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Items: 1 to 20 of 116

1.

VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair.

van den Boom J, Wolf M, Weimann L, Schulze N, Li F, Kaschani F, Riemer A, Zierhut C, Kaiser M, Iliakis G, Funabiki H, Meyer H.

Mol Cell. 2016 Oct 6;64(1):189-198. doi: 10.1016/j.molcel.2016.08.037.

PMID:
27716483
2.

The life cycle of the 26S proteasome: from birth, through regulation and function, and onto its death.

Livneh I, Cohen-Kaplan V, Cohen-Rosenzweig C, Avni N, Ciechanover A.

Cell Res. 2016 Aug;26(8):869-85. doi: 10.1038/cr.2016.86. Epub 2016 Jul 22. Review.

3.

Valosin-containing protein (VCP)-Adaptor Interactions are Exceptionally Dynamic and Subject to Differential Modulation by a VCP Inhibitor.

Xue L, Blythe EE, Freiberger EC, Mamrosh JL, Hebert AS, Reitsma JM, Hess S, Coon JJ, Deshaies RJ.

Mol Cell Proteomics. 2016 Sep;15(9):2970-86. doi: 10.1074/mcp.M116.061036. Epub 2016 Jul 12.

PMID:
27406709
4.

Hepatic cytochromes P450: structural degrons and barcodes, posttranslational modifications and cellular adapters in the ERAD-endgame.

Kim SM, Wang Y, Nabavi N, Liu Y, Correia MA.

Drug Metab Rev. 2016 Aug;48(3):405-33. doi: 10.1080/03602532.2016.1195403. Epub 2016 Jun 20.

PMID:
27320797
5.

p97 Disease Mutations Modulate Nucleotide-Induced Conformation to Alter Protein-Protein Interactions.

Bulfer SL, Chou TF, Arkin MR.

ACS Chem Biol. 2016 Aug 19;11(8):2112-6. doi: 10.1021/acschembio.6b00350. Epub 2016 Jun 13.

PMID:
27267671
6.

Ring of Change: CDC48/p97 Drives Protein Dynamics at Chromatin.

Franz A, Ackermann L, Hoppe T.

Front Genet. 2016 May 3;7:73. doi: 10.3389/fgene.2016.00073. eCollection 2016. Review.

7.

The Myoblast C2C12 Transfected with Mutant Valosin-Containing Protein Exhibits Delayed Stress Granule Resolution on Oxidative Stress.

Rodriguez-Ortiz CJ, Flores JC, Valenzuela JA, Rodriguez GJ, Zumkehr J, Tran DN, Kimonis VE, Kitazawa M.

Am J Pathol. 2016 Jun;186(6):1623-34. doi: 10.1016/j.ajpath.2016.02.007. Epub 2016 Apr 20.

PMID:
27106764
8.

Oxaspirol B with p97 Inhibitory Activity and Other Oxaspirols from Lecythophora sp. FL1375 and FL1031, Endolichenic Fungi Inhabiting Parmotrema tinctorum and Cladonia evansii.

Wijeratne EM, Gunaherath GM, Chapla VM, Tillotson J, de la Cruz F, Kang M, U'Ren JM, Araujo AR, Arnold AE, Chapman E, Gunatilaka AA.

J Nat Prod. 2016 Feb 26;79(2):340-52. doi: 10.1021/acs.jnatprod.5b00986. Epub 2016 Jan 26.

9.

The Ankrd13 Family of Ubiquitin-interacting Motif-bearing Proteins Regulates Valosin-containing Protein/p97 Protein-mediated Lysosomal Trafficking of Caveolin 1.

Burana D, Yoshihara H, Tanno H, Yamamoto A, Saeki Y, Tanaka K, Komada M.

J Biol Chem. 2016 Mar 18;291(12):6218-31. doi: 10.1074/jbc.M115.710707. Epub 2016 Jan 21.

10.

