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Items: 1 to 20 of 42


APOBEC3G-Mediated G-to-A Hypermutation of the HIV-1 Genome: The Missing Link in Antiviral Molecular Mechanisms.

Okada A, Iwatani Y.

Front Microbiol. 2016 Dec 19;7:2027. doi: 10.3389/fmicb.2016.02027. eCollection 2016. Review.


Crystal structures of APOBEC3G N-domain alone and its complex with DNA.

Xiao X, Li SX, Yang H, Chen XS.

Nat Commun. 2016 Aug 2;7:12193. doi: 10.1038/ncomms12193.


The APOBEC Protein Family: United by Structure, Divergent in Function.

Salter JD, Bennett RP, Smith HC.

Trends Biochem Sci. 2016 Jul;41(7):578-94. doi: 10.1016/j.tibs.2016.05.001. Epub 2016 Jun 6. Review.


Structural and functional assessment of APOBEC3G macromolecular complexes.

Polevoda B, McDougall WM, Bennett RP, Salter JD, Smith HC.

Methods. 2016 Sep 1;107:10-22. doi: 10.1016/j.ymeth.2016.03.006. Epub 2016 Mar 14.


RNA binding to APOBEC3G induces the disassembly of functional deaminase complexes by displacing single-stranded DNA substrates.

Polevoda B, McDougall WM, Tun BN, Cheung M, Salter JD, Friedman AE, Smith HC.

Nucleic Acids Res. 2015 Oct 30;43(19):9434-45. doi: 10.1093/nar/gkv970. Epub 2015 Sep 30.


Characterization of the Catalytic Domain of Human APOBEC3B and the Critical Structural Role for a Conserved Methionine.

Siriwardena SU, Guruge TA, Bhagwat AS.

J Mol Biol. 2015 Sep 25;427(19):3042-55. doi: 10.1016/j.jmb.2015.08.006. Epub 2015 Aug 14.


The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization.

Bohn MF, Shandilya SM, Silvas TV, Nalivaika EA, Kouno T, Kelch BA, Ryder SP, Kurt-Yilmaz N, Somasundaran M, Schiffer CA.

Structure. 2015 May 5;23(5):903-11. doi: 10.1016/j.str.2015.03.016. Epub 2015 Apr 23.


Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA.

Lu X, Zhang T, Xu Z, Liu S, Zhao B, Lan W, Wang C, Ding J, Cao C.

J Biol Chem. 2015 Feb 13;290(7):4010-21. doi: 10.1074/jbc.M114.624262. Epub 2014 Dec 25.


The multifaceted roles of RNA binding in APOBEC cytidine deaminase functions.

Prohaska KM, Bennett RP, Salter JD, Smith HC.

Wiley Interdiscip Rev RNA. 2014 Jul-Aug;5(4):493-508. doi: 10.1002/wrna.1226. Epub 2014 Mar 24. Review.


APOBEC3 multimerization correlates with HIV-1 packaging and restriction activity in living cells.

Li J, Chen Y, Li M, Carpenter MA, McDougle RM, Luengas EM, Macdonald PJ, Harris RS, Mueller JD.

J Mol Biol. 2014 Mar 20;426(6):1296-307. doi: 10.1016/j.jmb.2013.12.014. Epub 2013 Dec 17.


Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all.

Desimmie BA, Delviks-Frankenberrry KA, Burdick RC, Qi D, Izumi T, Pathak VK.

J Mol Biol. 2014 Mar 20;426(6):1220-45. doi: 10.1016/j.jmb.2013.10.033. Epub 2013 Nov 2. Review.


Atomic force microscopy studies of APOBEC3G oligomerization and dynamics.

Shlyakhtenko LS, Lushnikov AY, Miyagi A, Li M, Harris RS, Lyubchenko YL.

J Struct Biol. 2013 Nov;184(2):217-25. doi: 10.1016/j.jsb.2013.09.008. Epub 2013 Sep 18.


The role of cytidine deaminases on innate immune responses against human viral infections.

Vieira VC, Soares MA.

Biomed Res Int. 2013;2013:683095. doi: 10.1155/2013/683095. Epub 2013 Jun 25. Review.


Binding of RNA by APOBEC3G controls deamination-independent restriction of retroviruses.

BĂ©langer K, Savoie M, Rosales Gerpe MC, Couture JF, Langlois MA.

Nucleic Acids Res. 2013 Aug;41(15):7438-52. doi: 10.1093/nar/gkt527. Epub 2013 Jun 12.


Retroviral restriction factor APOBEC3G delays the initiation of DNA synthesis by HIV-1 reverse transcriptase.

Adolph MB, Webb J, Chelico L.

PLoS One. 2013 May 23;8(5):e64196. doi: 10.1371/journal.pone.0064196. Print 2013.


Impact of H216 on the DNA binding and catalytic activities of the HIV restriction factor APOBEC3G.

Harjes S, Solomon WC, Li M, Chen KM, Harjes E, Harris RS, Matsuo H.

J Virol. 2013 Jun;87(12):7008-14. doi: 10.1128/JVI.03173-12. Epub 2013 Apr 17.


HIV-1 viral infectivity factor (Vif) alters processive single-stranded DNA scanning of the retroviral restriction factor APOBEC3G.

Feng Y, Love RP, Chelico L.

J Biol Chem. 2013 Mar 1;288(9):6083-94. doi: 10.1074/jbc.M112.421875. Epub 2013 Jan 11.


Random mutagenesis MAPPIT analysis identifies binding sites for Vif and Gag in both cytidine deaminase domains of Apobec3G.

Uyttendaele I, Lavens D, Catteeuw D, Lemmens I, Bovijn C, Tavernier J, Peelman F.

PLoS One. 2012;7(9):e44143. doi: 10.1371/journal.pone.0044143. Epub 2012 Sep 10.


Antiviral Mechanism and Biochemical Basis of the Human APOBEC3 Family.

Imahashi M, Nakashima M, Iwatani Y.

Front Microbiol. 2012 Jul 9;3:250. doi: 10.3389/fmicb.2012.00250. eCollection 2012.


Towards Inhibition of Vif-APOBEC3G Interaction: Which Protein to Target?

Cadima-Couto I, Goncalves J.

Adv Virol. 2010;2010:649315. doi: 10.1155/2010/649315. Epub 2010 Sep 21.

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