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Lactase persistence in Tunisia as a result of admixture with other Mediterranean populations.

Ben Halima Y, Kefi R, Sazzini M, Giuliani C, De Fanti S, Nouali C, Nagara M, Mengozzi G, Elouej S, Abid A, Jamoussi H, Chouchane L, Romeo G, Abdelhak S, Luiselli D.

Genes Nutr. 2017 Aug 24;12:20. doi: 10.1186/s12263-017-0573-3. eCollection 2017.


Inferences of African evolutionary history from genomic data.

Beltrame MH, Rubel MA, Tishkoff SA.

Curr Opin Genet Dev. 2016 Dec;41:159-166. doi: 10.1016/j.gde.2016.10.002. Epub 2016 Nov 1. Review.


In Vitro Functional Analyses of Infrequent Nucleotide Variants in the Lactase Enhancer Reveal Different Molecular Routes to Increased Lactase Promoter Activity and Lactase Persistence.

Liebert A, Jones BL, Danielsen ET, Olsen AK, Swallow DM, Troelsen JT.

Ann Hum Genet. 2016 Nov;80(6):307-318. doi: 10.1111/ahg.12167. Epub 2016 Oct 7.


Clinical evaluation, biochemistry and genetic polymorphism analysis for the diagnosis of lactose intolerance in a population from northeastern Brazil.

Ponte PR, de Medeiros PH, Havt A, Caetano JA, Cid DA, Prata Mde M, Soares AM, Guerrant RL, Mychaleckyj J, Lima AÂ.

Clinics (Sao Paulo). 2016 Feb;71(2):82-9. doi: 10.6061/clinics/2016(02)06. Review.


Genetic diversity of lactase persistence in East African populations.

Hassan HY, van Erp A, Jaeger M, Tahir H, Oosting M, Joosten LA, Netea MG.

BMC Res Notes. 2016 Jan 4;9:8. doi: 10.1186/s13104-015-1833-1.


Lactose Intolerance in Adults: Biological Mechanism and Dietary Management.

Deng Y, Misselwitz B, Dai N, Fox M.

Nutrients. 2015 Sep 18;7(9):8020-35. doi: 10.3390/nu7095380. Review.


The Diverse Forms of Lactose Intolerance and the Putative Linkage to Several Cancers.

Amiri M, Diekmann L, von Köckritz-Blickwede M, Naim HY.

Nutrients. 2015 Aug 28;7(9):7209-30. doi: 10.3390/nu7095332. Review.


Phylogeographic Refinement and Large Scale Genotyping of Human Y Chromosome Haplogroup E Provide New Insights into the Dispersal of Early Pastoralists in the African Continent.

Trombetta B, D'Atanasio E, Massaia A, Ippoliti M, Coppa A, Candilio F, Coia V, Russo G, Dugoujon JM, Moral P, Akar N, Sellitto D, Valesini G, Novelletto A, Scozzari R, Cruciani F.

Genome Biol Evol. 2015 Jun 24;7(7):1940-50. doi: 10.1093/gbe/evv118.


Diversity of lactase persistence in African milk drinkers.

Jones BL, Oljira T, Liebert A, Zmarz P, Montalva N, Tarekeyn A, Ekong R, Thomas MG, Bekele E, Bradman N, Swallow DM.

Hum Genet. 2015 Aug;134(8):917-25. doi: 10.1007/s00439-015-1573-2. Epub 2015 Jun 9.


Adult lactose digestion status and effects on disease.

Szilagyi A.

Can J Gastroenterol Hepatol. 2015 Apr;29(3):149-56. Review.


Evolutionary genetics as a tool to target genes involved in phenotypes of medical relevance.

Heyer E, Quintana-Murci L.

Evol Appl. 2009 Feb;2(1):71-80. doi: 10.1111/j.1752-4571.2008.00061.x.


The great opportunity: Evolutionary applications to medicine and public health.

Nesse RM, Stearns SC.

Evol Appl. 2008 Feb;1(1):28-48. doi: 10.1111/j.1752-4571.2007.00006.x.


The lactase persistence genotype is a protective factor for the metabolic syndrome.

Friedrich DC, de Andrade FM, Fiegenbaum M, de Almeida S, Mattevi VS, Callegari-Jacques SM, Hutz MH.

Genet Mol Biol. 2014 Oct;37(4):611-5. doi: 10.1590/S1415-47572014005000012. Epub 2014 Oct 21.


Population Genomics of Human Adaptation.

Lachance J, Tishkoff SA.

Annu Rev Ecol Evol Syst. 2013 Nov;44:123-143.


Adaptations to local environments in modern human populations.

Jeong C, Di Rienzo A.

Curr Opin Genet Dev. 2014 Dec;29:1-8. doi: 10.1016/j.gde.2014.06.011. Epub 2014 Aug 15. Review.


Genetic variation and adaptation in Africa: implications for human evolution and disease.

Gomez F, Hirbo J, Tishkoff SA.

Cold Spring Harb Perspect Biol. 2014 Jul 1;6(7):a008524. doi: 10.1101/cshperspect.a008524. Review.


Editors' Pick: milk sugar, migration and pastoralism in Africa.

Sajantila A.

Investig Genet. 2014 Mar 31;5(1):5. doi: 10.1186/2041-2223-5-5. No abstract available.


Genetic origins of lactase persistence and the spread of pastoralism in Africa.

Ranciaro A, Campbell MC, Hirbo JB, Ko WY, Froment A, Anagnostou P, Kotze MJ, Ibrahim M, Nyambo T, Omar SA, Tishkoff SA.

Am J Hum Genet. 2014 Apr 3;94(4):496-510. doi: 10.1016/j.ajhg.2014.02.009. Epub 2014 Mar 13.


Ancient DNA analysis reveals high frequency of European lactase persistence allele (T-13910) in medieval central europe.

Krüttli A, Bouwman A, Akgül G, Della Casa P, Rühli F, Warinner C.

PLoS One. 2014 Jan 23;9(1):e86251. doi: 10.1371/journal.pone.0086251. eCollection 2014.

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