INO80 Chromatin Remodeler Facilitates Release of RNA Polymerase II from Chromatin for Ubiquitin-Mediated Proteasomal Degradation.

Lafon A, Taranum S, Pietrocola F, Dingli F, Loew D, Brahma S, Bartholomew B, Papamichos-Chronakis M.

Mol Cell. 2015 Dec 3;60(5):784-96. doi: 10.1016/j.molcel.2015.10.028. Epub 2015 Nov 19.

11.

Origin and Functional Evolution of the Cdc48/p97/VCP AAA+ Protein Unfolding and Remodeling Machine.

Barthelme D, Sauer RT.

J Mol Biol. 2016 May 8;428(9 Pt B):1861-9. doi: 10.1016/j.jmb.2015.11.015. Epub 2015 Dec 1. Review.

PMID:
26608813
12.

The N-terminal Region of the Ubiquitin Regulatory X (UBX) Domain-containing Protein 1 (UBXD1) Modulates Interdomain Communication within the Valosin-containing Protein p97.

Trusch F, Matena A, Vuk M, Koerver L, Knævelsrud H, Freemont PS, Meyer H, Bayer P.

J Biol Chem. 2015 Dec 4;290(49):29414-27. doi: 10.1074/jbc.M115.680686. Epub 2015 Oct 16.

13.

p97/VCP promotes Cullin-RING-ubiquitin-ligase/proteasome-dependent degradation of IκBα and the preceding liberation of RelA from ubiquitinated IκBα.

Schweitzer K, Pralow A, Naumann M.

J Cell Mol Med. 2016 Jan;20(1):58-70. doi: 10.1111/jcmm.12702. Epub 2015 Oct 14.

14.

XPC: Going where no DNA damage sensor has gone before.

Nemzow L, Lubin A, Zhang L, Gong F.

DNA Repair (Amst). 2015 Dec;36:19-27. doi: 10.1016/j.dnarep.2015.09.004. Epub 2015 Sep 9. Review.

15.

Proteomics of yeast telomerase identified Cdc48-Npl4-Ufd1 and Ufd4 as regulators of Est1 and telomere length.

Lin KW, McDonald KR, Guise AJ, Chan A, Cristea IM, Zakian VA.

Nat Commun. 2015 Sep 14;6:8290. doi: 10.1038/ncomms9290.

16.

FBG1 Is the Final Arbitrator of A1AT-Z Degradation.

Wen JH, Wen H, Gibson-Corley KN, Glenn KA.

PLoS One. 2015 Aug 21;10(8):e0135591. doi: 10.1371/journal.pone.0135591. eCollection 2015.

17.

DNAJs: more than substrate delivery to HSPA.

Dekker SL, Kampinga HH, Bergink S.

Front Mol Biosci. 2015 Jun 30;2:35. doi: 10.3389/fmolb.2015.00035. eCollection 2015. Review.

18.

Withaferin A Analogs That Target the AAA+ Chaperone p97.

Tao S, Tillotson J, Wijeratne EM, Xu YM, Kang M, Wu T, Lau EC, Mesa C, Mason DJ, Brown RV, La Clair JJ, Gunatilaka AA, Zhang DD, Chapman E.

ACS Chem Biol. 2015 Aug 21;10(8):1916-24. doi: 10.1021/acschembio.5b00367. Epub 2015 Jun 3.

19.

Termination of DNA replication forks: "Breaking up is hard to do".

Bailey R, Priego Moreno S, Gambus A.

Nucleus. 2015;6(3):187-96. doi: 10.1080/19491034.2015.1035843. Epub 2015 Apr 2.

20.

Role of the deubiquitylating enzyme DmUsp5 in coupling ubiquitin equilibrium to development and apoptosis in Drosophila melanogaster.

Kovács L, Nagy O, Pál M, Udvardy A, Popescu O, Deák P.

PLoS One. 2015 Mar 25;10(3):e0120875. doi: 10.1371/journal.pone.0120875. eCollection 2015.

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