotherapy with Oncolytic HSV-1 M002.

Ring EK, Li R, Moore BP, Nan L, Kelly VM, Han X, Beierle EA, Markert JM, Leavenworth JW, Gillespie GY, Friedman GK.

Mol Ther Oncolytics. 2017 Sep 13;7:27-36. doi: 10.1016/j.omto.2017.09.003. eCollection 2017 Dec 15.


Stability and function of regulatory T cells expressing the transcription factor T-bet.

Levine AG, Mendoza A, Hemmers S, Moltedo B, Niec RE, Schizas M, Hoyos BE, Putintseva EV, Chaudhry A, Dikiy S, Fujisawa S, Chudakov DM, Treuting PM, Rudensky AY.

Nature. 2017 Jun 15;546(7658):421-425. doi: 10.1038/nature22360. Epub 2017 Jun 7. Erratum in: Nature. 2017 Sep 20;:.


Transforming growth factor β: a master regulator of the gut microbiota and immune cell interactions.

Bauché D, Marie JC.

Clin Transl Immunology. 2017 Apr 7;6(4):e136. doi: 10.1038/cti.2017.9. eCollection 2017 Apr. Review.


Overexpression of fibrinogen-like protein 2 protects against T cell-induced colitis.

Bartczak A, Zhang J, Adeyi O, Amir A, Grant D, Gorczynski R, Selzner N, Chruscinski A, Levy GA.

World J Gastroenterol. 2017 Apr 21;23(15):2673-2684. doi: 10.3748/wjg.v23.i15.2673.


Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non-Small Cell Lung Cancer.

Adeegbe DO, Liu Y, Lizotte PH, Kamihara Y, Aref AR, Almonte C, Dries R, Li Y, Liu S, Wang X, Warner-Hatten T, Castrillon J, Yuan GC, Poudel-Neupane N, Zhang H, Guerriero JL, Han S, Awad MM, Barbie DA, Ritz J, Jones SS, Hammerman PS, Bradner J, Quayle SN, Wong KK.

Cancer Discov. 2017 Aug;7(8):852-867. doi: 10.1158/2159-8290.CD-16-1020. Epub 2017 Apr 13.


Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity.

Zemmour D, Pratama A, Loughhead SM, Mathis D, Benoist C.

Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3472-E3480. doi: 10.1073/pnas.1700946114. Epub 2017 Apr 10.


Expression of GARP Is Increased in Tumor-Infiltrating Regulatory T Cells and Is Correlated to Clinicopathology of Lung Cancer Patients.

Jin H, Sun L, Tang L, Yu W, Li H.

Front Immunol. 2017 Feb 14;8:138. doi: 10.3389/fimmu.2017.00138. eCollection 2017.


Genetic and epigenetic studies of FOXP3 in asthma and allergy.

Marques CR, Costa RS, Costa GNO, da Silva TM, Teixeira TO, de Andrade EMM, Galvão AA, Carneiro VL, Figueiredo CA.

Asthma Res Pract. 2015 Oct 20;1:10. doi: 10.1186/s40733-015-0012-4. eCollection 2015.


Functional defects in CD4+ CD25high FoxP3+ regulatory cells in ankylosing spondylitis.

Guo H, Zheng M, Zhang K, Yang F, Zhang X, Han Q, Chen ZN, Zhu P.

Sci Rep. 2016 Nov 30;6:37559. doi: 10.1038/srep37559.


Proteomic Approaches to Biomarker Discovery in Cutaneous T-Cell Lymphoma.

Ion A, Popa IM, Papagheorghe LM, Lisievici C, Lupu M, Voiculescu V, Caruntu C, Boda D.

Dis Markers. 2016;2016:9602472. Epub 2016 Oct 16. Review.


Control of inflammation by stromal Hedgehog pathway activation restrains colitis.

Lee JJ, Rothenberg ME, Seeley ES, Zimdahl B, Kawano S, Lu WJ, Shin K, Sakata-Kato T, Chen JK, Diehn M, Clarke MF, Beachy PA.

Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7545-E7553. Epub 2016 Nov 4.


CD4+ Foxp3+ T cells promote aberrant immunoglobulin G production and maintain CD8+ T-cell suppression during chronic liver disease.

Tedesco D, Thapa M, Gumber S, Elrod EJ, Rahman K, Ibegbu CC, Magliocca JF, Adams AB, Anania F, Grakoui A.

Hepatology. 2017 Feb;65(2):661-677. doi: 10.1002/hep.28894. Epub 2016 Dec 19.


Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression.

Gerriets VA, Kishton RJ, Johnson MO, Cohen S, Siska PJ, Nichols AG, Warmoes MO, de Cubas AA, MacIver NJ, Locasale JW, Turka LA, Wells AD, Rathmell JC.

Nat Immunol. 2016 Dec;17(12):1459-1466. doi: 10.1038/ni.3577. Epub 2016 Oct 3.


Restoring immune tolerance in neuromyelitis optica: Part II.

Bar-Or A, Steinman L, Behne JM, Benitez-Ribas D, Chin PS, Clare-Salzler M, Healey D, Kim JI, Kranz DM, Lutterotti A, Martin R, Schippling S, Villoslada P, Wei CH, Weiner HL, Zamvil SS, Smith TJ, Yeaman MR.

Neurol Neuroimmunol Neuroinflamm. 2016 Sep 7;3(5):e277. doi: 10.1212/NXI.0000000000000277. eCollection 2016 Oct. Review.


Maternal allergic disease history affects childhood allergy development through impairment of neonatal regulatory T-cells.

Meng SS, Gao R, Yan BD, Ren J, Wu F, Chen P, Zhang J, Wang LF, Xiao YM, Liu J.

Respir Res. 2016 Sep 20;17(1):114. doi: 10.1186/s12931-016-0430-8. Erratum in: Respir Res. 2016 Oct 21;17 (1):134.

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